Gene Page: ZBTB48
Summary ?
GeneID | 3104 |
Symbol | ZBTB48 |
Synonyms | HKR3|ZNF855|pp9964 |
Description | zinc finger and BTB domain containing 48 |
Reference | MIM:165270|HGNC:HGNC:4930|Ensembl:ENSG00000204859|HPRD:01316|Vega:OTTHUMG00000001438 |
Gene type | protein-coding |
Map location | 1p36.3 |
Pascal p-value | 0.028 |
Sherlock p-value | 0.223 |
eGene | Nucleus accumbens basal ganglia |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
HLA-DPA1 | 0.93 | 0.93 |
CD74 | 0.88 | 0.90 |
HLA-DMB | 0.86 | 0.84 |
HLA-DMA | 0.86 | 0.83 |
HLA-DQA1 | 0.82 | 0.80 |
HLA-DRB1 | 0.79 | 0.84 |
EVI2B | 0.78 | 0.82 |
HLA-DPB1 | 0.76 | 0.84 |
TBXAS1 | 0.74 | 0.70 |
BLNK | 0.74 | 0.71 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
KIAA1949 | -0.53 | -0.72 |
SH3BP2 | -0.53 | -0.77 |
TUBB2B | -0.52 | -0.76 |
NKIRAS2 | -0.52 | -0.67 |
VAV2 | -0.51 | -0.71 |
ZNF551 | -0.51 | -0.65 |
AC004017.1 | -0.51 | -0.67 |
SH2B2 | -0.51 | -0.77 |
ZNF821 | -0.51 | -0.65 |
PCDHB18 | -0.50 | -0.66 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
ZHOU INFLAMMATORY RESPONSE LIVE DN | 384 | 220 | All SZGR 2.0 genes in this pathway |
THUM SYSTOLIC HEART FAILURE DN | 244 | 147 | All SZGR 2.0 genes in this pathway |
HUTTMANN B CLL POOR SURVIVAL UP | 276 | 187 | All SZGR 2.0 genes in this pathway |
LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
PEREZ TP53 TARGETS | 1174 | 695 | All SZGR 2.0 genes in this pathway |
WHITE NEUROBLASTOMA WITH 1P36.3 DELETION | 21 | 17 | All SZGR 2.0 genes in this pathway |
TSAI RESPONSE TO IONIZING RADIATION | 149 | 101 | All SZGR 2.0 genes in this pathway |
OKAWA NEUROBLASTOMA 1P36 31 DELETION | 22 | 19 | All SZGR 2.0 genes in this pathway |
TAVOR CEBPA TARGETS DN | 30 | 21 | All SZGR 2.0 genes in this pathway |
FAELT B CLL WITH VH3 21 UP | 44 | 30 | All SZGR 2.0 genes in this pathway |
SANSOM APC MYC TARGETS | 217 | 138 | All SZGR 2.0 genes in this pathway |
SANSOM APC TARGETS REQUIRE MYC | 210 | 123 | All SZGR 2.0 genes in this pathway |
ACEVEDO LIVER CANCER DN | 540 | 340 | All SZGR 2.0 genes in this pathway |
ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE DN | 274 | 165 | All SZGR 2.0 genes in this pathway |
MITSIADES RESPONSE TO APLIDIN UP | 439 | 257 | All SZGR 2.0 genes in this pathway |
CHEN METABOLIC SYNDROM NETWORK | 1210 | 725 | All SZGR 2.0 genes in this pathway |
MARTENS TRETINOIN RESPONSE DN | 841 | 431 | All SZGR 2.0 genes in this pathway |