Gene Page: KMT5A
Summary ?
| GeneID | 387893 |
| Symbol | KMT5A |
| Synonyms | PR-Set7|SET07|SET8|SETD8 |
| Description | lysine methyltransferase 5A |
| Reference | MIM:607240|HGNC:HGNC:29489|Ensembl:ENSG00000183955|HPRD:06254|Vega:OTTHUMG00000150477 |
| Gene type | protein-coding |
| Map location | 12q24.31 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| LK:YES | Genome-wide Association Study | This data set included 99 genes mapped to the 22 regions. The 24 leading SNPs were also included in CV:Ripke_2013 |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs12997903 | chr2 | 1952083 | SETD8 | 387893 | 0.16 | trans | ||
| rs17029291 | chr3 | 32402138 | SETD8 | 387893 | 0.02 | trans | ||
| rs16838645 | chr4 | 6370354 | SETD8 | 387893 | 0.07 | trans | ||
| rs1324669 | chr13 | 107872446 | SETD8 | 387893 | 0.01 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.