Gene Page: ASMT

Summary ?
GeneID438
SymbolASMT
SynonymsASMTY|HIOMT|HIOMTY
Descriptionacetylserotonin O-methyltransferase
ReferenceMIM:300015|MIM:402500|HGNC:HGNC:750|Ensembl:ENSG00000196433|HPRD:02058|Vega:OTTHUMG00000021065
Gene typeprotein-coding
Map locationXp22.3 or Yp11.3
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs6688662chr176842132ASMT4380.19trans
rs512189chr1182632586ASMT4380.15trans
rs6666913chr1237092144ASMT4380trans
rs16865228chr26629622ASMT4380.1trans
rs16865230chr26630187ASMT4380.1trans
rs11691188chr26631799ASMT4380.1trans
rs10209546chr253408320ASMT4380.04trans
rs13403353chr2144067716ASMT4380trans
rs10195263chr2151725791ASMT4380.01trans
rs13413644chr2189475948ASMT4380.19trans
rs9855575chr315514062ASMT4380.14trans
rs6548978chr368139529ASMT4380.09trans
rs17011179chr373501887ASMT4380.18trans
rs7609917chr376094301ASMT4388.87E-5trans
rs2324466chr376100753ASMT4388.242E-7trans
rs17013713chr376105150ASMT4384.063E-6trans
rs17013722chr376107656ASMT4388.242E-7trans
rs17013724chr376107684ASMT4388.242E-7trans
rs16831155chr3173574763ASMT4380.1trans
rs11734196chr4102796071ASMT4380.04trans
rs10212684chr4102822506ASMT4380.01trans
rs9986296chr53199318ASMT4380.02trans
rs2895773chr5148114635ASMT4380trans
rs10059267chr5168676624ASMT4380.17trans
rs10078402chr5168678851ASMT4380.17trans
rs2281351chr6187343ASMT4380.12trans
rs7740062chr627705597ASMT4380.15trans
rs200470chr627762186ASMT4380.08trans
rs201005chr627804159ASMT4380.13trans
rs200955chr627839311ASMT4380.15trans
rs200959chr627842046ASMT4380.15trans
rs839777chr627909656ASMT4380.1trans
rs149898chr627958071ASMT4380.1trans
rs156742chr627963191ASMT4380.1trans
rs175955chr628059733ASMT4380.1trans
rs1225593chr628150518ASMT4380.1trans
rs195749chr637253745ASMT4380.07trans
rs16896683chr643687846ASMT4380.07trans
rs16875134chr685489519ASMT4380.05trans
rs16875178chr685516099ASMT4380.08trans
rs7808764chr710297264ASMT4380.11trans
rs17145334chr721808409ASMT4380.18trans
rs992435chr797050802ASMT4380.08trans
rs8190856chr818079123ASMT4380.1trans
rs16920368chr855392852ASMT4380.08trans
rs16927318chr862365911ASMT4380.01trans
rs348150chr873371619ASMT4380.04trans
rs16938220chr873377940ASMT4380.03trans
rs4545144chr8139689307ASMT4380.16trans
rs10815658chr97709422ASMT4380.02trans
rs17775722chr926199256ASMT4380.13trans
rs180038chr9101514415ASMT4380.01trans
rs4742740chr9101524552ASMT4380.01trans
rs4743277chr9101557528ASMT4380.02trans
rs11190152chr10101325914ASMT4380.17trans
rs2069410chr1256364644ASMT4381.604E-4trans
rs7979024chr1284506011ASMT4380.06trans
rs11105124chr1289375908ASMT4380.05trans
rs17834315chr1337991091ASMT4380trans
rs9542625chr1371811344ASMT4380.13trans
rs17091014chr1456562713ASMT4380.07trans
rs1743505chr1496143407ASMT4380.16trans
rs17142983chr167294508ASMT4380.11trans
rs6499075chr1666387395ASMT4380.13trans
rs8051077chr1675036432ASMT4380.18trans
rs17798004chr1870665382ASMT4380.11trans
rs17736134chr1870665805ASMT4380.09trans
rs2469060chr1870673106ASMT4380.09trans
rs2469009chr1870713334ASMT4380.16trans
rs65147590ASMT4380.01trans
rs409642chr2054250273ASMT4380.02trans
rs7290732chr2246691902ASMT4380.16trans
rs5920627chrX97385064ASMT4380.03trans
snp_a-20278250ASMT4380.02trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005184neuropeptide hormone activityIEAaxon, Synap, Brain, Neurotransmitter (GO term level: 6)-
GO:0017096acetylserotonin O-methyltransferase activityIEAserotonin (GO term level: 7)-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006412translationTAS8397829 
GO:0030187melatonin biosynthetic processIEA-
GO:0048511rhythmic processIEA-

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG TRYPTOPHAN METABOLISM 4033All SZGR 2.0 genes in this pathway
TARTE PLASMA CELL VS PLASMABLAST UP 398262All SZGR 2.0 genes in this pathway
ACEVEDO METHYLATED IN LIVER CANCER DN 940425All SZGR 2.0 genes in this pathway
TAVAZOIE METASTASIS 10868All SZGR 2.0 genes in this pathway