Summary ?
GeneID54757
SymbolFAM20A
SynonymsAI1G|AIGFS|FP2747
Descriptionfamily with sequence similarity 20 member A
ReferenceMIM:611062|HGNC:HGNC:23015|Ensembl:ENSG00000108950|HPRD:13296|
Gene typeprotein-coding
Map location17q24.2
Pascal p-value0.081
Fetal beta0.855
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DNM:Fromer_2014Whole Exome Sequencing analysisThis study reported a WES study of 623 schizophrenia trios, reporting DNMs using genomic DNA.

Section I. Genetics and epigenetics annotation

@DNM table

GeneChromosomePositionRefAltTranscriptAA changeMutation typeSiftCG46TraitStudy
FAM20Achr1766538296CTNM_001243746
NM_001276290
NM_017565
NR_027751
.
.
.
.
silent
intronic
silent
npcRNA
SchizophreniaDNM:Fromer_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs1531089chr1219542971FAM20A547570.09trans
rs1566993chr2117105059FAM20A547570.15trans
rs11893837chr2127494318FAM20A547570.05trans
rs17077856chr345504326FAM20A547570.1trans
rs1353401chr459902753FAM20A547570.06trans
snp_a-21587150FAM20A547570.06trans
rs17381134chr4157179855FAM20A547570.05trans
rs10050805chr530805352FAM20A547570.16trans
rs9381511chr612931447FAM20A547570.07trans
rs6455226chr667930295FAM20A547570.03trans
rs1159612chr1085329057FAM20A547570.01trans
rs10879027chr1270237156FAM20A547570.08trans
rs10492030chr12113460334FAM20A547570.04trans
rs10781905chr1324993573FAM20A547570.17trans
rs1216717chr1346871963FAM20A547570.06trans
rs16956620chr1531496513FAM20A547570.11trans
rs16958302chr1657647432FAM20A547570.03trans
rs6095741chr2048666589FAM20A547570trans
rs5915713chrX4077883FAM20A547576.512E-4trans
rs5991662chrX43335796FAM20A547570.15trans
rs1545676chrX93530472FAM20A547573.534E-4trans
rs242163chrX132311662FAM20A547570.01trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA UP 205140All SZGR 2.0 genes in this pathway
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN 463290All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY DN 367220All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS C UP 170114All SZGR 2.0 genes in this pathway
NUYTTEN NIPP1 TARGETS DN 848527All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 17Q21 Q25 AMPLICON 335181All SZGR 2.0 genes in this pathway
BROWN MYELOID CELL DEVELOPMENT DN 12986All SZGR 2.0 genes in this pathway
GAVIN FOXP3 TARGETS CLUSTER P2 7955All SZGR 2.0 genes in this pathway
RAY TUMORIGENESIS BY ERBB2 CDC25A DN 159105All SZGR 2.0 genes in this pathway
VANTVEER BREAST CANCER ESR1 DN 240153All SZGR 2.0 genes in this pathway
MEISSNER NPC HCP WITH H3K4ME2 491319All SZGR 2.0 genes in this pathway
LI INDUCED T TO NATURAL KILLER UP 307182All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP B 549316All SZGR 2.0 genes in this pathway
LEE BMP2 TARGETS UP 745475All SZGR 2.0 genes in this pathway
WANG MLL TARGETS 289188All SZGR 2.0 genes in this pathway
DELACROIX RARG BOUND MEF 367231All SZGR 2.0 genes in this pathway
BOSCO TH1 CYTOTOXIC MODULE 11462All SZGR 2.0 genes in this pathway
DURAND STROMA S UP 297194All SZGR 2.0 genes in this pathway
GHANDHI DIRECT IRRADIATION UP 11068All SZGR 2.0 genes in this pathway
NABA ECM REGULATORS 238125All SZGR 2.0 genes in this pathway
NABA MATRISOME ASSOCIATED 753411All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028559All SZGR 2.0 genes in this pathway