SZGR2

Summary ?

GeneID	5430
Symbol	POLR2A
Synonyms	POLR2\|POLRA\|RPB1\|RPBh1\|RPO2\|RPOL2\|RpIILS\|hRPB220\|hsRPB1
Description	polymerase (RNA) II subunit A
Reference	MIM:180660\|HGNC:HGNC:9187\|Ensembl:ENSG00000181222\|HPRD:08916\|Vega:OTTHUMG00000177594
Gene type	protein-coding
Map location	17p13.1
Pascal p-value	0.093
Sherlock p-value	0.992
Fetal beta	-1.195
Support	CompositeSet Darnell FMRP targets

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS
PMID:cooccur	High-throughput literature-search	Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature	High-throughput literature-search	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenics,schizophrenias	Click to show details

Section I. Genetics and epigenetics annotation

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
CHD3	0.74	0.67
ZNF462	0.73	0.64
BCL11A	0.73	0.63
UBTD2	0.72	0.67
MYST4	0.72	0.64
SMARCA4	0.72	0.67
AUTS2	0.71	0.67
ZNF860	0.71	0.60
MLLT4	0.71	0.64
GLB1L2	0.71	0.58

Top 10 negatively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
HLA-F	-0.55	-0.63
C5orf53	-0.54	-0.65
ALDOC	-0.54	-0.64
FBXO2	-0.53	-0.62
PTH1R	-0.53	-0.63
CLU	-0.53	-0.62
TNFSF12	-0.52	-0.60
AIFM3	-0.52	-0.64
TSC22D4	-0.52	-0.63
CSRP1	-0.52	-0.66

