Gene Page: SLC35F2
Summary ?
| GeneID | 54733 |
| Symbol | SLC35F2 |
| Synonyms | HSNOV1 |
| Description | solute carrier family 35 member F2 |
| Reference | HGNC:HGNC:23615|Ensembl:ENSG00000110660|HPRD:15377|Vega:OTTHUMG00000166366 |
| Gene type | protein-coding |
| Map location | 11q22.3 |
| Pascal p-value | 0.076 |
| Fetal beta | 2.56 |
| eGene | Caudate basal ganglia Cerebellar Hemisphere Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:GWAScat | Genome-wide Association Studies | This data set includes 560 SNPs associated with schizophrenia. A total of 486 genes were mapped to these SNPs within 50kb. | |
| CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| GSMA_I | Genome scan meta-analysis | Psr: 0.006 |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs13403353 | chr2 | 144067716 | SLC35F2 | 54733 | 0.09 | trans | ||
| rs11212366 | 11 | 107646430 | SLC35F2 | ENSG00000110660.10 | 4.94E-7 | 0 | 152589 | gtex_brain_putamen_basal |
| rs11212405 | 11 | 107712020 | SLC35F2 | ENSG00000110660.10 | 9.104E-13 | 0 | 86999 | gtex_brain_putamen_basal |
| rs12221840 | 11 | 107712430 | SLC35F2 | ENSG00000110660.10 | 2.425E-10 | 0 | 86589 | gtex_brain_putamen_basal |
| rs397957133 | 11 | 107715256 | SLC35F2 | ENSG00000110660.10 | 6.003E-9 | 0 | 83763 | gtex_brain_putamen_basal |
| rs4753819 | 11 | 107715569 | SLC35F2 | ENSG00000110660.10 | 2.293E-12 | 0 | 83450 | gtex_brain_putamen_basal |
| rs4753820 | 11 | 107715745 | SLC35F2 | ENSG00000110660.10 | 2.091E-9 | 0 | 83274 | gtex_brain_putamen_basal |
| rs12278174 | 11 | 107716112 | SLC35F2 | ENSG00000110660.10 | 8.194E-13 | 0 | 82907 | gtex_brain_putamen_basal |
| rs10890766 | 11 | 107716445 | SLC35F2 | ENSG00000110660.10 | 1.198E-8 | 0 | 82574 | gtex_brain_putamen_basal |
| rs10890767 | 11 | 107716611 | SLC35F2 | ENSG00000110660.10 | 7.13E-12 | 0 | 82408 | gtex_brain_putamen_basal |
| rs10890768 | 11 | 107716624 | SLC35F2 | ENSG00000110660.10 | 1.834E-11 | 0 | 82395 | gtex_brain_putamen_basal |
| rs10890769 | 11 | 107716874 | SLC35F2 | ENSG00000110660.10 | 2.293E-12 | 0 | 82145 | gtex_brain_putamen_basal |
| rs11212408 | 11 | 107717100 | SLC35F2 | ENSG00000110660.10 | 2.293E-12 | 0 | 81919 | gtex_brain_putamen_basal |
| rs58034440 | 11 | 107717642 | SLC35F2 | ENSG00000110660.10 | 3.876E-7 | 0 | 81377 | gtex_brain_putamen_basal |
| rs10890770 | 11 | 107718428 | SLC35F2 | ENSG00000110660.10 | 2.293E-12 | 0 | 80591 | gtex_brain_putamen_basal |
| rs10789638 | 11 | 107718486 | SLC35F2 | ENSG00000110660.10 | 9.074E-13 | 0 | 80533 | gtex_brain_putamen_basal |
| rs7949443 | 11 | 107719003 | SLC35F2 | ENSG00000110660.10 | 3.293E-12 | 0 | 80016 | gtex_brain_putamen_basal |
| rs7952723 | 11 | 107719329 | SLC35F2 | ENSG00000110660.10 | 5.331E-13 | 0 | 79690 | gtex_brain_putamen_basal |
| rs7102437 | 11 | 107720191 | SLC35F2 | ENSG00000110660.10 | 2.843E-12 | 0 | 78828 | gtex_brain_putamen_basal |
