Summary ?
GeneID51142
SymbolCHCHD2
SynonymsC7orf17|MNRR1|NS2TP|PARK22
Descriptioncoiled-coil-helix-coiled-coil-helix domain containing 2
ReferenceMIM:616244|HGNC:HGNC:21645|Ensembl:ENSG00000106153|HPRD:09879|Vega:OTTHUMG00000129429
Gene typeprotein-coding
Map location7p11.2
Pascal p-value0.004
Sherlock p-value0.238
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cerebellum
Cortex
Frontal Cortex BA9
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs112806668756084589CHCHD2ENSG00000106153.123.964E-7089680gtex_brain_ba24
rs117690775756085536CHCHD2ENSG00000106153.123.468E-7088733gtex_brain_ba24
rs73140778756089033CHCHD2ENSG00000106153.122.218E-7085236gtex_brain_ba24
rs113265498756093988CHCHD2ENSG00000106153.122.168E-7080281gtex_brain_ba24
rs59193297756096213CHCHD2ENSG00000106153.122.391E-7078056gtex_brain_ba24
rs6955615756098796CHCHD2ENSG00000106153.124.842E-7075473gtex_brain_ba24
rs6954669756098906CHCHD2ENSG00000106153.123.064E-7075363gtex_brain_ba24
rs7791221756104688CHCHD2ENSG00000106153.121.915E-7069581gtex_brain_ba24
rs111791854756106146CHCHD2ENSG00000106153.122.221E-7068123gtex_brain_ba24
rs112126471756106472CHCHD2ENSG00000106153.121.913E-7067797gtex_brain_ba24
rs59852874756115321CHCHD2ENSG00000106153.121.907E-7058948gtex_brain_ba24
rs7779821756119944CHCHD2ENSG00000106153.121.947E-7054325gtex_brain_ba24
rs7806994756139505CHCHD2ENSG00000106153.123.867E-7034764gtex_brain_ba24
rs58571234756145592CHCHD2ENSG00000106153.122.218E-7028677gtex_brain_ba24
rs17172508756149847CHCHD2ENSG00000106153.121.111E-7024422gtex_brain_ba24
rs67818657756150289CHCHD2ENSG00000106153.121.057E-7023980gtex_brain_ba24
rs2242508756151489CHCHD2ENSG00000106153.125.493E-7022780gtex_brain_ba24
rs112501056756155759CHCHD2ENSG00000106153.127.513E-8018510gtex_brain_ba24
rs3966180756161121CHCHD2ENSG00000106153.127.608E-8013148gtex_brain_ba24
rs6593298756171760CHCHD2ENSG00000106153.126.298E-802509gtex_brain_ba24
rs4948107756173407CHCHD2ENSG00000106153.126.412E-80862gtex_brain_ba24
rs4948108756173628CHCHD2ENSG00000106153.126.307E-80641gtex_brain_ba24
rs77036114756174351CHCHD2ENSG00000106153.126.317E-80-82gtex_brain_ba24
rs146847249756174353CHCHD2ENSG00000106153.126.317E-80-84gtex_brain_ba24
rs139238064756174551CHCHD2ENSG00000106153.126.327E-80-282gtex_brain_ba24
rs58230982756179661CHCHD2ENSG00000106153.124.289E-70-5392gtex_brain_ba24
rs2016580756184642CHCHD2ENSG00000106153.124.272E-70-10373gtex_brain_ba24
rs111872279756188381CHCHD2ENSG00000106153.126.298E-80-14112gtex_brain_ba24
rs2192262756191346CHCHD2ENSG00000106153.128.881E-70-17077gtex_brain_ba24
rs10499761756193643CHCHD2ENSG00000106153.126.298E-80-19374gtex_brain_ba24
rs114026903756193749CHCHD2ENSG00000106153.126.298E-80-19480gtex_brain_ba24
rs68051560756208694CHCHD2ENSG00000106153.126.298E-80-34425gtex_brain_ba24
rs816229756213300CHCHD2ENSG00000106153.121.29E-60-39031gtex_brain_ba24
rs113753484756215989CHCHD2ENSG00000106153.126.298E-80-41720gtex_brain_ba24
rs147656751756216973CHCHD2ENSG00000106153.126.298E-80-42704gtex_brain_ba24
rs112297703756217002CHCHD2ENSG00000106153.126.298E-80-42733gtex_brain_ba24
rs138912485756217098CHCHD2ENSG00000106153.126.298E-80-42829gtex_brain_ba24
rs137859570756217797CHCHD2ENSG00000106153.122.905E-70-43528gtex_brain_ba24
rs192877109756217893CHCHD2ENSG00000106153.121.022E-70-43624gtex_brain_ba24
rs184466809756218210CHCHD2ENSG00000106153.129.394E-70-43941gtex_brain_ba24
rs142506035756220257CHCHD2ENSG00000106153.127.267E-80-45988gtex_brain_ba24
rs112163901756220770CHCHD2ENSG00000106153.126.301E-80-46501gtex_brain_ba24
rs73132316756221684CHCHD2ENSG00000106153.126.299E-80-47415gtex_brain_ba24
rs73132319756222546CHCHD2ENSG00000106153.126.299E-80-48277gtex_brain_ba24
rs4947538756226044CHCHD2ENSG00000106153.126.298E-80-51775gtex_brain_ba24
rs73132333756226489CHCHD2ENSG00000106153.126.085E-80-52220gtex_brain_ba24
rs73132395756229873CHCHD2ENSG00000106153.126.298E-80-55604gtex_brain_ba24
rs73132398756230383CHCHD2ENSG00000106153.126.298E-80-56114gtex_brain_ba24
