Gene Page: EXOC3L1
Summary ?
| GeneID | 283849 |
| Symbol | EXOC3L1 |
| Synonyms | EXOC3L |
| Description | exocyst complex component 3-like 1 |
| Reference | MIM:614117|HGNC:HGNC:27540|Ensembl:ENSG00000179044|HPRD:14148|Vega:OTTHUMG00000137508 |
| Gene type | protein-coding |
| Map location | 16q22.1 |
| Pascal p-value | 0.144 |
| DMG | 1 (# studies) |
| eGene | Myers' cis & trans Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| DMG:Jaffe_2016 | Genome-wide DNA methylation analysis | This dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05. | 1 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
| Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| cg10947003 | 16 | 67218230 | EXOC3L1 | 5.58E-10 | -0.016 | 8.9E-7 | DMG:Jaffe_2016 |
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs16829545 | chr2 | 151977407 | EXOC3L1 | 283849 | 0.02 | trans | ||
| rs16878317 | chr8 | 31657853 | EXOC3L1 | 283849 | 0.14 | trans | ||
| rs16955618 | chr15 | 29937543 | EXOC3L1 | 283849 | 8.59E-4 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| MIKKELSEN IPS LCP WITH H3K4ME3 | 174 | 100 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN ES LCP WITH H3K4ME3 | 142 | 80 | All SZGR 2.0 genes in this pathway |