Gene Page: GLTP
Summary ?
| GeneID | 51228 |
| Symbol | GLTP |
| Synonyms | - |
| Description | glycolipid transfer protein |
| Reference | MIM:608949|HGNC:HGNC:24867|Ensembl:ENSG00000139433|HPRD:16409|Vega:OTTHUMG00000169278 |
| Gene type | protein-coding |
| Map location | 12q24.11 |
| Pascal p-value | 0.001 |
| Sherlock p-value | 0.838 |
| eGene | Caudate basal ganglia Cerebellum Putamen basal ganglia |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs1055794 | 12 | 110290073 | GLTP | ENSG00000139433.5 | 1.359E-6 | 0.01 | 28220 | gtex_brain_putamen_basal |
| rs4766488 | 12 | 110296095 | GLTP | ENSG00000139433.5 | 1.984E-7 | 0.01 | 22198 | gtex_brain_putamen_basal |
| rs2193534 | 12 | 110297222 | GLTP | ENSG00000139433.5 | 3.883E-6 | 0.01 | 21071 | gtex_brain_putamen_basal |
| rs72359993 | 12 | 110297809 | GLTP | ENSG00000139433.5 | 5.75E-7 | 0.01 | 20484 | gtex_brain_putamen_basal |
| rs10850891 | 12 | 110299223 | GLTP | ENSG00000139433.5 | 1.984E-7 | 0.01 | 19070 | gtex_brain_putamen_basal |
| rs4766640 | 12 | 110300147 | GLTP | ENSG00000139433.5 | 5.048E-7 | 0.01 | 18146 | gtex_brain_putamen_basal |
| rs7955379 | 12 | 110301945 | GLTP | ENSG00000139433.5 | 1.018E-6 | 0.01 | 16348 | gtex_brain_putamen_basal |
| rs4766489 | 12 | 110306345 | GLTP | ENSG00000139433.5 | 7.513E-7 | 0.01 | 11948 | gtex_brain_putamen_basal |
| rs7397059 | 12 | 110310916 | GLTP | ENSG00000139433.5 | 9.977E-7 | 0.01 | 7377 | gtex_brain_putamen_basal |
| rs10850914 | 12 | 110312651 | GLTP | ENSG00000139433.5 | 9.977E-7 | 0.01 | 5642 | gtex_brain_putamen_basal |
| rs4766642 | 12 | 110313754 | GLTP | ENSG00000139433.5 | 1.984E-7 | 0.01 | 4539 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| GAZDA DIAMOND BLACKFAN ANEMIA ERYTHROID DN | 493 | 298 | All SZGR 2.0 genes in this pathway |
| FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP | 579 | 346 | All SZGR 2.0 genes in this pathway |
| HUMMERICH SKIN CANCER PROGRESSION UP | 88 | 58 | All SZGR 2.0 genes in this pathway |
| DAIRKEE TERT TARGETS UP | 380 | 213 | All SZGR 2.0 genes in this pathway |
| BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS | 882 | 572 | All SZGR 2.0 genes in this pathway |
| BILD HRAS ONCOGENIC SIGNATURE | 261 | 166 | All SZGR 2.0 genes in this pathway |
| CREIGHTON ENDOCRINE THERAPY RESISTANCE 5 | 482 | 296 | All SZGR 2.0 genes in this pathway |
| LEIN OLIGODENDROCYTE MARKERS | 74 | 53 | All SZGR 2.0 genes in this pathway |
| MASSARWEH TAMOXIFEN RESISTANCE UP | 578 | 341 | All SZGR 2.0 genes in this pathway |
| WALLACE PROSTATE CANCER RACE DN | 88 | 42 | All SZGR 2.0 genes in this pathway |
| BEIER GLIOMA STEM CELL DN | 66 | 42 | All SZGR 2.0 genes in this pathway |
| ICHIBA GRAFT VERSUS HOST DISEASE 35D UP | 131 | 79 | All SZGR 2.0 genes in this pathway |
| MILI PSEUDOPODIA CHEMOTAXIS UP | 74 | 45 | All SZGR 2.0 genes in this pathway |
| KASLER HDAC7 TARGETS 1 UP | 194 | 133 | All SZGR 2.0 genes in this pathway |
| GOBERT OLIGODENDROCYTE DIFFERENTIATION DN | 1080 | 713 | All SZGR 2.0 genes in this pathway |
| KRIEG HYPOXIA NOT VIA KDM3A | 770 | 480 | All SZGR 2.0 genes in this pathway |