Gene Page: FAM118A
Summary ?
| GeneID | 55007 |
| Symbol | FAM118A |
| Synonyms | C22orf8 |
| Description | family with sequence similarity 118 member A |
| Reference | HGNC:HGNC:1313|Ensembl:ENSG00000100376|HPRD:07936|Vega:OTTHUMG00000151338 |
| Gene type | protein-coding |
| Map location | 22q13 |
| Pascal p-value | 0.527 |
| DMG | 1 (# studies) |
| eGene | Anterior cingulate cortex BA24 Caudate basal ganglia Cerebellar Hemisphere Cerebellum Cortex Frontal Cortex BA9 Hippocampus Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Myers' cis & trans Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| DMG:Wockner_2014 | Genome-wide DNA methylation analysis | This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). | 1 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
| Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| cg12262698 | 22 | 45704988 | FAM118A | 1.954E-4 | 0.457 | 0.035 | DMG:Wockner_2014 |
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs104664 | chr22 | 45711853 | FAM118A | 55007 | 0 | cis | ||
| rs3827393 | chr22 | 45736152 | FAM118A | 55007 | 0 | cis | ||
| rs6006992 | chr22 | 45742759 | FAM118A | 55007 | 0.01 | cis | ||
| rs136611 | chr22 | 45794282 | FAM118A | 55007 | 0.04 | cis | ||
| rs104664 | chr22 | 45711853 | FAM118A | 55007 | 0.09 | trans | ||
| rs3827393 | chr22 | 45736152 | FAM118A | 55007 | 0.08 | trans | ||
| rs12162930 | 0 | FAM118A | 55007 | 0.08 | trans | |||
| rs738169 | 22 | 45701732 | FAM118A | ENSG00000100376.7 | 9.491E-9 | 0 | -3117 | gtex_brain_ba24 |
| rs226502 | 22 | 45703444 | FAM118A | ENSG00000100376.7 | 8.722E-9 | 0 | -1405 | gtex_brain_ba24 |
| rs226503 | 22 | 45705241 | FAM118A | ENSG00000100376.7 | 2.599E-9 | 0 | 392 | gtex_brain_ba24 |
| rs104664 | 22 | 45711854 | FAM118A | ENSG00000100376.7 | 7.021E-9 | 0 | 7005 | gtex_brain_ba24 |
| rs226492 | 22 | 45714489 | FAM118A | ENSG00000100376.7 | 3.034E-7 | 0 | 9640 | gtex_brain_ba24 |
| rs2142552 | 22 | 45719497 | FAM118A | ENSG00000100376.7 | 5.706E-9 | 0 | 14648 | gtex_brain_ba24 |
| rs6006986 | 22 | 45723253 | FAM118A | ENSG00000100376.7 | 3.879E-7 | 0 | 18404 | gtex_brain_ba24 |
| rs6007590 | 22 | 45723584 | FAM118A | ENSG00000100376.7 | 3.905E-7 | 0 | 18735 | gtex_brain_ba24 |
| rs7285172 | 22 | 45726345 | FAM118A | ENSG00000100376.7 | 5.93E-9 | 0 | 21496 | gtex_brain_ba24 |
| rs6007595 | 22 | 45728978 | FAM118A | ENSG00000100376.7 | 1.506E-8 | 0 | 24129 | gtex_brain_ba24 |
| rs2350629 | 22 | 45731050 | FAM118A | ENSG00000100376.7 | 1.5E-8 | 0 | 26201 | gtex_brain_ba24 |
| rs738177 | 22 | 45731539 | FAM118A | ENSG00000100376.7 | 1.508E-8 | 0 | 26690 | gtex_brain_ba24 |
| rs3827393 | 22 | 45736153 | FAM118A | ENSG00000100376.7 | 1.6E-9 | 0 | 31304 | gtex_brain_ba24 |
| rs2350630 | 22 | 45736767 | FAM118A | ENSG00000100376.7 | 1.6E-9 | 0 | 31918 | gtex_brain_ba24 |
