Gene Page: TTC28-AS1
Summary ?
| GeneID | 284900 |
| Symbol | TTC28-AS1 |
| Synonyms | TTC28-AS|TTC28AS|dJ353E16.2 |
| Description | TTC28 antisense RNA 1 |
| Reference | HGNC:HGNC:29336|Ensembl:ENSG00000235954| |
| Gene type | ncRNA |
| Map location | 22q12.1 |
| Pascal p-value | 0.045 |
| eGene | Anterior cingulate cortex BA24 Caudate basal ganglia Cerebellum Cortex Nucleus accumbens basal ganglia Putamen basal ganglia |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs2267127 | 22 | 28294801 | TTC28-AS1 | ENSG00000235954.2 | 1.264E-6 | 0.02 | -20563 | gtex_brain_ba24 |
| rs738454 | 22 | 28305509 | TTC28-AS1 | ENSG00000235954.2 | 1.486E-6 | 0.02 | -9855 | gtex_brain_ba24 |
| rs1807581 | 22 | 28306070 | TTC28-AS1 | ENSG00000235954.2 | 3.42E-7 | 0.02 | -9294 | gtex_brain_ba24 |
| rs5762399 | 22 | 28306607 | TTC28-AS1 | ENSG00000235954.2 | 5.394E-7 | 0.02 | -8757 | gtex_brain_ba24 |
| rs56156048 | 22 | 28312564 | TTC28-AS1 | ENSG00000235954.2 | 1.587E-6 | 0.02 | -2800 | gtex_brain_ba24 |
| rs9613545 | 22 | 28336162 | TTC28-AS1 | ENSG00000235954.2 | 1.264E-6 | 0.02 | 20798 | gtex_brain_ba24 |
| rs2267127 | 22 | 28294801 | TTC28-AS1 | ENSG00000235954.2 | 6.567E-8 | 0 | -20563 | gtex_brain_putamen_basal |
| rs738454 | 22 | 28305509 | TTC28-AS1 | ENSG00000235954.2 | 5.474E-8 | 0 | -9855 | gtex_brain_putamen_basal |
| rs1807581 | 22 | 28306070 | TTC28-AS1 | ENSG00000235954.2 | 3.966E-8 | 0 | -9294 | gtex_brain_putamen_basal |
| rs5762399 | 22 | 28306607 | TTC28-AS1 | ENSG00000235954.2 | 1.61E-7 | 0 | -8757 | gtex_brain_putamen_basal |
| rs56156048 | 22 | 28312564 | TTC28-AS1 | ENSG00000235954.2 | 5.65E-8 | 0 | -2800 | gtex_brain_putamen_basal |
| rs7292046 | 22 | 28314113 | TTC28-AS1 | ENSG00000235954.2 | 1.478E-7 | 0 | -1251 | gtex_brain_putamen_basal |
| rs16985722 | 22 | 28315465 | TTC28-AS1 | ENSG00000235954.2 | 1.084E-9 | 0 | 101 | gtex_brain_putamen_basal |
| rs2267128 | 22 | 28316173 | TTC28-AS1 | ENSG00000235954.2 | 1.085E-9 | 0 | 809 | gtex_brain_putamen_basal |
| rs12483793 | 22 | 28319511 | TTC28-AS1 | ENSG00000235954.2 | 3.643E-7 | 0 | 4147 | gtex_brain_putamen_basal |
| rs12484349 | 22 | 28329949 | TTC28-AS1 | ENSG00000235954.2 | 2.017E-7 | 0 | 14585 | gtex_brain_putamen_basal |
| rs9613545 | 22 | 28336162 | TTC28-AS1 | ENSG00000235954.2 | 1.023E-7 | 0 | 20798 | gtex_brain_putamen_basal |
| rs2294818 | 22 | 28386322 | TTC28-AS1 | ENSG00000235954.2 | 6.977E-7 | 0 | 70958 | gtex_brain_putamen_basal |
| rs78439401 | 22 | 28395314 | TTC28-AS1 | ENSG00000235954.2 | 1.351E-7 | 0 | 79950 | gtex_brain_putamen_basal |