rs118063245756235731CHCHD2ENSG00000106153.126.323E-80-61462gtex_brain_ba24
rs114806057756235789CHCHD2ENSG00000106153.126.298E-80-61520gtex_brain_ba24
rs111211497756235887CHCHD2ENSG00000106153.126.308E-80-61618gtex_brain_ba24
rs111314085756236001CHCHD2ENSG00000106153.125.65E-70-61732gtex_brain_ba24
rs140328268756240882CHCHD2ENSG00000106153.126.298E-80-66613gtex_brain_ba24
rs73135709756243878CHCHD2ENSG00000106153.126.298E-80-69609gtex_brain_ba24
rs111814423756248053CHCHD2ENSG00000106153.126.409E-80-73784gtex_brain_ba24
rs7808466756248655CHCHD2ENSG00000106153.126.461E-80-74386gtex_brain_ba24
rs7781376756252234CHCHD2ENSG00000106153.126.988E-80-77965gtex_brain_ba24
rs113789714756265372CHCHD2ENSG00000106153.129.516E-80-91103gtex_brain_ba24
rs112907150756268881CHCHD2ENSG00000106153.129.516E-80-94612gtex_brain_ba24
rs144420256756269079CHCHD2ENSG00000106153.129.516E-80-94810gtex_brain_ba24
rs1524437756272698CHCHD2ENSG00000106153.129.516E-80-98429gtex_brain_ba24
rs73135752756273553CHCHD2ENSG00000106153.129.516E-80-99284gtex_brain_ba24
rs73135754756274522CHCHD2ENSG00000106153.129.516E-80-100253gtex_brain_ba24
rs73135756756274715CHCHD2ENSG00000106153.129.062E-80-100446gtex_brain_ba24
rs73135759756276677CHCHD2ENSG00000106153.129.525E-80-102408gtex_brain_ba24
rs73136191756279490CHCHD2ENSG00000106153.129.519E-80-105221gtex_brain_ba24
rs73136193756279509CHCHD2ENSG00000106153.129.513E-80-105240gtex_brain_ba24
rs66694283756279941CHCHD2ENSG00000106153.121.671E-70-105672gtex_brain_ba24
rs73136195756280610CHCHD2ENSG00000106153.129.516E-80-106341gtex_brain_ba24
rs73136197756280938CHCHD2ENSG00000106153.129.516E-80-106669gtex_brain_ba24
rs73138107756283341CHCHD2ENSG00000106153.129.516E-80-109072gtex_brain_ba24
rs73138108756283764CHCHD2ENSG00000106153.129.516E-80-109495gtex_brain_ba24
rs73138110756284017CHCHD2ENSG00000106153.129.516E-80-109748gtex_brain_ba24
rs73138118756287182CHCHD2ENSG00000106153.129.516E-80-112913gtex_brain_ba24
rs73138122756287623CHCHD2ENSG00000106153.129.516E-80-113354gtex_brain_ba24
rs73138130756290230CHCHD2ENSG00000106153.129.516E-80-115961gtex_brain_ba24
rs73138131756290498CHCHD2ENSG00000106153.129.516E-80-116229gtex_brain_ba24
rs73138133756290892CHCHD2ENSG00000106153.129.516E-80-116623gtex_brain_ba24
rs73138135756291862CHCHD2ENSG00000106153.129.516E-80-117593gtex_brain_ba24
rs1829963756295304CHCHD2ENSG00000106153.129.516E-80-121035gtex_brain_ba24
rs73140199756298323CHCHD2ENSG00000106153.129.516E-80-124054gtex_brain_ba24
rs73142116756301138CHCHD2ENSG00000106153.129.527E-80-126869gtex_brain_ba24
rs73142177756302425CHCHD2ENSG00000106153.129.547E-80-128156gtex_brain_ba24
rs73142188756304003CHCHD2ENSG00000106153.121.433E-60-129734gtex_brain_ba24
rs73142194756308710CHCHD2ENSG00000106153.121.292E-70-134441gtex_brain_ba24
rs7778744756309895CHCHD2ENSG00000106153.121.216E-70-135626gtex_brain_ba24
rs73142200756310523CHCHD2ENSG00000106153.121.226E-70-136254gtex_brain_ba24
rs73144003756311752CHCHD2ENSG00000106153.121.24E-70-137483gtex_brain_ba24

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
BLALOCK ALZHEIMERS DISEASE DN 1237837All SZGR 2.0 genes in this pathway
XU GH1 AUTOCRINE TARGETS UP 268157All SZGR 2.0 genes in this pathway
GAVIN FOXP3 TARGETS CLUSTER T7 9863All SZGR 2.0 genes in this pathway
GRADE COLON CANCER UP 871505All SZGR 2.0 genes in this pathway
GRADE COLON AND RECTAL CANCER UP 285167All SZGR 2.0 genes in this pathway
ALONSO METASTASIS UP 198128All SZGR 2.0 genes in this pathway
ROME INSULIN TARGETS IN MUSCLE UP 442263All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS UNANNOTATED DN 193112All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA CLASSES UP 605377All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE DN 841431All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 1 UP 12561All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 3 UP 17097All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 4 UP 11264All SZGR 2.0 genes in this pathway