| rs6007602 | 22 | 45739322 | FAM118A | ENSG00000100376.7 | 1.6E-9 | 0 | 34473 | gtex_brain_ba24 |
| rs3747240 | 22 | 45740224 | FAM118A | ENSG00000100376.7 | 7.021E-9 | 0 | 35375 | gtex_brain_ba24 |
| rs9614647 | 22 | 45741718 | FAM118A | ENSG00000100376.7 | 1.6E-9 | 0 | 36869 | gtex_brain_ba24 |
| rs6006992 | 22 | 45742760 | FAM118A | ENSG00000100376.7 | 1.6E-9 | 0 | 37911 | gtex_brain_ba24 |
| rs6519844 | 22 | 45744423 | FAM118A | ENSG00000100376.7 | 1.975E-9 | 0 | 39574 | gtex_brain_ba24 |
| rs6006993 | 22 | 45744546 | FAM118A | ENSG00000100376.7 | 1.975E-9 | 0 | 39697 | gtex_brain_ba24 |
| rs8136319 | 22 | 45744854 | FAM118A | ENSG00000100376.7 | 4.76E-8 | 0 | 40005 | gtex_brain_ba24 |
| rs5765271 | 22 | 45746826 | FAM118A | ENSG00000100376.7 | 1.975E-9 | 0 | 41977 | gtex_brain_ba24 |
| rs5765272 | 22 | 45747901 | FAM118A | ENSG00000100376.7 | 7.422E-9 | 0 | 43052 | gtex_brain_ba24 |
| rs5765276 | 22 | 45748862 | FAM118A | ENSG00000100376.7 | 7.422E-9 | 0 | 44013 | gtex_brain_ba24 |
| rs1569413 | 22 | 45756081 | FAM118A | ENSG00000100376.7 | 1.6E-9 | 0 | 51232 | gtex_brain_ba24 |
| rs5764704 | 22 | 45757987 | FAM118A | ENSG00000100376.7 | 1.6E-9 | 0 | 53138 | gtex_brain_ba24 |
| . | 22 | 45759591 | FAM118A | ENSG00000100376.7 | 1.113E-8 | 0 | 54742 | gtex_brain_ba24 |
| rs136564 | 22 | 45764874 | FAM118A | ENSG00000100376.7 | 7.021E-9 | 0 | 60025 | gtex_brain_ba24 |
| rs136567 | 22 | 45766485 | FAM118A | ENSG00000100376.7 | 1.6E-9 | 0 | 61636 | gtex_brain_ba24 |
| rs136568 | 22 | 45766689 | FAM118A | ENSG00000100376.7 | 1.6E-9 | 0 | 61840 | gtex_brain_ba24 |
| rs470062 | 22 | 45767369 | FAM118A | ENSG00000100376.7 | 1.6E-9 | 0 | 62520 | gtex_brain_ba24 |
| rs136579 | 22 | 45771091 | FAM118A | ENSG00000100376.7 | 1.626E-8 | 0 | 66242 | gtex_brain_ba24 |
| rs5765304 | 22 | 45771974 | FAM118A | ENSG00000100376.7 | 1.626E-8 | 0 | 67125 | gtex_brain_ba24 |
| . | 22 | 45772596 | FAM118A | ENSG00000100376.7 | 2.385E-8 | 0 | 67747 | gtex_brain_ba24 |
| rs397831983 | 22 | 45774434 | FAM118A | ENSG00000100376.7 | 1.626E-8 | 0 | 69585 | gtex_brain_ba24 |
| rs136582 | 22 | 45774531 | FAM118A | ENSG00000100376.7 | 1.626E-8 | 0 | 69682 | gtex_brain_ba24 |
| rs136584 | 22 | 45776213 | FAM118A | ENSG00000100376.7 | 1.626E-8 | 0 | 71364 | gtex_brain_ba24 |
| rs369996523 | 22 | 45778523 | FAM118A | ENSG00000100376.7 | 1.626E-8 | 0 | 73674 | gtex_brain_ba24 |
| rs136589 | 22 | 45782142 | FAM118A | ENSG00000100376.7 | 1.626E-8 | 0 | 77293 | gtex_brain_ba24 |
| rs136592 | 22 | 45783722 | FAM118A | ENSG00000100376.7 | 1.626E-8 | 0 | 78873 | gtex_brain_ba24 |
| rs397726409 | 22 | 45783949 | FAM118A | ENSG00000100376.7 | 1.626E-8 | 0 | 79100 | gtex_brain_ba24 |
| rs5764719 | 22 | 45785847 | FAM118A | ENSG00000100376.7 | 1.626E-8 | 0 | 80998 | gtex_brain_ba24 |
