Gene Page: IPW
Summary ?
GeneID | 3653 |
Symbol | IPW |
Synonyms | NCRNA00002 |
Description | imprinted in Prader-Willi syndrome (non-protein coding) |
Reference | MIM:601491|HGNC:HGNC:6109| |
Gene type | ncRNA |
Map location | 15q11.2 |
Pascal p-value | 0.819 |
Fetal beta | 0.105 |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS | |
PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
CD93 | 0.76 | 0.77 |
CD248 | 0.75 | 0.77 |
COL4A1 | 0.73 | 0.74 |
COL4A2 | 0.73 | 0.73 |
HSPG2 | 0.72 | 0.71 |
NID1 | 0.70 | 0.71 |
FN1 | 0.69 | 0.67 |
VASP | 0.69 | 0.73 |
LAMC1 | 0.69 | 0.66 |
ROBO4 | 0.68 | 0.73 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
C5orf53 | -0.46 | -0.53 |
AC104794.1 | -0.43 | -0.51 |
CA11 | -0.41 | -0.43 |
ZBTB8OS | -0.41 | -0.46 |
ABCC12 | -0.40 | -0.49 |
COX7A1 | -0.40 | -0.50 |
NPM2 | -0.40 | -0.42 |
UQCRB | -0.40 | -0.47 |
USMG5 | -0.40 | -0.53 |
HSPB3 | -0.40 | -0.48 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER DN | 169 | 118 | All SZGR 2.0 genes in this pathway |
GARY CD5 TARGETS DN | 431 | 263 | All SZGR 2.0 genes in this pathway |
VECCHI GASTRIC CANCER EARLY DN | 367 | 220 | All SZGR 2.0 genes in this pathway |
TIEN INTESTINE PROBIOTICS 24HR UP | 557 | 331 | All SZGR 2.0 genes in this pathway |
BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
KRIGE RESPONSE TO TOSEDOSTAT 6HR UP | 953 | 554 | All SZGR 2.0 genes in this pathway |
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP | 783 | 442 | All SZGR 2.0 genes in this pathway |
SMID BREAST CANCER BASAL DN | 701 | 446 | All SZGR 2.0 genes in this pathway |
CAIRO HEPATOBLASTOMA CLASSES UP | 605 | 377 | All SZGR 2.0 genes in this pathway |
AZARE NEOPLASTIC TRANSFORMATION BY STAT3 UP | 121 | 70 | All SZGR 2.0 genes in this pathway |