Gene Page: PGGT1B
Summary ?
| GeneID | 5229 |
| Symbol | PGGT1B |
| Synonyms | BGGI|GGTI |
| Description | protein geranylgeranyltransferase type I subunit beta |
| Reference | MIM:602031|HGNC:HGNC:8895|Ensembl:ENSG00000164219|HPRD:03612|Vega:OTTHUMG00000128893 |
| Gene type | protein-coding |
| Map location | 5q22.3 |
| Pascal p-value | 0.049 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AES | 0.87 | 0.87 |
| ROGDI | 0.86 | 0.85 |
| APBB3 | 0.86 | 0.83 |
| B3GAT3 | 0.85 | 0.87 |
| WDR45 | 0.85 | 0.82 |
| NIT1 | 0.85 | 0.81 |
| MPI | 0.85 | 0.81 |
| MRPL4 | 0.84 | 0.82 |
| SLC25A11 | 0.84 | 0.79 |
| UQCRC1 | 0.84 | 0.80 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.18 | -0.56 | -0.38 |
| MT-ATP8 | -0.55 | -0.38 |
| AF347015.21 | -0.52 | -0.34 |
| AF347015.8 | -0.51 | -0.32 |
| AF347015.2 | -0.51 | -0.30 |
| MT-CYB | -0.49 | -0.32 |
| AL139819.3 | -0.48 | -0.42 |
| AF347015.26 | -0.48 | -0.30 |
| AF347015.15 | -0.47 | -0.30 |
| AF347015.31 | -0.47 | -0.30 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| LIU SOX4 TARGETS DN | 309 | 191 | All SZGR 2.0 genes in this pathway |
| CHARAFE BREAST CANCER LUMINAL VS BASAL UP | 380 | 215 | All SZGR 2.0 genes in this pathway |
| OSMAN BLADDER CANCER UP | 404 | 246 | All SZGR 2.0 genes in this pathway |
| SCHLOSSER SERUM RESPONSE DN | 712 | 443 | All SZGR 2.0 genes in this pathway |
| RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY DN | 382 | 224 | All SZGR 2.0 genes in this pathway |
| DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP | 314 | 201 | All SZGR 2.0 genes in this pathway |
| CUI TCF21 TARGETS 2 DN | 830 | 547 | All SZGR 2.0 genes in this pathway |
| MILI PSEUDOPODIA CHEMOTAXIS UP | 74 | 45 | All SZGR 2.0 genes in this pathway |
| WANG RECURRENT LIVER CANCER DN | 16 | 9 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 3 DN | 918 | 550 | All SZGR 2.0 genes in this pathway |
| BAKKER FOXO3 TARGETS UP | 61 | 41 | All SZGR 2.0 genes in this pathway |
| PURBEY TARGETS OF CTBP1 NOT SATB1 UP | 344 | 215 | All SZGR 2.0 genes in this pathway |
| RATTENBACHER BOUND BY CELF1 | 467 | 251 | All SZGR 2.0 genes in this pathway |