Gene Page: FSCN3
Summary ?
GeneID | 29999 |
Symbol | FSCN3 |
Synonyms | - |
Description | fascin actin-bundling protein 3 |
Reference | MIM:615800|HGNC:HGNC:3961|Ensembl:ENSG00000106328|HPRD:17020|Vega:OTTHUMG00000022935 |
Gene type | protein-coding |
Map location | 7q31.3 |
Pascal p-value | 0.044 |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
RGL3 | 0.88 | 0.85 |
PYGM | 0.81 | 0.83 |
FAM38A | 0.79 | 0.78 |
GRIN2C | 0.79 | 0.81 |
GPT | 0.78 | 0.75 |
MICALL2 | 0.78 | 0.65 |
AC012366.1 | 0.78 | 0.73 |
TBX2 | 0.77 | 0.73 |
C1orf175 | 0.77 | 0.80 |
ITGA7 | 0.75 | 0.81 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
UBE2D2 | -0.63 | -0.66 |
ASNSD1 | -0.62 | -0.78 |
FARSB | -0.61 | -0.71 |
MED19 | -0.60 | -0.76 |
TAF9 | -0.60 | -0.70 |
TSG101 | -0.60 | -0.75 |
UBE2E3 | -0.60 | -0.72 |
COQ3 | -0.60 | -0.72 |
RNF139 | -0.59 | -0.68 |
HELQ | -0.59 | -0.67 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | 35 | 25 | All SZGR 2.0 genes in this pathway |
MARTENS TRETINOIN RESPONSE UP | 857 | 456 | All SZGR 2.0 genes in this pathway |