Section IV. Protein-protein interaction annotation

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ACTL6A	ACTL6 \| Arp4 \| BAF53A \| INO80K \| MGC5382	actin-like 6A	-	HPRD	9710619
BARD1	-	BRCA1 associated RING domain 1	-	HPRD	12154023
BRCA1	BRCAI \| BRCC1 \| IRIS \| PSCP \| RNF53	breast cancer 1, early onset	-	HPRD	4506230 \|9159119 \|12154023\|10725406
BRCA1	BRCAI \| BRCC1 \| IRIS \| PSCP \| RNF53	breast cancer 1, early onset	-	HPRD	4506230 \|9159119 \|12154023
BRCA1	BRCAI \| BRCC1 \| IRIS \| PSCP \| RNF53	breast cancer 1, early onset	Affinity Capture-Western Co-purification	BioGRID	9159119 \|11504724 \|12955082 \|14506230
C17orf56	FLJ31528	chromosome 17 open reading frame 56	-	HPRD	9710619
CCNC	CycC	cyclin C	-	HPRD,BioGRID	9443979
CCND1	BCL1 \| D11S287E \| PRAD1 \| U21B31	cyclin D1	Pol II interacts with cyclin D1 promoter.	BIND	15808510
CCNK	CPR4 \| MGC9113	cyclin K	Affinity Capture-Western in vitro	BioGRID	9632813 \|10574912
CCNL2	ANIA-6B \| CCNM \| DKFZp761A1210 \| DKFZp762O195 \| HCLA-ISO \| HLA-ISO \| PCEE \| SB138	cyclin L2	-	HPRD,BioGRID	14684736
CD82	4F9 \| C33 \| GR15 \| IA4 \| KAI1 \| R2 \| SAR2 \| ST6 \| TSPAN27	CD82 molecule	POLR2A (pol II) interacts with the CD82 (KAI1) promoter.	BIND	15829968
CDK8	K35 \| MGC126074 \| MGC126075	cyclin-dependent kinase 8	-	HPRD,BioGRID	9443979
CDK9	C-2k \| CDC2L4 \| CTK1 \| PITALRE \| TAK	cyclin-dependent kinase 9	CDK9 interacts with and phosphorylates POLR2A (RNAPII). This interaction was modelled on a demonstrated interaction between human CDK9 and POLR2A from an unspecified species.	BIND	12036313
CIITA	C2TA \| CIITAIV \| MHC2TA \| NLRA	class II, major histocompatibility complex, transactivator	Pol II interacts with p-MHC2TA.	BIND	15502823
CREBBP	CBP \| KAT3A \| RSTS	CREB binding protein	-	HPRD,BioGRID	9710619
CRKRS	CRK7 \| CRKR \| KIAA0904	Cdc2-related kinase, arginine/serine-rich	-	HPRD	11683387
CSH2	CS-2 \| CSB \| hCS-B	chorionic somatomammotropin hormone 2	-	HPRD,BioGRID	9312053 \|10944529
CTDP1	CCFDN \| FCP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	Affinity Capture-Western Co-purification Reconstituted Complex	BioGRID	9159119
CTDSP1	NLIIF \| SCP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	Biochemical Activity	BioGRID	12721286
CTDSP2	OS4 \| PSR2 \| SCP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	Biochemical Activity	BioGRID	12721286
DHX9	DDX9 \| LKP \| NDHII \| RHA	DEAH (Asp-Glu-Ala-His) box polypeptide 9	-	HPRD	11149922
DSCAM	CHD2-42 \| CHD2-52	Down syndrome cell adhesion molecule	Pol II interacts with DSCAM-1 enhancer.	BIND	16009131
EBAG9	EB9 \| PDAF \| RCAS1	estrogen receptor binding site associated, antigen, 9	Pol II interacts with EBAG9 promoter.	BIND	15808510
ELP3	FLJ10422 \| KAT9	elongation protein 3 homolog (S. cerevisiae)	Co-purification	BioGRID	11714725
EP300	KAT3B \| p300	E1A binding protein p300	Affinity Capture-Western Co-purification	BioGRID	9443979 \|9710619
FCP1	FCP \| FCPX	F-cell production 1	Reconstituted Complex	BioGRID	14576433
GTF2B	TF2B \| TFIIB	general transcription factor IIB	Co-purification Reconstituted Complex	BioGRID	9159119