| rs7121733 | 11 | 107720226 | SLC35F2 | ENSG00000110660.10 | 6.835E-13 | 0 | 78793 | gtex_brain_putamen_basal |
| rs4753821 | 11 | 107720941 | SLC35F2 | ENSG00000110660.10 | 5.331E-13 | 0 | 78078 | gtex_brain_putamen_basal |
| rs12418609 | 11 | 107721506 | SLC35F2 | ENSG00000110660.10 | 9.638E-11 | 0 | 77513 | gtex_brain_putamen_basal |
| rs10431032 | 11 | 107721901 | SLC35F2 | ENSG00000110660.10 | 4.178E-11 | 0 | 77118 | gtex_brain_putamen_basal |
| rs4754264 | 11 | 107722540 | SLC35F2 | ENSG00000110660.10 | 7.789E-13 | 0 | 76479 | gtex_brain_putamen_basal |
| rs144667830 | 11 | 107723274 | SLC35F2 | ENSG00000110660.10 | 2.888E-10 | 0 | 75745 | gtex_brain_putamen_basal |
| rs36043913 | 11 | 107725168 | SLC35F2 | ENSG00000110660.10 | 6.593E-11 | 0 | 73851 | gtex_brain_putamen_basal |
| rs4754265 | 11 | 107725297 | SLC35F2 | ENSG00000110660.10 | 2.293E-12 | 0 | 73722 | gtex_brain_putamen_basal |
| rs7109214 | 11 | 107726716 | SLC35F2 | ENSG00000110660.10 | 1.456E-12 | 0 | 72303 | gtex_brain_putamen_basal |
| rs200993199 | 11 | 107726849 | SLC35F2 | ENSG00000110660.10 | 3.784E-12 | 0 | 72170 | gtex_brain_putamen_basal |
| rs59133662 | 11 | 107727631 | SLC35F2 | ENSG00000110660.10 | 1.472E-10 | 0 | 71388 | gtex_brain_putamen_basal |
| rs11607450 | 11 | 107727662 | SLC35F2 | ENSG00000110660.10 | 4.928E-12 | 0 | 71357 | gtex_brain_putamen_basal |
| rs11212410 | 11 | 107728008 | SLC35F2 | ENSG00000110660.10 | 1.109E-12 | 0 | 71011 | gtex_brain_putamen_basal |
| rs924859 | 11 | 107728430 | SLC35F2 | ENSG00000110660.10 | 1.056E-12 | 0 | 70589 | gtex_brain_putamen_basal |
| rs924860 | 11 | 107728662 | SLC35F2 | ENSG00000110660.10 | 1.039E-12 | 0 | 70357 | gtex_brain_putamen_basal |
| rs11380459 | 11 | 107729116 | SLC35F2 | ENSG00000110660.10 | 1.975E-11 | 0 | 69903 | gtex_brain_putamen_basal |
| rs11603959 | 11 | 107729126 | SLC35F2 | ENSG00000110660.10 | 2.276E-12 | 0 | 69893 | gtex_brain_putamen_basal |
| rs11603925 | 11 | 107729205 | SLC35F2 | ENSG00000110660.10 | 8.413E-13 | 0 | 69814 | gtex_brain_putamen_basal |
| rs3741065 | 11 | 107729561 | SLC35F2 | ENSG00000110660.10 | 9.563E-13 | 0 | 69458 | gtex_brain_putamen_basal |
| rs61906861 | 11 | 107730204 | SLC35F2 | ENSG00000110660.10 | 1.313E-11 | 0 | 68815 | gtex_brain_putamen_basal |
| rs4754267 | 11 | 107730904 | SLC35F2 | ENSG00000110660.10 | 4.953E-11 | 0 | 68115 | gtex_brain_putamen_basal |
| rs7104006 | 11 | 107732390 | SLC35F2 | ENSG00000110660.10 | 4.382E-11 | 0 | 66629 | gtex_brain_putamen_basal |
| rs7104117 | 11 | 107732391 | SLC35F2 | ENSG00000110660.10 | 4.382E-11 | 0 | 66628 | gtex_brain_putamen_basal |
| rs12417231 | 11 | 107733687 | SLC35F2 | ENSG00000110660.10 | 1.592E-10 | 0 | 65332 | gtex_brain_putamen_basal |
| rs59964095 | 11 | 107734961 | SLC35F2 | ENSG00000110660.10 | 3.683E-10 | 0 | 64058 | gtex_brain_putamen_basal |
