Gene Page: IFNA1
Summary ?
GeneID | 3439 |
Symbol | IFNA1 |
Synonyms | IFL|IFN|IFN-ALPHA|IFN-alphaD|IFNA13|IFNA@ |
Description | interferon, alpha 1 |
Reference | MIM:147660|HGNC:HGNC:5417|Ensembl:ENSG00000197919|HPRD:00974|Vega:OTTHUMG00000019673 |
Gene type | protein-coding |
Map location | 9p22 |
Pascal p-value | 0.014 |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)

Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
PSPH | 0.70 | 0.51 |
PHF11 | 0.69 | 0.53 |
PRCP | 0.69 | 0.47 |
SELT | 0.68 | 0.60 |
C1QB | 0.68 | 0.43 |
RAB9A | 0.67 | 0.46 |
GPR183 | 0.67 | 0.40 |
CRBN | 0.67 | 0.59 |
GLO1 | 0.66 | 0.57 |
TMEM165 | 0.66 | 0.56 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
C9orf131 | -0.34 | -0.32 |
CRIPAK | -0.33 | -0.36 |
AC010327.3 | -0.31 | -0.32 |
RP11-274B21.1 | -0.31 | -0.32 |
DMPK | -0.30 | -0.32 |
SLC29A4 | -0.30 | -0.29 |
DUOX1 | -0.30 | -0.35 |
AC104115.1 | -0.30 | -0.33 |
CEP250 | -0.30 | -0.24 |
TIAF1 | -0.30 | -0.24 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION | 267 | 161 | All SZGR 2.0 genes in this pathway |
KEGG REGULATION OF AUTOPHAGY | 35 | 30 | All SZGR 2.0 genes in this pathway |
KEGG ANTIGEN PROCESSING AND PRESENTATION | 89 | 65 | All SZGR 2.0 genes in this pathway |
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY | 102 | 88 | All SZGR 2.0 genes in this pathway |
KEGG RIG I LIKE RECEPTOR SIGNALING PATHWAY | 71 | 51 | All SZGR 2.0 genes in this pathway |
KEGG CYTOSOLIC DNA SENSING PATHWAY | 56 | 44 | All SZGR 2.0 genes in this pathway |
KEGG JAK STAT SIGNALING PATHWAY | 155 | 105 | All SZGR 2.0 genes in this pathway |
KEGG NATURAL KILLER CELL MEDIATED CYTOTOXICITY | 137 | 92 | All SZGR 2.0 genes in this pathway |
KEGG AUTOIMMUNE THYROID DISEASE | 53 | 49 | All SZGR 2.0 genes in this pathway |
BIOCARTA CYTOKINE PATHWAY | 22 | 16 | All SZGR 2.0 genes in this pathway |
BIOCARTA INFLAM PATHWAY | 29 | 24 | All SZGR 2.0 genes in this pathway |
BIOCARTA DC PATHWAY | 22 | 20 | All SZGR 2.0 genes in this pathway |
BIOCARTA IL1R PATHWAY | 33 | 29 | All SZGR 2.0 genes in this pathway |
PID CD8 TCR DOWNSTREAM PATHWAY | 65 | 56 | All SZGR 2.0 genes in this pathway |
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | 30 | 26 | All SZGR 2.0 genes in this pathway |
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | 132 | 101 | All SZGR 2.0 genes in this pathway |
REACTOME INTERFERON ALPHA BETA SIGNALING | 64 | 50 | All SZGR 2.0 genes in this pathway |
REACTOME REGULATION OF IFNA SIGNALING | 24 | 22 | All SZGR 2.0 genes in this pathway |
REACTOME INTERFERON SIGNALING | 159 | 116 | All SZGR 2.0 genes in this pathway |
REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS | 73 | 57 | All SZGR 2.0 genes in this pathway |
REACTOME HEMOSTASIS | 466 | 331 | All SZGR 2.0 genes in this pathway |
REACTOME INNATE IMMUNE SYSTEM | 279 | 178 | All SZGR 2.0 genes in this pathway |
REACTOME IMMUNE SYSTEM | 933 | 616 | All SZGR 2.0 genes in this pathway |
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM | 270 | 204 | All SZGR 2.0 genes in this pathway |
LEE CALORIE RESTRICTION NEOCORTEX UP | 83 | 66 | All SZGR 2.0 genes in this pathway |
LEE CALORIE RESTRICTION NEOCORTEX DN | 88 | 58 | All SZGR 2.0 genes in this pathway |
ACEVEDO LIVER CANCER WITH H3K27ME3 UP | 295 | 149 | All SZGR 2.0 genes in this pathway |
VART KSHV INFECTION ANGIOGENIC MARKERS UP | 165 | 118 | All SZGR 2.0 genes in this pathway |
NABA SECRETED FACTORS | 344 | 197 | All SZGR 2.0 genes in this pathway |
NABA MATRISOME ASSOCIATED | 753 | 411 | All SZGR 2.0 genes in this pathway |
NABA MATRISOME | 1028 | 559 | All SZGR 2.0 genes in this pathway |