GTF2E1	FE \| TF2E1 \| TFIIE-A	general transcription factor IIE, polypeptide 1, alpha 56kDa	Co-purification Reconstituted Complex	BioGRID	7926747 \|9159119
GTF2E2	FE \| TF2E2 \| TFIIE-B	general transcription factor IIE, polypeptide 2, beta 34kDa	Affinity Capture-Western	BioGRID	12665589
GTF2F1	BTF4 \| RAP74 \| TF2F1 \| TFIIF	general transcription factor IIF, polypeptide 1, 74kDa	Co-fractionation Co-purification Reconstituted Complex	BioGRID	9159119 \|9710619
GTF2F2	BTF4 \| RAP30 \| TF2F2 \| TFIIF	general transcription factor IIF, polypeptide 2, 30kDa	-	HPRD,BioGRID	3860504
GTF2H1	BTF2 \| TFB1 \| TFIIH	general transcription factor IIH, polypeptide 1, 62kDa	-	HPRD	9710619
GTF2H4	TFB2 \| TFIIH	general transcription factor IIH, polypeptide 4, 52kDa	Co-purification Reconstituted Complex	BioGRID	9159119
HBB	CD113t-C	hemoglobin, beta	Beta-globin interacts with pol II.	BIND	15565158
HES1	FLJ20408 \| HES-1 \| HHL \| HRY \| bHLHb39	hairy and enhancer of split 1, (Drosophila)	HES1 promoter interacts with RNAPII.	BIND	15546612
HNRNPU	HNRPU \| SAF-A \| U21.1	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	Affinity Capture-Western	BioGRID	10490622
HTATSF1	TAT-SF1 \| dJ196E23.2	HIV-1 Tat specific factor 1	Affinity Capture-Western	BioGRID	10454543
IFI6	6-16 \| FAM14C \| G1P3 \| IFI-6-16 \| IFI616	interferon, alpha-inducible protein 6	Pol II interacts with p-G1P3.	BIND	15502823
IL8	CXCL8 \| GCP-1 \| GCP1 \| LECT \| LUCT \| LYNAP \| MDNCF \| MONAP \| NAF \| NAP-1 \| NAP1	interleukin 8	The IL-8 promoter interacts with Pol II.	BIND	15494311
KAT2B	CAF \| P \| P/CAF \| PCAF	K(lysine) acetyltransferase 2B	Affinity Capture-Western	BioGRID	9710619
KLK2	KLK2A2 \| MGC12201 \| hK2	kallikrein-related peptidase 2	Pol II interacts with p-KLK-2.	BIND	15542435
KLK3	APS \| KLK2A1 \| PSA \| hK3	kallikrein-related peptidase 3	Pol II interacts with p-PSA.	BIND	15542435
MDC1	DKFZp781A0122 \| KIAA0170 \| MGC166888 \| NFBD1	mediator of DNA damage checkpoint 1	Protein-peptide	BioGRID	14578343
MED10	L6 \| MGC5309 \| NUT2 \| TRG20	mediator complex subunit 10	Affinity Capture-MS Affinity Capture-Western	BioGRID	15175163
MED19	DT2P1G7 \| LCMR1	mediator complex subunit 19	Affinity Capture-MS	BioGRID	15175163
MED21	SRB7 \| SURB7	mediator complex subunit 21	-	HPRD,BioGRID	9710619
MED26	CRSP7 \| CRSP70	mediator complex subunit 26	Affinity Capture-MS Affinity Capture-Western	BioGRID	15175163
MED28	1500003D12Rik \| DKFZp434N185 \| EG1 \| magicin	mediator complex subunit 28	Affinity Capture-MS	BioGRID	15175163
MED29	DKFZp434H247 \| IXL	mediator complex subunit 29	Affinity Capture-MS	BioGRID	15175163
MED9	FLJ10193 \| MED25 \| MGC138234	mediator complex subunit 9	Affinity Capture-MS	BioGRID	15175163
MYC	bHLHe39 \| c-Myc	v-myc myelocytomatosis viral oncogene homolog (avian)	Pol II interacts with c-myc promoter.	BIND	15808510
MYC	bHLHe39 \| c-Myc	v-myc myelocytomatosis viral oncogene homolog (avian)	Reconstituted Complex	BioGRID	12660246
NONO	NMT55 \| NRB54 \| P54 \| P54NRB	non-POU domain containing, octamer-binding	in vitro in vivo	BioGRID	12358429
NR0B2	FLJ17090 \| SHP \| SHP1	nuclear receptor subfamily 0, group B, member 2	Reconstituted Complex	BioGRID	12198243