| rs136599 | 22 | 45786514 | FAM118A | ENSG00000100376.7 | 1.626E-8 | 0 | 81665 | gtex_brain_ba24 |
| rs136601 | 22 | 45788098 | FAM118A | ENSG00000100376.7 | 1.6E-9 | 0 | 83249 | gtex_brain_ba24 |
| rs136604 | 22 | 45789743 | FAM118A | ENSG00000100376.7 | 1.605E-9 | 0 | 84894 | gtex_brain_ba24 |
| . | 22 | 45789845 | FAM118A | ENSG00000100376.7 | 1.632E-8 | 0 | 84996 | gtex_brain_ba24 |
| rs136606 | 22 | 45789974 | FAM118A | ENSG00000100376.7 | 1.632E-8 | 0 | 85125 | gtex_brain_ba24 |
| rs136608 | 22 | 45793131 | FAM118A | ENSG00000100376.7 | 1.608E-8 | 0 | 88282 | gtex_brain_ba24 |
| rs136610 | 22 | 45794212 | FAM118A | ENSG00000100376.7 | 1.603E-8 | 0 | 89363 | gtex_brain_ba24 |
| rs136611 | 22 | 45794283 | FAM118A | ENSG00000100376.7 | 1.603E-8 | 0 | 89434 | gtex_brain_ba24 |
| rs4605479 | 22 | 45797954 | FAM118A | ENSG00000100376.7 | 6.97E-9 | 0 | 93105 | gtex_brain_ba24 |
| rs5765327 | 22 | 45800926 | FAM118A | ENSG00000100376.7 | 1.583E-9 | 0 | 96077 | gtex_brain_ba24 |
| rs62231146 | 22 | 45807538 | FAM118A | ENSG00000100376.7 | 6.875E-9 | 0 | 102689 | gtex_brain_ba24 |
| rs12106522 | 22 | 45808036 | FAM118A | ENSG00000100376.7 | 1.588E-9 | 0 | 103187 | gtex_brain_ba24 |
| rs72619569 | 22 | 45808977 | FAM118A | ENSG00000100376.7 | 3.827E-8 | 0 | 104128 | gtex_brain_ba24 |
| rs4508710 | 22 | 45693443 | FAM118A | ENSG00000100376.7 | 1.255E-7 | 0 | -11406 | gtex_brain_putamen_basal |
| rs4823459 | 22 | 45693878 | FAM118A | ENSG00000100376.7 | 1.449E-7 | 0 | -10971 | gtex_brain_putamen_basal |
| rs226513 | 22 | 45697134 | FAM118A | ENSG00000100376.7 | 2.244E-9 | 0 | -7715 | gtex_brain_putamen_basal |
| rs170507 | 22 | 45698406 | FAM118A | ENSG00000100376.7 | 1.692E-11 | 0 | -6443 | gtex_brain_putamen_basal |
| rs738169 | 22 | 45701732 | FAM118A | ENSG00000100376.7 | 1.288E-17 | 0 | -3117 | gtex_brain_putamen_basal |
| rs226502 | 22 | 45703444 | FAM118A | ENSG00000100376.7 | 1.379E-17 | 0 | -1405 | gtex_brain_putamen_basal |
| rs226503 | 22 | 45705241 | FAM118A | ENSG00000100376.7 | 3.417E-18 | 0 | 392 | gtex_brain_putamen_basal |
| rs104664 | 22 | 45711854 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 7005 | gtex_brain_putamen_basal |
| rs170505 | 22 | 45713020 | FAM118A | ENSG00000100376.7 | 2.255E-16 | 0 | 8171 | gtex_brain_putamen_basal |
| rs226490 | 22 | 45713764 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 8915 | gtex_brain_putamen_basal |
| rs226492 | 22 | 45714489 | FAM118A | ENSG00000100376.7 | 3.372E-18 | 0 | 9640 | gtex_brain_putamen_basal |
| rs2142552 | 22 | 45719497 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 14648 | gtex_brain_putamen_basal |
| rs738171 | 22 | 45721284 | FAM118A | ENSG00000100376.7 | 1.242E-17 | 0 | 16435 | gtex_brain_putamen_basal |
| rs9614637 | 22 | 45722047 | FAM118A | ENSG00000100376.7 | 1.295E-17 | 0 | 17198 | gtex_brain_putamen_basal |
