Summary ?
GeneID286257
SymbolC9orf142
SynonymsPAXX
Descriptionchromosome 9 open reading frame 142
ReferenceMIM:616315|HGNC:HGNC:27849|Ensembl:ENSG00000148362|HPRD:14163|Vega:OTTHUMG00000020971
Gene typeprotein-coding
Map location9q34.3
Pascal p-value0.798
Fetal beta-0.088
DMG1 (# studies)
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9
Nucleus accumbens basal ganglia
Putamen basal ganglia
Myers' cis & trans
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
DMG:vanEijk_2014Genome-wide DNA methylation analysisThis dataset includes 432 differentially methylated CpG sites corresponding to 391 unique transcripts between schizophrenia patients (n=260) and unaffected controls (n=250). 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg070781149139606202C9orf1427.574E-46.03DMG:vanEijk_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs1578978chr8118196802C9orf1422862570.08trans
rs78604309139884447C9orf142ENSG00000148362.61.25E-60-2423gtex_brain_ba24
rs108701569139885539C9orf142ENSG00000148362.64.464E-70-1331gtex_brain_ba24
rs108701579139885762C9orf142ENSG00000148362.62.147E-80-1108gtex_brain_ba24
rs108701589139885820C9orf142ENSG00000148362.66.814E-80-1050gtex_brain_ba24
rs107815309139885948C9orf142ENSG00000148362.66.812E-80-922gtex_brain_ba24
rs108701599139887042C9orf142ENSG00000148362.67.771E-80172gtex_brain_ba24
rs74708679139893123C9orf142ENSG00000148362.67.036E-806253gtex_brain_ba24
rs65606539139894003C9orf142ENSG00000148362.62.069E-807133gtex_brain_ba24
rs70323819139894331C9orf142ENSG00000148362.65.626E-807461gtex_brain_ba24
rs70223479139894332C9orf142ENSG00000148362.62.997E-807462gtex_brain_ba24
rs123407779139895429C9orf142ENSG00000148362.64.096E-808559gtex_brain_ba24
rs672121199139895465C9orf142ENSG00000148362.61.073E-608595gtex_brain_ba24
rs123396739139895482C9orf142ENSG00000148362.68.075E-708612gtex_brain_ba24
rs78548389139895514C9orf142ENSG00000148362.61.327E-708644gtex_brain_ba24
rs73886719139895998C9orf142ENSG00000148362.63.99E-809128gtex_brain_ba24
rs73901549139896164C9orf142ENSG00000148362.61.331E-909294gtex_brain_ba24
rs73886969139896168C9orf142ENSG00000148362.63.055E-909298gtex_brain_ba24
rs1998974669139896671C9orf142ENSG00000148362.61.36E-709801gtex_brain_ba24
rs20490409139897164C9orf142ENSG00000148362.63.934E-8010294gtex_brain_ba24
rs1997577009139897983C9orf142ENSG00000148362.69.755E-7011113gtex_brain_ba24
rs43558839139899265C9orf142ENSG00000148362.61.436E-7012395gtex_brain_ba24
rs560650279139899296C9orf142ENSG00000148362.61.101E-6012426gtex_brain_ba24
rs45765159139899352C9orf142ENSG00000148362.61.815E-7012482gtex_brain_ba24
rs590311449139903352C9orf142ENSG00000148362.66.745E-8016482gtex_brain_ba24
rs70485679139904037C9orf142ENSG00000148362.64.563E-8017167gtex_brain_ba24
rs78497059139869608C9orf142ENSG00000148362.62.508E-60-17262gtex_brain_putamen_basal
rs38144999139869914C9orf142ENSG00000148362.61.829E-60-16956gtex_brain_putamen_basal
rs38145009139870090C9orf142ENSG00000148362.61.14E-60-16780gtex_brain_putamen_basal
rs38145019139870113C9orf142ENSG00000148362.61.651E-60-16757gtex_brain_putamen_basal
rs20490439139877129C9orf142ENSG00000148362.61.829E-60-9741gtex_brain_putamen_basal
rs70295659139878317C9orf142ENSG00000148362.61.829E-60-8553gtex_brain_putamen_basal
rs48800829139878828C9orf142ENSG00000148362.61.829E-60-8042gtex_brain_putamen_basal
