Gene Page: C2orf74
Summary ?
| GeneID | 339804 |
| Symbol | C2orf74 |
| Synonyms | - |
| Description | chromosome 2 open reading frame 74 |
| Reference | HGNC:HGNC:34439|Ensembl:ENSG00000237651|Vega:OTTHUMG00000187090 |
| Gene type | protein-coding |
| Map location | 2p15 |
| Pascal p-value | 0.173 |
| Sherlock p-value | 6.327E-4 |
| Fetal beta | -1.554 |
| eGene | Myers' cis & trans Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs720201 | chr2 | 61376462 | C2orf74 | 339804 | 0 | cis | ||
| rs1665272 | chr2 | 61379285 | C2orf74 | 339804 | 0.03 | cis | ||
| rs1177309 | chr2 | 61385247 | C2orf74 | 339804 | 0.03 | cis | ||
| rs3889717 | chr2 | 61390790 | C2orf74 | 339804 | 0 | cis | ||
| rs777587 | chr2 | 61427674 | C2orf74 | 339804 | 0.04 | cis | ||
| rs7591772 | chr2 | 61462399 | C2orf74 | 339804 | 0.16 | cis | ||
| rs2694618 | chr2 | 61536983 | C2orf74 | 339804 | 0.09 | cis | ||
| rs720201 | chr2 | 61376462 | C2orf74 | 339804 | 0.12 | trans | ||
| rs3889717 | chr2 | 61390790 | C2orf74 | 339804 | 0.16 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| ZHOU INFLAMMATORY RESPONSE LIVE DN | 384 | 220 | All SZGR 2.0 genes in this pathway |
| ZHOU INFLAMMATORY RESPONSE FIMA DN | 284 | 156 | All SZGR 2.0 genes in this pathway |