Summary ?
GeneID54606
SymbolDDX56
SynonymsDDX21|DDX26|NOH61
DescriptionDEAD-box helicase 56
ReferenceMIM:608023|HGNC:HGNC:18193|Ensembl:ENSG00000136271|HPRD:12154|Vega:OTTHUMG00000129211
Gene typeprotein-coding
Map location7p13
Pascal p-value2.429E-5
Sherlock p-value0.833
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs16829545chr2151977407DDX56546060.04trans
rs16878317chr831657853DDX56546060.16trans
rs7020639chr971907868DDX56546060.14trans
rs16955618chr1529937543DDX56546068.836E-4trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section IV. Protein-protein interaction annotation

InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DHX37DDX37 | FLJ41974 | KIAA1517 | MGC2695 | MGC4322 | MGC46245DEAH (Asp-Glu-Ala-His) box polypeptide 37Affinity Capture-MSBioGRID17353931 
DHX57DDX57 | FLJ32861DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57Affinity Capture-MSBioGRID17353931 
FBLFIB | FLRN | RNU3IP1fibrillarinAffinity Capture-MSBioGRID17353931 
FTSJ3EPCS3 | FLJ20062FtsJ homolog 3 (E. coli)Affinity Capture-MSBioGRID17353931 
GNL2FLJ40906 | HUMAUANTIG | NGP1 | Ngp-1 | dJ423B22.6guanine nucleotide binding protein-like 2 (nucleolar)Affinity Capture-MSBioGRID17353931 
HIST1H2BCH2B.1 | H2B/l | H2BFL | MGC104246 | dJ221C16.3histone cluster 1, H2bcAffinity Capture-MSBioGRID17353931 
MRPL43MGC17989 | MGC48892 | bMRP36amitochondrial ribosomal protein L43Affinity Capture-MSBioGRID17353931 
MRPS14DJ262D12.2 | HSMRPS14 | MRP-S14mitochondrial ribosomal protein S14Affinity Capture-MSBioGRID17353931 
MRPS24HSPC335 | MRP-S24mitochondrial ribosomal protein S24Affinity Capture-MSBioGRID17353931 
MRPS25DKFZp313H0817 | FLJ00023 | MRP-S25 | RPMS25mitochondrial ribosomal protein S25Affinity Capture-MSBioGRID17353931 
MRPS34MGC2616 | MRP-S12 | MRP-S34 | MRPS12mitochondrial ribosomal protein S34Affinity Capture-MSBioGRID17353931 
MRPS5MRP-S5 | S5mtmitochondrial ribosomal protein S5Affinity Capture-MSBioGRID17353931 
MRPS9MRP-S9 | RPMS9 | S9mtmitochondrial ribosomal protein S9Affinity Capture-MSBioGRID17353931 
MYBBP1AFLJ37886 | P160 | PAP2MYB binding protein (P160) 1aAffinity Capture-MSBioGRID17353931 
RPL18A-ribosomal protein L18aAffinity Capture-MSBioGRID17353931 
RPL23AFLJ27455 | MDA20ribosomal protein L23aAffinity Capture-MSBioGRID17353931 
RPL26-ribosomal protein L26Affinity Capture-MSBioGRID17353931 
RPL29HIP | HUMRPL29 | MGC88589ribosomal protein L29Affinity Capture-MSBioGRID17353931 
RPL31MGC88191ribosomal protein L31Affinity Capture-MSBioGRID17353931 
RPL34MGC111005ribosomal protein L34Affinity Capture-MSBioGRID17353931 
RPL37DKFZp686G1699 | MGC99572ribosomal protein L37Affinity Capture-MSBioGRID17353931 
RPS11-ribosomal protein S11Affinity Capture-MSBioGRID17353931 
RPS16-ribosomal protein S16Affinity Capture-MSBioGRID17353931 
RPS29-ribosomal protein S29Affinity Capture-MSBioGRID17353931 
RPS3AFTE1 | MFTL | MGC23240ribosomal protein S3AAffinity Capture-MSBioGRID17353931 
RPS9-ribosomal protein S9Affinity Capture-MSBioGRID17353931 
RRP12DKFZp762P1116 | FLJ20231 | KIAA0690ribosomal RNA processing 12 homolog (S. cerevisiae)Affinity Capture-MSBioGRID17353931 
SRP14ALURBP | MGC14326signal recognition particle 14kDa (homologous Alu RNA binding protein)Affinity Capture-MSBioGRID17353931 
USP33KIAA1097 | MGC16868 | VDU1ubiquitin specific peptidase 33Two-hybridBioGRID16169070 


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
STARK PREFRONTAL CORTEX 22Q11 DELETION DN 517309All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS 882572All SZGR 2.0 genes in this pathway
ZHOU TNF SIGNALING 30MIN 5436All SZGR 2.0 genes in this pathway
LEE CALORIE RESTRICTION MUSCLE DN 5128All SZGR 2.0 genes in this pathway
CHENG IMPRINTED BY ESTRADIOL 11068All SZGR 2.0 genes in this pathway
WEST ADRENOCORTICAL CARCINOMA VS ADENOMA UP 2113All SZGR 2.0 genes in this pathway
FONTAINE FOLLICULAR THYROID ADENOMA UP 7543All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA CLASSES UP 605377All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE DN 841431All SZGR 2.0 genes in this pathway
LEE BMP2 TARGETS DN 882538All SZGR 2.0 genes in this pathway