Gene Page: DNAJB1

Summary
GeneID  3337
Symbol  DNAJB1
Synonyms  HSPF1|Hdj1|Hsp40|Sis1
Description  DnaJ (Hsp40) homolog, subfamily B, member 1
See related  HGNC:5270|MIM:604572|Ensembl:ENSG00000132002|HPRD:05198|
Locus tag  -
Gene type  protein-coding
Map location  19p13.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
NLGN10.770.52
TIAM20.770.52
SEMA3A0.750.52
LIMCH10.750.54
TGFBR10.750.55
AL590362.20.750.49
SORCS10.740.46
EML10.740.59
KCTD120.730.51
FAM59A0.730.58
Top 10 negatively co-expressed genes
TNFSF12-0.43-0.43
SERPINB6-0.43-0.40
PTH1R-0.40-0.45
AC007405.8-0.40-0.43
SLC9A3R2-0.40-0.36
SLC16A11-0.40-0.42
TMEM54-0.40-0.39
TSC22D4-0.40-0.48
C5orf53-0.40-0.45
HSD17B14-0.40-0.45
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0031072heat shock protein bindingIEA-
GO:0051082unfolded protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006457protein foldingIEA-
GO:0006986response to unfolded proteinTAS8975727 
GO:0051085chaperone cofactor-dependent protein foldingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CFTRABC35 | ABCC7 | CF | CFTR/MRP | MRP7 | TNR-CFTR | dJ760C5.1cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)Affinity Capture-WesternBioGRID10075921 
DNAJC3HP58 | P58 | P58IPK | PRKRIDnaJ (Hsp40) homolog, subfamily C, member 3-HPRD9920933 
FANCAFA | FA-H | FA1 | FAA | FACA | FAH | FANCH | MGC75158Fanconi anemia, complementation group ATwo-hybridBioGRID14499622 
HSF1HSTF1heat shock transcription factor 1-HPRD,BioGRID9499401 
HSPA1AFLJ54303 | FLJ54370 | FLJ54392 | FLJ54408 | FLJ75127 | HSP70-1 | HSP70-1A | HSP70I | HSP72 | HSPA1 | HSPA1Bheat shock 70kDa protein 1A-HPRD10593983 
HSPA4APG-2 | HS24/P52 | MGC131852 | RY | hsp70 | hsp70RYheat shock 70kDa protein 4Affinity Capture-Western
Reconstituted Complex		BioGRID14503850 
HSPA8HSC54 | HSC70 | HSC71 | HSP71 | HSP73 | HSPA10 | LAP1 | MGC131511 | MGC29929 | NIP71heat shock 70kDa protein 8Reconstituted ComplexBioGRID10075921 
Hsp40 interacts with the carboxy-terminal region of Hsc70.BIND10330192 
PTGES3P23 | TEBP | cPGESprostaglandin E synthase 3 (cytosolic)-HPRD11809754 
STUB1CHIP | HSPABP2 | NY-CO-7 | SDCCAG7 | UBOX1STIP1 homology and U-box containing protein 1-HPRD,BioGRID10330192 
TTC1FLJ46404 | TPR1tetratricopeptide repeat domain 1-HPRD14503850 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP 13680All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
NAGASHIMA_NRG1_SIGNALING_UP 176123All SZGR genes in this pathway
NAGASHIMA_EGF_SIGNALING_UP 5840All SZGR genes in this pathway
KIM_WT1_TARGETS_DN 459276All SZGR genes in this pathway
KIM_WT1_TARGETS_8HR_UP 164122All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_UP 162116All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP 239157All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
WANG_ESOPHAGUS_CANCER_VS_NORMAL_DN 10166All SZGR genes in this pathway
YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_DN 8748All SZGR genes in this pathway
WOOD_EBV_EBNA1_TARGETS_UP 11071All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
NAKAYAMA_FRA2_TARGETS 4327All SZGR genes in this pathway
CAFFAREL_RESPONSE_TO_THC_8HR_5_DN 118All SZGR genes in this pathway
SUH_COEXPRESSED_WITH_ID1_AND_ID2_UP 1914All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
MORI_SMALL_PRE_BII_LYMPHOCYTE_DN 7652All SZGR genes in this pathway
UEDA_CENTRAL_CLOCK 8862All SZGR genes in this pathway
MENSSEN_MYC_TARGETS 5335All SZGR genes in this pathway
PENG_GLUTAMINE_DEPRIVATION_DN 337230All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
GERY_CEBP_TARGETS 12690All SZGR genes in this pathway
GENTILE_UV_RESPONSE_CLUSTER_D9 2815All SZGR genes in this pathway
ZAMORA_NOS2_TARGETS_UP 6941All SZGR genes in this pathway
MARCHINI_TRABECTEDIN_RESISTANCE_UP 2116All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_8HR_UP 10573All SZGR genes in this pathway
CHIBA_RESPONSE_TO_TSA 5031All SZGR genes in this pathway
GERHOLD_ADIPOGENESIS_DN 6444All SZGR genes in this pathway
TAKAO_RESPONSE_TO_UVB_RADIATION_DN 9867All SZGR genes in this pathway
ZHENG_RESPONSE_TO_ARSENITE_UP 1814All SZGR genes in this pathway
BURTON_ADIPOGENESIS_PEAK_AT_2HR 5136All SZGR genes in this pathway
MCCLUNG_COCAIN_REWARD_4WK 7547All SZGR genes in this pathway
KYNG_RESPONSE_TO_H2O2_VIA_ERCC6 179All SZGR genes in this pathway
VISALA_RESPONSE_TO_HEAT_SHOCK_AND_AGING_DN 1412All SZGR genes in this pathway
KYNG_RESPONSE_TO_H2O2 7142All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_DN 10567All SZGR genes in this pathway
HELLER_HDAC_TARGETS_DN 292189All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN 281179All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_UP 673430All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP 425298All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_UP 294199All SZGR genes in this pathway
PODAR_RESPONSE_TO_ADAPHOSTIN_UP 14798All SZGR genes in this pathway
QI_PLASMACYTOMA_UP 259185All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A5 7032All SZGR genes in this pathway
KYNG_RESPONSE_TO_H2O2_VIA_ERCC6_DN 4631All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_G2 182102All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_G2_M 216124All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1375525591A,m8hsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-1434975031Ahsa-miR-143brainUGAGAUGAAGCACUGUAGCUCA
miR-155114511521A,m8hsa-miR-155UUAAUGCUAAUCGUGAUAGGGG
miR-198318381A,m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-543121127m8hsa-miR-543AAACAUUCGCGGUGCACUUCU
miR-911121118m8hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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