Gene Page: IPW
Summary ?
| GeneID | 3653 |
| Symbol | IPW |
| Synonyms | NCRNA00002 |
| Description | imprinted in Prader-Willi syndrome (non-protein coding) |
| Reference | MIM:601491|HGNC:HGNC:6109| |
| Gene type | ncRNA |
| Map location | 15q11.2 |
| Pascal p-value | 0.819 |
| Fetal beta | 0.105 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| CD93 | 0.76 | 0.77 |
| CD248 | 0.75 | 0.77 |
| COL4A1 | 0.73 | 0.74 |
| COL4A2 | 0.73 | 0.73 |
| HSPG2 | 0.72 | 0.71 |
| NID1 | 0.70 | 0.71 |
| FN1 | 0.69 | 0.67 |
| VASP | 0.69 | 0.73 |
| LAMC1 | 0.69 | 0.66 |
| ROBO4 | 0.68 | 0.73 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| C5orf53 | -0.46 | -0.53 |
| AC104794.1 | -0.43 | -0.51 |
| CA11 | -0.41 | -0.43 |
| ZBTB8OS | -0.41 | -0.46 |
| ABCC12 | -0.40 | -0.49 |
| COX7A1 | -0.40 | -0.50 |
| NPM2 | -0.40 | -0.42 |
| UQCRB | -0.40 | -0.47 |
| USMG5 | -0.40 | -0.53 |
| HSPB3 | -0.40 | -0.48 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER DN | 169 | 118 | All SZGR 2.0 genes in this pathway |
| GARY CD5 TARGETS DN | 431 | 263 | All SZGR 2.0 genes in this pathway |
| VECCHI GASTRIC CANCER EARLY DN | 367 | 220 | All SZGR 2.0 genes in this pathway |
| TIEN INTESTINE PROBIOTICS 24HR UP | 557 | 331 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 6HR UP | 953 | 554 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 24HR UP | 783 | 442 | All SZGR 2.0 genes in this pathway |
| SMID BREAST CANCER BASAL DN | 701 | 446 | All SZGR 2.0 genes in this pathway |
| CAIRO HEPATOBLASTOMA CLASSES UP | 605 | 377 | All SZGR 2.0 genes in this pathway |
| AZARE NEOPLASTIC TRANSFORMATION BY STAT3 UP | 121 | 70 | All SZGR 2.0 genes in this pathway |