Gene Page: CTSA

Summary
GeneID  5476
Symbol  CTSA
Synonyms  GLB2|GSL|NGBE|PPCA|PPGB
Description  cathepsin A
See related  HGNC:9251|MIM:256540|Ensembl:ENSG00000064601|HPRD:02020|
Locus tag  RP3-337O18.1
Gene type  protein-coding
Map location  20q13.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004185serine-type carboxypeptidase activityIEAglutamate (GO term level: 8)-
GO:0005515protein bindingIEA-
GO:0005515protein bindingIPI17353931 
GO:0008047enzyme activator activityTAS3107551 
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIEA-
GO:0006886intracellular protein transportTAS1387645 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005739mitochondrionIEA-
GO:0005764lysosomeNAS3136930 
GO:0005783endoplasmic reticulumTAS1387645 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CTNNBIP1ICAT | MGC15093catenin, beta interacting protein 1Affinity Capture-MSBioGRID17353931 
NEU1FLJ93471 | NANH | NEU | SIAL1sialidase 1 (lysosomal sialidase)Affinity Capture-Western
Co-fractionation		BioGRID9501080 
-HPRD3102233 |3922758 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_LYSOSOME 12183All SZGR genes in this pathway
KEGG_RENIN_ANGIOTENSIN_SYSTEM 1710All SZGR genes in this pathway
REACTOME_GLYCOSPHINGOLIPID_METABOLISM 3822All SZGR genes in this pathway
REACTOME_PHOSPHOLIPID_METABOLISM 198112All SZGR genes in this pathway
REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 9161All SZGR genes in this pathway
REACTOME_SPHINGOLIPID_METABOLISM 6940All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 478302All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM 539350All SZGR genes in this pathway
WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_UP 10867All SZGR genes in this pathway
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP 255177All SZGR genes in this pathway
BARRIER_COLON_CANCER_RECURRENCE_DN 2016All SZGR genes in this pathway
AKL_HTLV1_INFECTION_DN 6841All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_UP 380236All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP 418263All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN 378231All SZGR genes in this pathway
CREIGHTON_AKT1_SIGNALING_VIA_MTOR_DN 2316All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_DN 394258All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
AMUNDSON_RESPONSE_TO_ARSENITE 217143All SZGR genes in this pathway
WANG_HCP_PROSTATE_CANCER 11169All SZGR genes in this pathway
IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_DN 2114All SZGR genes in this pathway
NADLER_OBESITY_UP 6134All SZGR genes in this pathway
HASLINGER_B_CLL_WITH_13Q14_DELETION 2418All SZGR genes in this pathway
APPEL_IMATINIB_RESPONSE 3322All SZGR genes in this pathway
MARTINEZ_RESPONSE_TO_TRABECTEDIN_UP 7149All SZGR genes in this pathway
BURTON_ADIPOGENESIS_8 8657All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN 287208All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE 7750All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM 6647All SZGR genes in this pathway
RIGGINS_TAMOXIFEN_RESISTANCE_UP 6644All SZGR genes in this pathway
MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_DN 2413All SZGR genes in this pathway
RUIZ_TNC_TARGETS_UP 153107All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
JISON_SICKLE_CELL_DISEASE_UP 181106All SZGR genes in this pathway
RAGHAVACHARI_PLATELET_SPECIFIC_GENES 7046All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_DN 207139All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_UP 266142All SZGR genes in this pathway
NABA_ECM_REGULATORS 238125All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway


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