Summary ?
GeneID29074
SymbolMRPL18
SynonymsHSPC071|L18mt|MRP-L18
Descriptionmitochondrial ribosomal protein L18
ReferenceMIM:611831|HGNC:HGNC:14477|Ensembl:ENSG00000112110|HPRD:14744|Vega:OTTHUMG00000015942
Gene typeprotein-coding
Map location6q25.3
Pascal p-value0.015
Sherlock p-value0.962
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Putamen basal ganglia
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs93473406160188891MRPL18ENSG00000112110.55.149E-70.01-21953gtex_brain_ba24
rs93473426160193129MRPL18ENSG00000112110.55.149E-70.01-17715gtex_brain_ba24
rs77590866160193853MRPL18ENSG00000112110.55.149E-70.01-16991gtex_brain_ba24
rs159826160199687MRPL18ENSG00000112110.55.149E-70.01-11157gtex_brain_ba24
rs47093686160204127MRPL18ENSG00000112110.55.149E-70.01-6717gtex_brain_ba24
rs93650976160211259MRPL18ENSG00000112110.51.584E-70.01415gtex_brain_ba24
rs22738276160211339MRPL18ENSG00000112110.51.584E-70.01495gtex_brain_ba24
rs22738266160211421MRPL18ENSG00000112110.51.574E-70.01577gtex_brain_ba24
rs22738246160211445MRPL18ENSG00000112110.51.574E-70.01601gtex_brain_ba24
rs22738236160211485MRPL18ENSG00000112110.51.584E-70.01641gtex_brain_ba24
rs11286616160211554MRPL18ENSG00000112110.51.584E-70.01710gtex_brain_ba24
rs11286706160211636MRPL18ENSG00000112110.51.584E-70.01792gtex_brain_ba24
rs585044866160211645MRPL18ENSG00000112110.51.584E-70.01801gtex_brain_ba24
rs27583226160075188MRPL18ENSG00000112110.52.158E-60.01-135656gtex_brain_putamen_basal
rs15354756160148935MRPL18ENSG00000112110.52.76E-60.01-61909gtex_brain_putamen_basal
rs27583126160153452MRPL18ENSG00000112110.52.297E-60.01-57392gtex_brain_putamen_basal
rs113207216160154498MRPL18ENSG00000112110.52.281E-60.01-56346gtex_brain_putamen_basal
rs27583156160158640MRPL18ENSG00000112110.52.297E-60.01-52204gtex_brain_putamen_basal
rs28429746160159034MRPL18ENSG00000112110.52.297E-60.01-51810gtex_brain_putamen_basal
rs58813366160165563MRPL18ENSG00000112110.52.297E-60.01-45281gtex_brain_putamen_basal
rs93650936160175819MRPL18ENSG00000112110.52.297E-60.01-35025gtex_brain_putamen_basal
rs14751236160178007MRPL18ENSG00000112110.52.297E-60.01-32837gtex_brain_putamen_basal
rs19983656160179535MRPL18ENSG00000112110.51.849E-60.01-31309gtex_brain_putamen_basal
rs22770736160182749MRPL18ENSG00000112110.51.189E-60.01-28095gtex_brain_putamen_basal
rs93473396160184890MRPL18ENSG00000112110.52.626E-60.01-25954gtex_brain_putamen_basal
rs1395644606160186711MRPL18ENSG00000112110.52.622E-60.01-24133gtex_brain_putamen_basal
rs93473406160188891MRPL18ENSG00000112110.55.09E-70.01-21953gtex_brain_putamen_basal
rs69051336160192182MRPL18ENSG00000112110.52.29E-60.01-18662gtex_brain_putamen_basal
rs93650956160192928MRPL18ENSG00000112110.52.368E-60.01-17916gtex_brain_putamen_basal
rs93473426160193129MRPL18ENSG00000112110.55.09E-70.01-17715gtex_brain_putamen_basal
rs77588956160193465MRPL18ENSG00000112110.52.297E-60.01-17379gtex_brain_putamen_basal
rs42765256160193612MRPL18ENSG00000112110.52.297E-60.01-17232gtex_brain_putamen_basal
rs77590866160193853MRPL18ENSG00000112110.55.09E-70.01-16991gtex_brain_putamen_basal
rs93557486160194882MRPL18ENSG00000112110.52.297E-60.01-15962gtex_brain_putamen_basal
rs159826160199687MRPL18ENSG00000112110.55.09E-70.01-11157gtex_brain_putamen_basal
rs22959016160201295MRPL18ENSG00000112110.52.297E-60.01-9549gtex_brain_putamen_basal
rs38183006160201677MRPL18ENSG00000112110.52.297E-60.01-9167gtex_brain_putamen_basal
rs47093686160204127MRPL18ENSG00000112110.55.09E-70.01-6717gtex_brain_putamen_basal
rs15470936160205991MRPL18ENSG00000112110.52.297E-60.01-4853gtex_brain_putamen_basal
rs93650976160211259MRPL18ENSG00000112110.55.262E-70.01415gtex_brain_putamen_basal
rs22738276160211339MRPL18ENSG00000112110.55.279E-70.01495gtex_brain_putamen_basal
rs22738266160211421MRPL18ENSG00000112110.55.265E-70.01577gtex_brain_putamen_basal
rs22738246160211445MRPL18ENSG00000112110.55.294E-70.01601gtex_brain_putamen_basal
rs22738236160211485MRPL18ENSG00000112110.55.391E-70.01641gtex_brain_putamen_basal
rs11286616160211554MRPL18ENSG00000112110.55.494E-70.01710gtex_brain_putamen_basal
rs11286706160211636MRPL18ENSG00000112110.55.494E-70.01792gtex_brain_putamen_basal
rs585044866160211645MRPL18ENSG00000112110.55.494E-70.01801gtex_brain_putamen_basal
rs47093756160223618MRPL18ENSG00000112110.52.064E-60.0112774gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
ZHOU INFLAMMATORY RESPONSE LIVE DN 384220All SZGR 2.0 genes in this pathway
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS UP 12672All SZGR 2.0 genes in this pathway
BERENJENO TRANSFORMED BY RHOA UP 536340All SZGR 2.0 genes in this pathway
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP 811508All SZGR 2.0 genes in this pathway
WEI MYCN TARGETS WITH E BOX 795478All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE DN 1237837All SZGR 2.0 genes in this pathway
PAL PRMT5 TARGETS UP 203135All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS PEAK AT 16HR 4024All SZGR 2.0 genes in this pathway
MARSON BOUND BY E2F4 UNSTIMULATED 728415All SZGR 2.0 genes in this pathway
WONG MITOCHONDRIA GENE MODULE 217122All SZGR 2.0 genes in this pathway
ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP 863514All SZGR 2.0 genes in this pathway
WEST ADRENOCORTICAL TUMOR UP 294199All SZGR 2.0 genes in this pathway
MOOTHA HUMAN MITODB 6 2002 429260All SZGR 2.0 genes in this pathway
MOOTHA PGC 420269All SZGR 2.0 genes in this pathway
MOOTHA MITOCHONDRIA 447277All SZGR 2.0 genes in this pathway
GOLDRATH ANTIGEN RESPONSE 346192All SZGR 2.0 genes in this pathway
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 13 172107All SZGR 2.0 genes in this pathway
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 17 181101All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE LATE 1137655All SZGR 2.0 genes in this pathway
LEE BMP2 TARGETS DN 882538All SZGR 2.0 genes in this pathway