Summary ?
GeneID3026
SymbolHABP2
SynonymsFSAP|HABP|HGFAL|NMTC5|PHBP
Descriptionhyaluronan binding protein 2
ReferenceMIM:603924|HGNC:HGNC:4798|Ensembl:ENSG00000148702|HPRD:04890|Vega:OTTHUMG00000019073
Gene typeprotein-coding
Map location10q25.3
Pascal p-value0.006

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
HBD0.990.99
SCRG10.710.49
LGALS30.690.51
FTL0.680.64
RTP40.670.50
MT30.660.52
CGRRF10.660.43
C1orf610.660.55
PXMP30.660.48
PSMB80.650.57
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
HNRNPUL2-0.57-0.59
MYO18A-0.54-0.54
TRAF3IP1-0.54-0.61
GOLGA2-0.54-0.47
GRIPAP1-0.54-0.52
MPHOSPH8-0.53-0.61
NOM1-0.53-0.59
AEBP2-0.53-0.54
ANKRD11-0.52-0.55
SURF6-0.52-0.52

Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityIEAglutamate (GO term level: 7)-
GO:0005539glycosaminoglycan bindingTAS8827452 
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007155cell adhesionTAS8827452 
GO:0006508proteolysisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionNAS14718574 
GO:0005615extracellular spaceTAS8827452 

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
OSAWA TNF TARGETS 106All SZGR 2.0 genes in this pathway
MATSUDA NATURAL KILLER DIFFERENTIATION 475313All SZGR 2.0 genes in this pathway
HSIAO LIVER SPECIFIC GENES 244154All SZGR 2.0 genes in this pathway
SU LIVER 5532All SZGR 2.0 genes in this pathway
KONDO PROSTATE CANCER WITH H3K27ME3 19693All SZGR 2.0 genes in this pathway
BOCHKIS FOXA2 TARGETS 425261All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS CTNNB1 DN 170105All SZGR 2.0 genes in this pathway
COULOUARN TEMPORAL TGFB1 SIGNATURE DN 13899All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER SURVIVAL DN 11376All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA DN 267160All SZGR 2.0 genes in this pathway
SERVITJA LIVER HNF1A TARGETS DN 157105All SZGR 2.0 genes in this pathway
NABA ECM REGULATORS 238125All SZGR 2.0 genes in this pathway
NABA MATRISOME ASSOCIATED 753411All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028559All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-143113511421A,m8hsa-miR-143brainUGAGAUGAAGCACUGUAGCUCA
miR-186118511911Ahsa-miR-186CAAAGAAUUCUCCUUUUGGGCUU
miR-22410821088m8hsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
miR-3759299351Ahsa-miR-375UUUGUUCGUUCGGCUCGCGUGA