Gene Page: TRAPPC2L
Summary ?
| GeneID | 51693 |
| Symbol | TRAPPC2L |
| Synonyms | HSPC176 |
| Description | trafficking protein particle complex 2-like |
| Reference | MIM:610970|HGNC:HGNC:30887|Ensembl:ENSG00000167515|HPRD:13711|Vega:OTTHUMG00000137861 |
| Gene type | protein-coding |
| Map location | 16q24.3 |
| Pascal p-value | 0.009 |
| eGene | Caudate basal ganglia Cerebellar Hemisphere Cerebellum Cortex Frontal Cortex BA9 Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Myers' cis & trans Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs7372527 | 0 | TRAPPC2L | 51693 | 0.07 | trans | |||
| rs9937138 | 16 | 88921022 | TRAPPC2L | ENSG00000167515.6 | 2.33E-9 | 0 | -2472 | gtex_brain_putamen_basal |
| rs12932588 | 16 | 88921493 | TRAPPC2L | ENSG00000167515.6 | 2.459E-9 | 0 | -2001 | gtex_brain_putamen_basal |
| rs34150867 | 16 | 88921634 | TRAPPC2L | ENSG00000167515.6 | 6.416E-8 | 0 | -1860 | gtex_brain_putamen_basal |
| rs113289677 | 16 | 88922989 | TRAPPC2L | ENSG00000167515.6 | 1.172E-10 | 0 | -505 | gtex_brain_putamen_basal |
| rs11076728 | 16 | 88925567 | TRAPPC2L | ENSG00000167515.6 | 1.45E-9 | 0 | 2073 | gtex_brain_putamen_basal |
| rs28656031 | 16 | 88927044 | TRAPPC2L | ENSG00000167515.6 | 1.328E-9 | 0 | 3550 | gtex_brain_putamen_basal |
| rs3826061 | 16 | 88927221 | TRAPPC2L | ENSG00000167515.6 | 1.9E-10 | 0 | 3727 | gtex_brain_putamen_basal |
| rs12597391 | 16 | 88928290 | TRAPPC2L | ENSG00000167515.6 | 1.642E-6 | 0 | 4796 | gtex_brain_putamen_basal |
| rs12596491 | 16 | 88928417 | TRAPPC2L | ENSG00000167515.6 | 5.14E-10 | 0 | 4923 | gtex_brain_putamen_basal |
| rs12921479 | 16 | 88929207 | TRAPPC2L | ENSG00000167515.6 | 6.965E-9 | 0 | 5713 | gtex_brain_putamen_basal |
| rs889753 | 16 | 88931914 | TRAPPC2L | ENSG00000167515.6 | 9.452E-7 | 0 | 8420 | gtex_brain_putamen_basal |
| rs12445058 | 16 | 88950025 | TRAPPC2L | ENSG00000167515.6 | 8.676E-7 | 0 | 26531 | gtex_brain_putamen_basal |
| rs12149315 | 16 | 88950302 | TRAPPC2L | ENSG00000167515.6 | 7.359E-7 | 0 | 26808 | gtex_brain_putamen_basal |
| rs11076730 | 16 | 88950685 | TRAPPC2L | ENSG00000167515.6 | 9.798E-7 | 0 | 27191 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP | 579 | 346 | All SZGR 2.0 genes in this pathway |
| TIEN INTESTINE PROBIOTICS 24HR UP | 557 | 331 | All SZGR 2.0 genes in this pathway |
| DAIRKEE TERT TARGETS UP | 380 | 213 | All SZGR 2.0 genes in this pathway |
| STARK PREFRONTAL CORTEX 22Q11 DELETION DN | 517 | 309 | All SZGR 2.0 genes in this pathway |
| NIKOLSKY BREAST CANCER 16Q24 AMPLICON | 53 | 38 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS LATE PROGENITOR | 544 | 307 | All SZGR 2.0 genes in this pathway |
| JIANG VHL TARGETS | 138 | 91 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 6HR DN | 911 | 527 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 24HR DN | 1011 | 592 | All SZGR 2.0 genes in this pathway |
| ACEVEDO LIVER CANCER DN | 540 | 340 | All SZGR 2.0 genes in this pathway |
| GRATIAS RETINOBLASTOMA 16Q24 | 17 | 15 | All SZGR 2.0 genes in this pathway |
| JIANG HYPOXIA VIA VHL | 34 | 24 | All SZGR 2.0 genes in this pathway |
| LI DCP2 BOUND MRNA | 89 | 57 | All SZGR 2.0 genes in this pathway |