| rs79050799 | 22 | 45722753 | FAM118A | ENSG00000100376.7 | 1.546E-17 | 0 | 17904 | gtex_brain_putamen_basal |
| rs6006986 | 22 | 45723253 | FAM118A | ENSG00000100376.7 | 4.451E-18 | 0 | 18404 | gtex_brain_putamen_basal |
| rs5766654 | 22 | 45723465 | FAM118A | ENSG00000100376.7 | 1.413E-17 | 0 | 18616 | gtex_brain_putamen_basal |
| rs6007589 | 22 | 45723526 | FAM118A | ENSG00000100376.7 | 1.424E-17 | 0 | 18677 | gtex_brain_putamen_basal |
| rs6007590 | 22 | 45723584 | FAM118A | ENSG00000100376.7 | 4.58E-18 | 0 | 18735 | gtex_brain_putamen_basal |
| rs7285172 | 22 | 45726345 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 21496 | gtex_brain_putamen_basal |
| rs6007595 | 22 | 45728978 | FAM118A | ENSG00000100376.7 | 1.471E-16 | 0 | 24129 | gtex_brain_putamen_basal |
| rs2350629 | 22 | 45731050 | FAM118A | ENSG00000100376.7 | 1.479E-16 | 0 | 26201 | gtex_brain_putamen_basal |
| rs738177 | 22 | 45731539 | FAM118A | ENSG00000100376.7 | 3.871E-17 | 0 | 26690 | gtex_brain_putamen_basal |
| rs2205659 | 22 | 45731730 | FAM118A | ENSG00000100376.7 | 1.668E-14 | 0 | 26881 | gtex_brain_putamen_basal |
| rs2205660 | 22 | 45731731 | FAM118A | ENSG00000100376.7 | 1.569E-14 | 0 | 26882 | gtex_brain_putamen_basal |
| rs3827393 | 22 | 45736153 | FAM118A | ENSG00000100376.7 | 2.581E-18 | 0 | 31304 | gtex_brain_putamen_basal |
| rs2350630 | 22 | 45736767 | FAM118A | ENSG00000100376.7 | 2.581E-18 | 0 | 31918 | gtex_brain_putamen_basal |
| rs6007602 | 22 | 45739322 | FAM118A | ENSG00000100376.7 | 2.581E-18 | 0 | 34473 | gtex_brain_putamen_basal |
| rs3747240 | 22 | 45740224 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 35375 | gtex_brain_putamen_basal |
| rs9614647 | 22 | 45741718 | FAM118A | ENSG00000100376.7 | 2.581E-18 | 0 | 36869 | gtex_brain_putamen_basal |
| rs6006992 | 22 | 45742760 | FAM118A | ENSG00000100376.7 | 2.581E-18 | 0 | 37911 | gtex_brain_putamen_basal |
| rs6519844 | 22 | 45744423 | FAM118A | ENSG00000100376.7 | 2.842E-18 | 0 | 39574 | gtex_brain_putamen_basal |
| rs6006993 | 22 | 45744546 | FAM118A | ENSG00000100376.7 | 2.842E-18 | 0 | 39697 | gtex_brain_putamen_basal |
| rs8136319 | 22 | 45744854 | FAM118A | ENSG00000100376.7 | 1.425E-17 | 0 | 40005 | gtex_brain_putamen_basal |
| . | 22 | 45745336 | FAM118A | ENSG00000100376.7 | 2.657E-7 | 0 | 40487 | gtex_brain_putamen_basal |
| rs4823215 | 22 | 45745424 | FAM118A | ENSG00000100376.7 | 1.199E-6 | 0 | 40575 | gtex_brain_putamen_basal |
| rs4823217 | 22 | 45745437 | FAM118A | ENSG00000100376.7 | 1.01E-6 | 0 | 40588 | gtex_brain_putamen_basal |
| rs5765271 | 22 | 45746826 | FAM118A | ENSG00000100376.7 | 2.842E-18 | 0 | 41977 | gtex_brain_putamen_basal |
| rs5765272 | 22 | 45747901 | FAM118A | ENSG00000100376.7 | 9.532E-18 | 0 | 43052 | gtex_brain_putamen_basal |