| rs73005388 | 11 | 107734964 | SLC35F2 | ENSG00000110660.10 | 8.419E-9 | 0 | 64055 | gtex_brain_putamen_basal |
| rs56875439 | 11 | 107735081 | SLC35F2 | ENSG00000110660.10 | 1.29E-10 | 0 | 63938 | gtex_brain_putamen_basal |
| rs56139321 | 11 | 107735115 | SLC35F2 | ENSG00000110660.10 | 1.453E-10 | 0 | 63904 | gtex_brain_putamen_basal |
| rs55669117 | 11 | 107735150 | SLC35F2 | ENSG00000110660.10 | 1.453E-10 | 0 | 63869 | gtex_brain_putamen_basal |
| rs56218864 | 11 | 107735212 | SLC35F2 | ENSG00000110660.10 | 1.453E-10 | 0 | 63807 | gtex_brain_putamen_basal |
| rs11212411 | 11 | 107735502 | SLC35F2 | ENSG00000110660.10 | 1.483E-10 | 0 | 63517 | gtex_brain_putamen_basal |
| rs4754268 | 11 | 107736597 | SLC35F2 | ENSG00000110660.10 | 3.915E-11 | 0 | 62422 | gtex_brain_putamen_basal |
| rs4587695 | 11 | 107736863 | SLC35F2 | ENSG00000110660.10 | 1.891E-10 | 0 | 62156 | gtex_brain_putamen_basal |
| rs57705781 | 11 | 107737623 | SLC35F2 | ENSG00000110660.10 | 3.061E-10 | 0 | 61396 | gtex_brain_putamen_basal |
| rs61906905 | 11 | 107737762 | SLC35F2 | ENSG00000110660.10 | 3.86E-10 | 0 | 61257 | gtex_brain_putamen_basal |
| rs12417999 | 11 | 107737927 | SLC35F2 | ENSG00000110660.10 | 2.698E-10 | 0 | 61092 | gtex_brain_putamen_basal |
| rs12225825 | 11 | 107738546 | SLC35F2 | ENSG00000110660.10 | 1.551E-10 | 0 | 60473 | gtex_brain_putamen_basal |
| rs7111326 | 11 | 107739265 | SLC35F2 | ENSG00000110660.10 | 3.573E-9 | 0 | 59754 | gtex_brain_putamen_basal |
| rs7111327 | 11 | 107739269 | SLC35F2 | ENSG00000110660.10 | 3.568E-9 | 0 | 59750 | gtex_brain_putamen_basal |
| rs4754270 | 11 | 107740685 | SLC35F2 | ENSG00000110660.10 | 1.393E-9 | 0 | 58334 | gtex_brain_putamen_basal |
| rs73007259 | 11 | 107741216 | SLC35F2 | ENSG00000110660.10 | 1.395E-9 | 0 | 57803 | gtex_brain_putamen_basal |
| rs7946548 | 11 | 107742791 | SLC35F2 | ENSG00000110660.10 | 1.421E-9 | 0 | 56228 | gtex_brain_putamen_basal |
| rs11212414 | 11 | 107743155 | SLC35F2 | ENSG00000110660.10 | 2.606E-8 | 0 | 55864 | gtex_brain_putamen_basal |
| rs4466794 | 11 | 107743582 | SLC35F2 | ENSG00000110660.10 | 1.421E-9 | 0 | 55437 | gtex_brain_putamen_basal |
| rs11212416 | 11 | 107743594 | SLC35F2 | ENSG00000110660.10 | 1.421E-9 | 0 | 55425 | gtex_brain_putamen_basal |
| rs11212419 | 11 | 107744303 | SLC35F2 | ENSG00000110660.10 | 1.488E-9 | 0 | 54716 | gtex_brain_putamen_basal |
| rs4531430 | 11 | 107744769 | SLC35F2 | ENSG00000110660.10 | 1.543E-9 | 0 | 54250 | gtex_brain_putamen_basal |
| rs11212421 | 11 | 107745307 | SLC35F2 | ENSG00000110660.10 | 1.657E-9 | 0 | 53712 | gtex_brain_putamen_basal |
| rs11212422 | 11 | 107745475 | SLC35F2 | ENSG00000110660.10 | 1.199E-10 | 0 | 53544 | gtex_brain_putamen_basal |
| rs4469854 | 11 | 107745911 | SLC35F2 | ENSG00000110660.10 | 5.524E-10 | 0 | 53108 | gtex_brain_putamen_basal |
