Summary ?
GeneID4356
SymbolMPP3
SynonymsDLG3
Descriptionmembrane protein, palmitoylated 3
ReferenceMIM:601114|HGNC:HGNC:7221|Ensembl:ENSG00000161647|HPRD:03069|Vega:OTTHUMG00000133838
Gene typeprotein-coding
Map location17q21.31
Pascal p-value0.667
Fetal beta1.763
eGeneMyers' cis & trans
Meta
SupportPROTEIN CLUSTERING
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
Potential synaptic genes

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs6687849chr1175904808MPP343560.06trans
rs2481653chr1176044120MPP343560.08trans
rs2502827chr1176044216MPP343560.01trans
rs17572651chr1218943612MPP343560.19trans
rs17028363chr241913161MPP343560.16trans
rs16829545chr2151977407MPP343562.443E-25trans
rs16841750chr2158288461MPP343560.16trans
rs3845734chr2171125572MPP343565.073E-5trans
rs16863816chr2177292762MPP343560.12trans
rs7584986chr2184111432MPP343566.355E-10trans
rs9810143chr35060209MPP343560.05trans
rs7664496chr456252823MPP343560.18trans
rs504836chr456285304MPP343560.16trans
snp_a-20785690MPP343560.08trans
snp_a-18157710MPP343560.13trans
rs2183142chr4159232695MPP343565.48E-5trans
rs170776chr4173276735MPP343560.01trans
rs1396222chr4173279496MPP343560.01trans
rs335993chr4173321789MPP343560.02trans
rs335980chr4173329784MPP343560.01trans
rs335982chr4173330945MPP343560.03trans
rs336016chr4173366576MPP343560.12trans
rs10004745chr4173394996MPP343560.2trans
rs337984chr4173411662MPP343560.02trans
rs3111196chr554402889MPP343560.14trans
rs17762315chr576807576MPP343560.02trans
rs10491487chr580323367MPP343560trans
rs10474151chr584286402MPP343560.1trans
rs133604960MPP343560.17trans
rs12196880chr624313746MPP343560.09trans
rs10806988chr624341768MPP343560.04trans
rs9461864chr633481468MPP343560.01trans
rs16890367chr638078448MPP343566.097E-4trans
rs6996695chr877540580MPP343560.05trans
rs3118341chr925185518MPP343560trans
rs1126130chr925209346MPP343560.05trans
rs1998746chr925211761MPP343560.05trans
rs1332433chr925214440MPP343560.11trans
rs9406868chr925223372MPP343566.486E-4trans
rs11139334chr984209393MPP343561.892E-5trans
rs2766987chr9113667956MPP343560.15trans
rs1530404chr1364207519MPP343560.16trans
rs17289777chr1364223062MPP343560.16trans
rs9989228chr1437809252MPP343560.16trans
rs16955618chr1529937543MPP343561.067E-31trans
rs2077735chr1558479024MPP343560.02trans
rs9941296chr162759498MPP343560.13trans
rs16945437chr1711797650MPP343560.01trans
rs11873184chr181584081MPP343560trans
rs11882889chr1919887684MPP343560.14trans
rs749043chr2046995700MPP343560.02trans
rs1041786chr2122617710MPP343565.398E-7trans
rs16986332chrX10958354MPP343560.01trans
rs16990575chrX32691327MPP343560.01trans
rs16993189chrX144666166MPP343560.11trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
ZHOU INFLAMMATORY RESPONSE LIVE UP 485293All SZGR 2.0 genes in this pathway
THUM SYSTOLIC HEART FAILURE DN 244147All SZGR 2.0 genes in this pathway
DEURIG T CELL PROLYMPHOCYTIC LEUKEMIA UP 368234All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE FIMA UP 544308All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LPS UP 431237All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 2B 392251All SZGR 2.0 genes in this pathway
XU HGF TARGETS REPRESSED BY AKT1 DN 9558All SZGR 2.0 genes in this pathway
GRUETZMANN PANCREATIC CANCER UP 358245All SZGR 2.0 genes in this pathway
TARTE PLASMA CELL VS PLASMABLAST UP 398262All SZGR 2.0 genes in this pathway
MOREAUX MULTIPLE MYELOMA BY TACI UP 412249All SZGR 2.0 genes in this pathway
HOEGERKORP CD44 TARGETS TEMPORAL UP 138All SZGR 2.0 genes in this pathway
JOSEPH RESPONSE TO SODIUM BUTYRATE DN 6445All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 DN 830547All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE BY 4NQO 3824All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE UP 226164All SZGR 2.0 genes in this pathway
YOKOE CANCER TESTIS ANTIGENS 3822All SZGR 2.0 genes in this pathway
LIN NPAS4 TARGETS UP 163100All SZGR 2.0 genes in this pathway
YOSHIMURA MAPK8 TARGETS UP 1305895All SZGR 2.0 genes in this pathway
AGUIRRE PANCREATIC CANCER COPY NUMBER UP 298174All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE UP 857456All SZGR 2.0 genes in this pathway