| rs5765276 | 22 | 45748862 | FAM118A | ENSG00000100376.7 | 9.532E-18 | 0 | 44013 | gtex_brain_putamen_basal |
| rs1569413 | 22 | 45756081 | FAM118A | ENSG00000100376.7 | 2.581E-18 | 0 | 51232 | gtex_brain_putamen_basal |
| rs5764704 | 22 | 45757987 | FAM118A | ENSG00000100376.7 | 2.581E-18 | 0 | 53138 | gtex_brain_putamen_basal |
| . | 22 | 45759591 | FAM118A | ENSG00000100376.7 | 4.067E-14 | 0 | 54742 | gtex_brain_putamen_basal |
| rs136564 | 22 | 45764874 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 60025 | gtex_brain_putamen_basal |
| rs136567 | 22 | 45766485 | FAM118A | ENSG00000100376.7 | 2.581E-18 | 0 | 61636 | gtex_brain_putamen_basal |
| rs136568 | 22 | 45766689 | FAM118A | ENSG00000100376.7 | 2.581E-18 | 0 | 61840 | gtex_brain_putamen_basal |
| rs470062 | 22 | 45767369 | FAM118A | ENSG00000100376.7 | 2.581E-18 | 0 | 62520 | gtex_brain_putamen_basal |
| rs136579 | 22 | 45771091 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 66242 | gtex_brain_putamen_basal |
| rs5765304 | 22 | 45771974 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 67125 | gtex_brain_putamen_basal |
| . | 22 | 45772596 | FAM118A | ENSG00000100376.7 | 3.619E-14 | 0 | 67747 | gtex_brain_putamen_basal |
| rs397831983 | 22 | 45774434 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 69585 | gtex_brain_putamen_basal |
| rs136582 | 22 | 45774531 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 69682 | gtex_brain_putamen_basal |
| rs136584 | 22 | 45776213 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 71364 | gtex_brain_putamen_basal |
| rs369996523 | 22 | 45778523 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 73674 | gtex_brain_putamen_basal |
| rs136589 | 22 | 45782142 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 77293 | gtex_brain_putamen_basal |
| rs136592 | 22 | 45783722 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 78873 | gtex_brain_putamen_basal |
| rs397726409 | 22 | 45783949 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 79100 | gtex_brain_putamen_basal |
| rs5764719 | 22 | 45785847 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 80998 | gtex_brain_putamen_basal |
| rs136599 | 22 | 45786514 | FAM118A | ENSG00000100376.7 | 8.788E-18 | 0 | 81665 | gtex_brain_putamen_basal |
| rs136601 | 22 | 45788098 | FAM118A | ENSG00000100376.7 | 2.581E-18 | 0 | 83249 | gtex_brain_putamen_basal |
| rs136604 | 22 | 45789743 | FAM118A | ENSG00000100376.7 | 2.263E-16 | 0 | 84894 | gtex_brain_putamen_basal |
| . | 22 | 45789845 | FAM118A | ENSG00000100376.7 | 4.134E-16 | 0 | 84996 | gtex_brain_putamen_basal |
| rs136606 | 22 | 45789974 | FAM118A | ENSG00000100376.7 | 4.134E-16 | 0 | 85125 | gtex_brain_putamen_basal |
| rs136608 | 22 | 45793131 | FAM118A | ENSG00000100376.7 | 8.725E-18 | 0 | 88282 | gtex_brain_putamen_basal |
