Summary ?
GeneID283234
SymbolCCDC88B
SynonymsBRLZ|CCDC88|HKRP3|gipie
Descriptioncoiled-coil domain containing 88B
ReferenceMIM:611205|HGNC:HGNC:26757|Ensembl:ENSG00000168071|HPRD:10986|Vega:OTTHUMG00000045419
Gene typeprotein-coding
Map location11q12.3
Pascal p-value0.234
Sherlock p-value0.884
DMG1 (# studies)
eGeneCaudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9
Putamen basal ganglia
Myers' cis & trans
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Wockner_2014Genome-wide DNA methylation analysisThis dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 2

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg080248871164108241CCDC88B1.089E-4-0.4090.028DMG:Wockner_2014
cg261071001164112546CCDC88B2.604E-40.2990.038DMG:Wockner_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs17392743chr154764240CCDC88B2832340.15trans
rs2502827chr1176044216CCDC88B2832340.03trans
rs17572651chr1218943612CCDC88B2832340.02trans
rs16829545chr2151977407CCDC88B2832341.577E-14trans
rs16858054chr2171105787CCDC88B2832340.11trans
rs3845734chr2171125572CCDC88B2832342.454E-4trans
rs7584986chr2184111432CCDC88B2832343.671E-8trans
rs17762315chr576807576CCDC88B2832340.01trans
rs7729096chr576835927CCDC88B2832340.08trans
rs11738579chr595119841CCDC88B2832340.18trans
rs16890367chr638078448CCDC88B2832340.09trans
rs3118341chr925185518CCDC88B2832340.12trans
rs11139334chr984209393CCDC88B2832347.845E-4trans
rs2766987chr9113667956CCDC88B2832340.18trans
rs3765543chr9134458323CCDC88B2832340.1trans
rs2393316chr1059333070CCDC88B2832340.01trans
rs16955618chr1529937543CCDC88B2832342.253E-25trans
rs1041786chr2122617710CCDC88B2832344.193E-4trans
rs6471521164109118CCDC88BENSG00000168071.171.358E-60.021423gtex_brain_putamen_basal
rs4795521164110683CCDC88BENSG00000168071.171.364E-60.022988gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
IVANOVA HEMATOPOIESIS LATE PROGENITOR 544307All SZGR 2.0 genes in this pathway
MIKKELSEN IPS LCP WITH H3K4ME3 174100All SZGR 2.0 genes in this pathway
MARTENS BOUND BY PML RARA FUSION 456287All SZGR 2.0 genes in this pathway
LIM MAMMARY LUMINAL PROGENITOR UP 5830All SZGR 2.0 genes in this pathway