| rs16985863 | 22 | 28405165 | TTC28-AS1 | ENSG00000235954.2 | 6.754E-8 | 0 | 89801 | gtex_brain_putamen_basal |
| rs8138623 | 22 | 28406672 | TTC28-AS1 | ENSG00000235954.2 | 1.257E-7 | 0 | 91308 | gtex_brain_putamen_basal |
| rs78320689 | 22 | 28407763 | TTC28-AS1 | ENSG00000235954.2 | 1.232E-8 | 0 | 92399 | gtex_brain_putamen_basal |
| rs75650828 | 22 | 28415655 | TTC28-AS1 | ENSG00000235954.2 | 1.139E-7 | 0 | 100291 | gtex_brain_putamen_basal |
| rs2076505 | 22 | 28424507 | TTC28-AS1 | ENSG00000235954.2 | 5.832E-7 | 0 | 109143 | gtex_brain_putamen_basal |
| rs2235713 | 22 | 28430652 | TTC28-AS1 | ENSG00000235954.2 | 1.23E-7 | 0 | 115288 | gtex_brain_putamen_basal |
| rs9613563 | 22 | 28433076 | TTC28-AS1 | ENSG00000235954.2 | 5.402E-8 | 0 | 117712 | gtex_brain_putamen_basal |
| rs79037983 | 22 | 28459665 | TTC28-AS1 | ENSG00000235954.2 | 9.751E-8 | 0 | 144301 | gtex_brain_putamen_basal |
| rs8137183 | 22 | 28477312 | TTC28-AS1 | ENSG00000235954.2 | 2.785E-8 | 0 | 161948 | gtex_brain_putamen_basal |
| rs75503143 | 22 | 28510690 | TTC28-AS1 | ENSG00000235954.2 | 1.372E-6 | 0 | 195326 | gtex_brain_putamen_basal |
| rs135646 | 22 | 28541075 | TTC28-AS1 | ENSG00000235954.2 | 4.257E-8 | 0 | 225711 | gtex_brain_putamen_basal |
| rs5762511 | 22 | 28575543 | TTC28-AS1 | ENSG00000235954.2 | 2.047E-7 | 0 | 260179 | gtex_brain_putamen_basal |
| rs77242046 | 22 | 28613261 | TTC28-AS1 | ENSG00000235954.2 | 7.558E-7 | 0 | 297897 | gtex_brain_putamen_basal |
| rs134171 | 22 | 28613262 | TTC28-AS1 | ENSG00000235954.2 | 7.558E-7 | 0 | 297898 | gtex_brain_putamen_basal |
| rs16986354 | 22 | 28754648 | TTC28-AS1 | ENSG00000235954.2 | 1.272E-6 | 0 | 439284 | gtex_brain_putamen_basal |
| rs16986420 | 22 | 28827214 | TTC28-AS1 | ENSG00000235954.2 | 1.014E-6 | 0 | 511850 | gtex_brain_putamen_basal |
| rs16986431 | 22 | 28837904 | TTC28-AS1 | ENSG00000235954.2 | 1.59E-6 | 0 | 522540 | gtex_brain_putamen_basal |
| rs74720230 | 22 | 28894879 | TTC28-AS1 | ENSG00000235954.2 | 1.516E-6 | 0 | 579515 | gtex_brain_putamen_basal |
| rs16986544 | 22 | 28995694 | TTC28-AS1 | ENSG00000235954.2 | 1.59E-6 | 0 | 680330 | gtex_brain_putamen_basal |
| rs202162898 | 22 | 29017546 | TTC28-AS1 | ENSG00000235954.2 | 8.268E-7 | 0 | 702182 | gtex_brain_putamen_basal |
| rs76317571 | 22 | 29017547 | TTC28-AS1 | ENSG00000235954.2 | 9.296E-7 | 0 | 702183 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KONDO EZH2 TARGETS | 245 | 148 | All SZGR 2.0 genes in this pathway |
| CERIBELLI GENES INACTIVE AND BOUND BY NFY | 45 | 27 | All SZGR 2.0 genes in this pathway |
| PEDRIOLI MIR31 TARGETS UP | 221 | 120 | All SZGR 2.0 genes in this pathway |