| rs136610 | 22 | 45794212 | FAM118A | ENSG00000100376.7 | 8.725E-18 | 0 | 89363 | gtex_brain_putamen_basal |
| rs136611 | 22 | 45794283 | FAM118A | ENSG00000100376.7 | 8.725E-18 | 0 | 89434 | gtex_brain_putamen_basal |
| rs4605479 | 22 | 45797954 | FAM118A | ENSG00000100376.7 | 8.725E-18 | 0 | 93105 | gtex_brain_putamen_basal |
| rs5765327 | 22 | 45800926 | FAM118A | ENSG00000100376.7 | 2.553E-18 | 0 | 96077 | gtex_brain_putamen_basal |
| rs62231146 | 22 | 45807538 | FAM118A | ENSG00000100376.7 | 9.822E-18 | 0 | 102689 | gtex_brain_putamen_basal |
| rs12106522 | 22 | 45808036 | FAM118A | ENSG00000100376.7 | 2.543E-18 | 0 | 103187 | gtex_brain_putamen_basal |
| rs72619569 | 22 | 45808977 | FAM118A | ENSG00000100376.7 | 4.652E-13 | 0 | 104128 | gtex_brain_putamen_basal |
| rs5764723 | 22 | 45813445 | FAM118A | ENSG00000100376.7 | 8.727E-11 | 0 | 108596 | gtex_brain_putamen_basal |
| rs62226841 | 22 | 45817454 | FAM118A | ENSG00000100376.7 | 1.982E-7 | 0 | 112605 | gtex_brain_putamen_basal |
| rs57537499 | 22 | 45819147 | FAM118A | ENSG00000100376.7 | 7.412E-7 | 0 | 114298 | gtex_brain_putamen_basal |
| rs1022479 | 22 | 45822347 | FAM118A | ENSG00000100376.7 | 7.252E-7 | 0 | 117498 | gtex_brain_putamen_basal |
| rs56144733 | 22 | 45832873 | FAM118A | ENSG00000100376.7 | 4.516E-8 | 0 | 128024 | gtex_brain_putamen_basal |
| rs62224962 | 22 | 45854696 | FAM118A | ENSG00000100376.7 | 8.508E-7 | 0 | 149847 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| LILRB3 | 0.73 | 0.63 |
| SLC37A2 | 0.48 | 0.31 |
| VSIG4 | 0.47 | 0.32 |
| CD14 | 0.47 | 0.29 |
| FCGR2A | 0.44 | 0.37 |
| SLC11A1 | 0.44 | 0.28 |
| FPR1 | 0.43 | 0.25 |
| CD68 | 0.43 | 0.30 |
| KLHL6 | 0.42 | 0.26 |
| HCK | 0.41 | 0.23 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| C5orf53 | -0.19 | -0.24 |
| SEC62 | -0.19 | -0.20 |
| UQCRB | -0.19 | -0.23 |
| C10orf4 | -0.18 | -0.21 |
| SYCP3 | -0.16 | -0.23 |
| RERGL | -0.16 | -0.18 |
| CD8BP | -0.15 | -0.14 |
| AC090772.4 | -0.15 | -0.23 |
| BXDC1 | -0.15 | -0.21 |
| AF347015.21 | -0.15 | -0.21 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL DN | 634 | 384 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION DN | 234 | 147 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN RESPONSE TO MC AND DOXORUBICIN DN | 770 | 415 | All SZGR 2.0 genes in this pathway |
| RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY UP | 236 | 139 | All SZGR 2.0 genes in this pathway |
| RICKMAN TUMOR DIFFERENTIATED WELL VS MODERATELY UP | 109 | 69 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 6HR UP | 953 | 554 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 24HR DN | 1011 | 592 | All SZGR 2.0 genes in this pathway |
| CHIANG LIVER CANCER SUBCLASS PROLIFERATION UP | 178 | 108 | All SZGR 2.0 genes in this pathway |
| KYNG WERNER SYNDROM AND NORMAL AGING UP | 93 | 62 | All SZGR 2.0 genes in this pathway |