NRIP1	FLJ77253 \| RIP140	nuclear receptor interacting protein 1	Pol II interacts with NRIP-1 enhancer.	BIND	16009131
PCIF1	C20orf67	PDX1 C-terminal inhibiting factor 1	Affinity Capture-Western Reconstituted Complex	BioGRID	12565871
PIN1	DOD \| UBL5	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	-	HPRD	10932246
PIN1	DOD \| UBL5	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	Affinity Capture-Western	BioGRID	10393805
POLR2C	RPB3 \| RPB31 \| hRPB33 \| hsRPB3	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	POLR2C (hRPB3) interacts with POLR2A (hRPB1).	BIND	9201987
POLR2C	RPB3 \| RPB31 \| hRPB33 \| hsRPB3	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	Reconstituted Complex	BioGRID	9201987
POLR2D	HSRBP4 \| HSRPB4 \| RBP4	polymerase (RNA) II (DNA directed) polypeptide D	hRPB4 interacts with hRPB1.	BIND	10567706
POLR2E	RPABC1 \| RPB5 \| XAP4 \| hRPB25 \| hsRPB5	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	POLR2E (hRPB5) interacts with POLR2A (hRPB1).	BIND	9201987
POLR2E	RPABC1 \| RPB5 \| XAP4 \| hRPB25 \| hsRPB5	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	Reconstituted Complex	BioGRID	9201987
POLR2F	HRBP14.4 \| POLRF \| RPABC2 \| RPB14.4 \| RPB6	polymerase (RNA) II (DNA directed) polypeptide F	Reconstituted Complex	BioGRID	9201987
POLR2G	MGC138367 \| MGC138369 \| RPB7 \| hRPB19 \| hsRPB7	polymerase (RNA) II (DNA directed) polypeptide G	Reconstituted Complex	BioGRID	9201987
POLR2G	MGC138367 \| MGC138369 \| RPB7 \| hRPB19 \| hsRPB7	polymerase (RNA) II (DNA directed) polypeptide G	POLR2G (hRPB7) interacts with POLR2A (hRPB1).	BIND	9201987
POLR2H	RPABC3 \| RPB17 \| RPB8 \| hsRPB8	polymerase (RNA) II (DNA directed) polypeptide H	Reconstituted Complex	BioGRID	9201987
POLR2H	RPABC3 \| RPB17 \| RPB8 \| hsRPB8	polymerase (RNA) II (DNA directed) polypeptide H	POLR2H (hRPB8) interacts with POLR2A (hRPB1).	BIND	9201987
POLR2H	RPABC3 \| RPB17 \| RPB8 \| hsRPB8	polymerase (RNA) II (DNA directed) polypeptide H	hRPB1 interacts with hRPB8.	BIND	10567706
POLR2K	ABC10-alpha \| RPABC4 \| RPB10alpha \| RPB12 \| RPB7.0 \| hRPB7.0 \| hsRPB10a	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	Reconstituted Complex	BioGRID	9201987
POLR2L	RBP10 \| RPABC5 \| RPB10 \| RPB10beta \| RPB7.6 \| hRPB7.6 \| hsRPB10b	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	POLR2L (hRPB10-beta) interacts with POLR2A (hRPB1).	BIND	9201987
POLR2L	RBP10 \| RPABC5 \| RPB10 \| RPB10beta \| RPB7.6 \| hRPB7.6 \| hsRPB10b	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	Reconstituted Complex	BioGRID	9201987
PPIG	CARS-Cyp \| CYP \| MGC133241 \| SRCyp	peptidylprolyl isomerase G (cyclophilin G)	-	HPRD,BioGRID	9153302
PPP1CC	PPP1G	protein phosphatase 1, catalytic subunit, gamma isoform	PPP1CC (TAPP) interacts with and dephosphorylates POLR2A (RNAPII). This interaction was modelled on a demonstrated interaction between human PPP1CC and POLR2A from an unspecified species.	BIND	12036313
RDBP	D6S45 \| NELF-E \| RD \| RDP	RD RNA binding protein	Affinity Capture-Western	BioGRID	12612062
SAFB	DKFZp779C1727 \| HAP \| HET \| SAFB1	scaffold attachment factor B	-	HPRD,BioGRID	9671816
