Summary ?
GeneID3633
SymbolINPP5B
Synonyms5PTase
Descriptioninositol polyphosphate-5-phosphatase B
ReferenceMIM:147264|HGNC:HGNC:6077|Ensembl:ENSG00000204084|HPRD:00924|Vega:OTTHUMG00000004436
Gene typeprotein-coding
Map location1p34
Pascal p-value0.005
eGeneCaudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
ZNF518B0.970.98
PPP2R5E0.960.97
AP001011.30.960.96
LATS10.960.97
ZMYM20.960.97
ANKRD500.960.96
SCYL20.960.97
USP370.960.95
MED130.960.96
ZNF6990.950.96
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
FXYD1-0.73-0.88
AF347015.31-0.72-0.86
MT-CO2-0.71-0.88
AIFM3-0.71-0.76
TSC22D4-0.71-0.79
HSD17B14-0.70-0.79
HLA-F-0.70-0.76
S100B-0.70-0.81
AF347015.33-0.70-0.83
IFI27-0.69-0.85

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG INOSITOL PHOSPHATE METABOLISM 5442All SZGR 2.0 genes in this pathway
KEGG PHOSPHATIDYLINOSITOL SIGNALING SYSTEM 7656All SZGR 2.0 genes in this pathway
SLEBOS HEAD AND NECK CANCER WITH HPV UP 8443All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP 1142669All SZGR 2.0 genes in this pathway
GRAESSMANN RESPONSE TO MC AND DOXORUBICIN UP 612367All SZGR 2.0 genes in this pathway
PEREZ TP53 TARGETS 1174695All SZGR 2.0 genes in this pathway
LOPEZ MBD TARGETS 957597All SZGR 2.0 genes in this pathway
YE METASTATIC LIVER CANCER 2713All SZGR 2.0 genes in this pathway
VARELA ZMPSTE24 TARGETS DN 3818All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 12HR DN 10164All SZGR 2.0 genes in this pathway
MATZUK SPERMATOZOA 11477All SZGR 2.0 genes in this pathway
ELLWOOD MYC TARGETS DN 4027All SZGR 2.0 genes in this pathway
KESHELAVA MULTIPLE DRUG RESISTANCE 8856All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 4HR DN 254158All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 19721213All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY 1839928All SZGR 2.0 genes in this pathway