Gene Page: MARCH1
Summary ?
GeneID | 55016 |
Symbol | MARCH1 |
Synonyms | MARCH-I|RNF171 |
Description | membrane associated ring-CH-type finger 1 |
Reference | MIM:613331|HGNC:HGNC:26077|Ensembl:ENSG00000145416|HPRD:07940|Vega:OTTHUMG00000161204 |
Gene type | protein-coding |
Map location | 4q32.2 |
Pascal p-value | 6.541E-4 |
eGene | Cerebellar Hemisphere Cerebellum |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
MFSD3 | 0.85 | 0.86 |
HAGH | 0.84 | 0.84 |
FAM3A | 0.83 | 0.80 |
OAZ1 | 0.82 | 0.82 |
C12orf52 | 0.82 | 0.87 |
PGP | 0.82 | 0.84 |
RPUSD3 | 0.82 | 0.79 |
DNAJC30 | 0.81 | 0.84 |
PIN1 | 0.81 | 0.81 |
TUSC2 | 0.81 | 0.82 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
EIF5B | -0.48 | -0.58 |
AC005921.3 | -0.44 | -0.61 |
AC010300.1 | -0.43 | -0.48 |
ZNF326 | -0.38 | -0.35 |
THOC2 | -0.38 | -0.35 |
RBM25 | -0.37 | -0.33 |
AF347015.18 | -0.37 | -0.17 |
SFRS18 | -0.37 | -0.47 |
RBMX2 | -0.37 | -0.42 |
ANP32C | -0.36 | -0.38 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN | 463 | 290 | All SZGR 2.0 genes in this pathway |
GARY CD5 TARGETS UP | 473 | 314 | All SZGR 2.0 genes in this pathway |
OSMAN BLADDER CANCER UP | 404 | 246 | All SZGR 2.0 genes in this pathway |
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 8D DN | 205 | 127 | All SZGR 2.0 genes in this pathway |
ZHOU INFLAMMATORY RESPONSE FIMA DN | 284 | 156 | All SZGR 2.0 genes in this pathway |
RODWELL AGING KIDNEY UP | 487 | 303 | All SZGR 2.0 genes in this pathway |
RIGGI EWING SARCOMA PROGENITOR UP | 430 | 288 | All SZGR 2.0 genes in this pathway |
TAVAZOIE METASTASIS | 108 | 68 | All SZGR 2.0 genes in this pathway |
MIKKELSEN ES ICP WITH H3K4ME3 AND H3K27ME3 | 137 | 85 | All SZGR 2.0 genes in this pathway |
JOHNSTONE PARVB TARGETS 3 DN | 918 | 550 | All SZGR 2.0 genes in this pathway |
PURBEY TARGETS OF CTBP1 NOT SATB1 UP | 344 | 215 | All SZGR 2.0 genes in this pathway |
PURBEY TARGETS OF CTBP1 NOT SATB1 DN | 448 | 282 | All SZGR 2.0 genes in this pathway |
RATTENBACHER BOUND BY CELF1 | 467 | 251 | All SZGR 2.0 genes in this pathway |