SMARCA2	BAF190 \| BRM \| FLJ36757 \| MGC74511 \| SNF2 \| SNF2L2 \| SNF2LA \| SWI2 \| Sth1p \| hBRM \| hSNF2a	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	-	HPRD,BioGRID	9710619
SMARCA4	BAF190 \| BRG1 \| FLJ39786 \| SNF2 \| SNF2-BETA \| SNF2L4 \| SNF2LB \| SWI2 \| hSNF2b	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	Affinity Capture-Western Co-purification in vitro	BioGRID	8895581 \|9443979 \|9845365 \|11238380
SMARCA4	BAF190 \| BRG1 \| FLJ39786 \| SNF2 \| SNF2-BETA \| SNF2L4 \| SNF2LB \| SWI2 \| hSNF2b	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	-	HPRD	9443979 \|12154023
SMARCB1	BAF47 \| INI1 \| RDT \| SNF5 \| SNF5L1 \| Sfh1p \| Snr1 \| hSNFS	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	-	HPRD,BioGRID	9710619
SMARCC1	BAF155 \| CRACC1 \| Rsc8 \| SRG3 \| SWI3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	-	HPRD	9710619
SMARCC2	BAF170 \| CRACC2 \| Rsc8	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	-	HPRD	9710619
SMARCE1	BAF57	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	-	HPRD	9710619
SMYD3	FLJ21080 \| MGC104324 \| ZMYND1 \| ZNFN3A1 \| bA74P14.1	SET and MYND domain containing 3	Affinity Capture-Western	BioGRID	15235609
SND1	TDRD11 \| p100	staphylococcal nuclease and tudor domain containing 1	-	HPRD,BioGRID	12234934
SOD1	ALS \| ALS1 \| IPOA \| SOD \| homodimer	superoxide dismutase 1, soluble	Pol II interacts with SOD-1 enhancer.	BIND	16009131
SUPT5H	FLJ34157 \| SPT5 \| SPT5H	suppressor of Ty 5 homolog (S. cerevisiae)	Affinity Capture-Western	BioGRID	9450929 \|10454543
TAF10	TAF2A \| TAF2H \| TAFII30	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	-	HPRD	15099517
TAF11	MGC:15243 \| PRO2134 \| TAF2I \| TAFII28	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa	Co-purification Reconstituted Complex	BioGRID	9159119
TBP	GTF2D \| GTF2D1 \| MGC117320 \| MGC126054 \| MGC126055 \| SCA17 \| TFIID	TATA box binding protein	Co-purification Reconstituted Complex	BioGRID	9159119
TCEA1	GTF2S \| SII \| TCEA \| TF2S \| TFIIS	transcription elongation factor A (SII), 1	-	HPRD,BioGRID	12914699
TCERG1	CA150 \| MGC133200 \| TAF2S	transcription elongation regulator 1	-	HPRD,BioGRID	9315662 \|10908677
TFF1	BCEI \| D21S21 \| HP1.A \| HPS2 \| pNR-2 \| pS2	trefoil factor 1	PolII interacts with TFF-1 enhancer.	BIND	16009131
TFF1	BCEI \| D21S21 \| HP1.A \| HPS2 \| pNR-2 \| pS2	trefoil factor 1	PolII interacts with TFF-1 promoter.	BIND	16009131
TRAK1	OIP106	trafficking protein, kinesin binding 1	in vivo	BioGRID	12435728
TRAM2	KIAA0057	translocation associated membrane protein 2	-	HPRD	14612417
UPF1	FLJ43809 \| FLJ46894 \| HUPF1 \| KIAA0221 \| NORF1 \| RENT1 \| pNORF1	UPF1 regulator of nonsense transcripts homolog (yeast)	-	HPRD	6200476
WHSC2	FLJ10442 \| FLJ25112 \| NELF-A \| NELFA \| P/OKcl.15	Wolf-Hirschhorn syndrome candidate 2	Reconstituted Complex	BioGRID	12612062
XAB2	DKFZp762C1015 \| HCNP \| HCRN \| NTC90 \| SYF1	XPA binding protein 2	-	HPRD,BioGRID	10944529
XBP1	TREB5 \| XBP2	X-box binding protein 1	PolII interacts with XBP-1 enhancer.	BIND	16009131
ZNF74	Cos52 \| ZNF520 \| Zfp520	zinc finger protein 74	-	HPRD,BioGRID	9346935