| rs112789137 | 11 | 107746313 | SLC35F2 | ENSG00000110660.10 | 3.943E-8 | 0 | 52706 | gtex_brain_putamen_basal |
| rs7481935 | 11 | 107746344 | SLC35F2 | ENSG00000110660.10 | 6.469E-10 | 0 | 52675 | gtex_brain_putamen_basal |
| rs7941501 | 11 | 107747025 | SLC35F2 | ENSG00000110660.10 | 7.016E-10 | 0 | 51994 | gtex_brain_putamen_basal |
| rs11212434 | 11 | 107784165 | SLC35F2 | ENSG00000110660.10 | 2.035E-6 | 0 | 14854 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0003674 | molecular_function | ND | - | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0008150 | biological_process | ND | - | |
| GO:0006810 | transport | IEA | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0005575 | cellular_component | ND | - | |
| GO:0016020 | membrane | IEA | - | |
| GO:0016021 | integral to membrane | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL UP | 285 | 181 | All SZGR 2.0 genes in this pathway |
| KINSEY TARGETS OF EWSR1 FLII FUSION UP | 1278 | 748 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA DN | 1375 | 806 | All SZGR 2.0 genes in this pathway |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
| NUYTTEN NIPP1 TARGETS UP | 769 | 437 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE INCIPIENT UP | 390 | 242 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR | 681 | 420 | All SZGR 2.0 genes in this pathway |
| STEIN ESRRA TARGETS RESPONSIVE TO ESTROGEN UP | 31 | 20 | All SZGR 2.0 genes in this pathway |
| RIGGI EWING SARCOMA PROGENITOR UP | 430 | 288 | All SZGR 2.0 genes in this pathway |
| ACEVEDO LIVER CANCER WITH H3K27ME3 UP | 295 | 149 | All SZGR 2.0 genes in this pathway |
| ACEVEDO LIVER CANCER WITH H3K9ME3 UP | 141 | 75 | All SZGR 2.0 genes in this pathway |
| BOYLAN MULTIPLE MYELOMA D UP | 89 | 62 | All SZGR 2.0 genes in this pathway |
| MEISSNER NPC HCP WITH H3K4ME3 AND H3K27ME3 | 142 | 103 | All SZGR 2.0 genes in this pathway |
| STEIN ESRRA TARGETS | 535 | 325 | All SZGR 2.0 genes in this pathway |
| ZHAN MULTIPLE MYELOMA MS DN | 46 | 24 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN NPC HCP WITH H3K4ME3 AND H3K27ME3 | 210 | 148 | All SZGR 2.0 genes in this pathway |
| MIYAGAWA TARGETS OF EWSR1 ETS FUSIONS UP | 259 | 159 | All SZGR 2.0 genes in this pathway |
| KOINUMA TARGETS OF SMAD2 OR SMAD3 | 824 | 528 | All SZGR 2.0 genes in this pathway |
| PEDERSEN METASTASIS BY ERBB2 ISOFORM 7 | 403 | 240 | All SZGR 2.0 genes in this pathway |
| DELACROIX RAR BOUND ES | 462 | 273 | All SZGR 2.0 genes in this pathway |
Section VI. microRNA annotation
| miRNA family | Target position | miRNA ID | miRNA seq | ||
|---|---|---|---|---|---|
| UTR start | UTR end | Match method | |||
| miR-496 | 1541 | 1547 | 1A | hsa-miR-496 | AUUACAUGGCCAAUCUC |
- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.