rs20490419139879113C9orf142ENSG00000148362.61.829E-60-7757gtex_brain_putamen_basal
rs108701549139881127C9orf142ENSG00000148362.61.289E-60-5743gtex_brain_putamen_basal
rs108701559139882740C9orf142ENSG00000148362.61.622E-60-4130gtex_brain_putamen_basal
rs48801829139883413C9orf142ENSG00000148362.61.542E-60-3457gtex_brain_putamen_basal
rs107815299139883948C9orf142ENSG00000148362.63.158E-60-2922gtex_brain_putamen_basal
rs78604309139884447C9orf142ENSG00000148362.62.049E-60-2423gtex_brain_putamen_basal
rs108701579139885762C9orf142ENSG00000148362.65.469E-70-1108gtex_brain_putamen_basal
rs108701589139885820C9orf142ENSG00000148362.61.825E-70-1050gtex_brain_putamen_basal
rs107815309139885948C9orf142ENSG00000148362.61.817E-70-922gtex_brain_putamen_basal
rs108701599139887042C9orf142ENSG00000148362.62.434E-70172gtex_brain_putamen_basal
rs38299029139892629C9orf142ENSG00000148362.61.517E-605759gtex_brain_putamen_basal
rs74708679139893123C9orf142ENSG00000148362.61.452E-706253gtex_brain_putamen_basal
rs727632059139893881C9orf142ENSG00000148362.61.517E-607011gtex_brain_putamen_basal
rs65606539139894003C9orf142ENSG00000148362.65.578E-707133gtex_brain_putamen_basal
rs70323819139894331C9orf142ENSG00000148362.62.728E-607461gtex_brain_putamen_basal
rs70223479139894332C9orf142ENSG00000148362.64.284E-707462gtex_brain_putamen_basal
rs123407779139895429C9orf142ENSG00000148362.61.86E-708559gtex_brain_putamen_basal
rs119997819139895468C9orf142ENSG00000148362.61.642E-608598gtex_brain_putamen_basal
rs123396739139895482C9orf142ENSG00000148362.62.514E-608612gtex_brain_putamen_basal
rs78548389139895514C9orf142ENSG00000148362.63.639E-708644gtex_brain_putamen_basal
rs73886719139895998C9orf142ENSG00000148362.65.788E-709128gtex_brain_putamen_basal
rs73886969139896168C9orf142ENSG00000148362.63.029E-609298gtex_brain_putamen_basal
rs1998974669139896671C9orf142ENSG00000148362.64.494E-709801gtex_brain_putamen_basal
rs20490409139897164C9orf142ENSG00000148362.65.617E-7010294gtex_brain_putamen_basal
rs625858069139897384C9orf142ENSG00000148362.61.521E-6010514gtex_brain_putamen_basal
rs122363309139897927C9orf142ENSG00000148362.62.265E-7011057gtex_brain_putamen_basal
rs111459699139897931C9orf142ENSG00000148362.61.369E-8011061gtex_brain_putamen_basal
rs43558839139899265C9orf142ENSG00000148362.61.073E-7012395gtex_brain_putamen_basal
rs560650279139899296C9orf142ENSG00000148362.65.813E-7012426gtex_brain_putamen_basal
rs45765159139899352C9orf142ENSG00000148362.63.682E-7012482gtex_brain_putamen_basal
rs101144639139899588C9orf142ENSG00000148362.61.524E-6012718gtex_brain_putamen_basal
rs413067329139902166C9orf142ENSG00000148362.61.151E-6015296gtex_brain_putamen_basal
rs590311449139903352C9orf142ENSG00000148362.61.64E-7016482gtex_brain_putamen_basal
rs70485679139904037C9orf142ENSG00000148362.61.009E-7017167gtex_brain_putamen_basal
rs22718629139906359C9orf142ENSG00000148362.69.496E-7019489gtex_brain_putamen_basal
rs22718639139906513C9orf142ENSG00000148362.62.26E-6019643gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
LOPEZ MBD TARGETS 957597All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE UP 857456All SZGR 2.0 genes in this pathway
CHANGOLKAR H2AFY TARGETS DN 4026All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG BOUND 8D 658397All SZGR 2.0 genes in this pathway