Section V. Pathway annotation

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
KEGG PURINE METABOLISM	159	96	All SZGR 2.0 genes in this pathway
KEGG PYRIMIDINE METABOLISM	98	53	All SZGR 2.0 genes in this pathway
KEGG RNA POLYMERASE	29	12	All SZGR 2.0 genes in this pathway
KEGG HUNTINGTONS DISEASE	185	109	All SZGR 2.0 genes in this pathway
BIOCARTA CARM ER PATHWAY	35	27	All SZGR 2.0 genes in this pathway
BIOCARTA RARRXR PATHWAY	15	9	All SZGR 2.0 genes in this pathway
BIOCARTA DREAM PATHWAY	14	13	All SZGR 2.0 genes in this pathway
BIOCARTA TEL PATHWAY	18	15	All SZGR 2.0 genes in this pathway
REACTOME MICRORNA MIRNA BIOGENESIS	23	9	All SZGR 2.0 genes in this pathway
REACTOME REGULATORY RNA PATHWAYS	26	12	All SZGR 2.0 genes in this pathway
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	140	77	All SZGR 2.0 genes in this pathway
REACTOME RNA POL II TRANSCRIPTION	105	54	All SZGR 2.0 genes in this pathway
REACTOME MRNA CAPPING	30	11	All SZGR 2.0 genes in this pathway
REACTOME TRANSCRIPTION COUPLED NER TC NER	45	24	All SZGR 2.0 genes in this pathway
REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	41	21	All SZGR 2.0 genes in this pathway
REACTOME MRNA PROCESSING	161	86	All SZGR 2.0 genes in this pathway
REACTOME MRNA SPLICING	111	58	All SZGR 2.0 genes in this pathway
REACTOME MRNA SPLICING MINOR PATHWAY	45	19	All SZGR 2.0 genes in this pathway
REACTOME TRANSCRIPTION	210	127	All SZGR 2.0 genes in this pathway
REACTOME NUCLEOTIDE EXCISION REPAIR	51	27	All SZGR 2.0 genes in this pathway
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	45	19	All SZGR 2.0 genes in this pathway
REACTOME ELONGATION ARREST AND RECOVERY	32	14	All SZGR 2.0 genes in this pathway
REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	30	13	All SZGR 2.0 genes in this pathway
REACTOME DNA REPAIR	112	59	All SZGR 2.0 genes in this pathway
REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	61	32	All SZGR 2.0 genes in this pathway
REACTOME INFLUENZA LIFE CYCLE	203	72	All SZGR 2.0 genes in this pathway
REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	169	47	All SZGR 2.0 genes in this pathway
REACTOME HIV INFECTION	207	122	All SZGR 2.0 genes in this pathway
REACTOME HIV LIFE CYCLE	125	69	All SZGR 2.0 genes in this pathway
REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	23	7	All SZGR 2.0 genes in this pathway
REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	34	11	All SZGR 2.0 genes in this pathway
REACTOME LATE PHASE OF HIV LIFE CYCLE	104	61	All SZGR 2.0 genes in this pathway
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN	463	290	All SZGR 2.0 genes in this pathway
BOGNI TREATMENT RELATED MYELOID LEUKEMIA UP	30	19	All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA UP	1821	933	All SZGR 2.0 genes in this pathway
PROVENZANI METASTASIS UP	194	112	All SZGR 2.0 genes in this pathway
ENK UV RESPONSE KERATINOCYTE UP	530	342	All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP	1142	669	All SZGR 2.0 genes in this pathway
RASHI RESPONSE TO IONIZING RADIATION 3	48	31	All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 UP	309	199	All SZGR 2.0 genes in this pathway
SIMBULAN UV RESPONSE NORMAL DN	33	27	All SZGR 2.0 genes in this pathway
COLLIS PRKDC SUBSTRATES	20	15	All SZGR 2.0 genes in this pathway
FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK UP	87	58	All SZGR 2.0 genes in this pathway
LIN APC TARGETS	77	55	All SZGR 2.0 genes in this pathway
JECHLINGER EPITHELIAL TO MESENCHYMAL TRANSITION DN	66	47	All SZGR 2.0 genes in this pathway
JAZAERI BREAST CANCER BRCA1 VS BRCA2 DN	43	31	All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS STEM CELL	254	164	All SZGR 2.0 genes in this pathway
KIM GASTRIC CANCER CHEMOSENSITIVITY	103	64	All SZGR 2.0 genes in this pathway
SESTO RESPONSE TO UV C0	107	72	All SZGR 2.0 genes in this pathway
JACKSON DNMT1 TARGETS UP	77	57	All SZGR 2.0 genes in this pathway
DEBIASI APOPTOSIS BY REOVIRUS INFECTION DN	287	208	All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED	1229	713	All SZGR 2.0 genes in this pathway
MARSON BOUND BY E2F4 UNSTIMULATED	728	415	All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE BY GAMMA AND UV RADIATION	88	65	All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE UP	226	164	All SZGR 2.0 genes in this pathway
MARTINEZ RB1 TARGETS DN	543	317	All SZGR 2.0 genes in this pathway
MARTINEZ TP53 TARGETS DN	593	372	All SZGR 2.0 genes in this pathway
MARTINEZ RB1 AND TP53 TARGETS DN	591	366	All SZGR 2.0 genes in this pathway
MITSIADES RESPONSE TO APLIDIN UP	439	257	All SZGR 2.0 genes in this pathway
BHATI G2M ARREST BY 2METHOXYESTRADIOL UP	125	68	All SZGR 2.0 genes in this pathway
KYNG WERNER SYNDROM AND NORMAL AGING DN	225	124	All SZGR 2.0 genes in this pathway
KARLSSON TGFB1 TARGETS DN	207	139	All SZGR 2.0 genes in this pathway
GOBERT OLIGODENDROCYTE DIFFERENTIATION UP	570	339	All SZGR 2.0 genes in this pathway
ABRAMSON INTERACT WITH AIRE	45	33	All SZGR 2.0 genes in this pathway

Gene Page: POLR2A