Gene Page: CCDC88C

Summary ?
GeneID440193
SymbolCCDC88C
SynonymsDAPLE|HKRP2|KIAA1509|SCA40
Descriptioncoiled-coil domain containing 88C
ReferenceMIM:611204|HGNC:HGNC:19967|Ensembl:ENSG00000015133|Vega:OTTHUMG00000171099
Gene typeprotein-coding
Map location14q32.11
Pascal p-value0.668
Sherlock p-value0.844
Fetal beta2.525
DMG1 (# studies)
eGeneMyers' cis & trans
Meta
SupportAscano FMRP targets

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Wockner_2014Genome-wide DNA methylation analysisThis dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg109285441491862864CCDC88C3.733E-4-0.6460.043DMG:Wockner_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs11160006chr1491890676CCDC88C4401930.12cis
rs10492950chr16006571CCDC88C4401930.01trans
rs7524578chr16056728CCDC88C4401930.09trans
rs16838771chr1157511227CCDC88C4401930.03trans
rs11943464chr423350098CCDC88C4401930.09trans
rs1491136chr4127646153CCDC88C4401930.1trans
rs1491137chr4127646180CCDC88C4401930.1trans
rs285146chr555735499CCDC88C4401930.15trans
rs474439chr5103137012CCDC88C4401930.18trans
rs7448080chr5123398097CCDC88C4401930.05trans
rs9397728chr6150514248CCDC88C4401930.19trans
rs16922710chr1023087297CCDC88C4401930.04trans
rs10508654chr1023104638CCDC88C4401930.01trans
rs7081986chr1090807242CCDC88C4401930.15trans
rs11018189chr10129345787CCDC88C4401930.11trans
rs11178165chr1270669547CCDC88C4401930.08trans
rs11178166chr1270670585CCDC88C4401930.08trans
rs443222chr1683889679CCDC88C4401930.01trans
rs824575chr1683891459CCDC88C4401930.01trans
rs16962554chr1929590544CCDC88C4401930trans
rs1883665chrX17650382CCDC88C4401930trans
rs7062071chrX17724830CCDC88C4401930.08trans
rs7879274chrX145592957CCDC88C4401930.01trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER UP 206111All SZGR 2.0 genes in this pathway
OSMAN BLADDER CANCER UP 404246All SZGR 2.0 genes in this pathway
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN 275168All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA UP 1821933All SZGR 2.0 genes in this pathway
LOPEZ MBD TARGETS 957597All SZGR 2.0 genes in this pathway
ROPERO HDAC2 TARGETS 11471All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR DN 428306All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 18HR DN 178121All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 UP 428266All SZGR 2.0 genes in this pathway
CADWELL ATG16L1 TARGETS DN 7043All SZGR 2.0 genes in this pathway
MEISSNER BRAIN HCP WITH H3K4ME3 AND H3K27ME3 1069729All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 19721213All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP A 898516All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE LATE 1137655All SZGR 2.0 genes in this pathway