Gene Page: ACRV1
Summary ?
| GeneID | 56 |
| Symbol | ACRV1 |
| Synonyms | D11S4365|SP-10|SPACA2 |
| Description | acrosomal vesicle protein 1 |
| Reference | MIM:102525|HGNC:HGNC:127|Ensembl:ENSG00000134940|HPRD:00014|Vega:OTTHUMG00000165854 |
| Gene type | protein-coding |
| Map location | 11q24.2 |
| Pascal p-value | 0.022 |
| Sherlock p-value | 0.22 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| TAGLN | 0.91 | 0.93 |
| MYL9 | 0.91 | 0.92 |
| CNN1 | 0.90 | 0.88 |
| ACTG2 | 0.88 | 0.88 |
| AOC3 | 0.80 | 0.85 |
| ITIH3 | 0.79 | 0.72 |
| MYH11 | 0.78 | 0.85 |
| DES | 0.77 | 0.79 |
| MGP | 0.77 | 0.82 |
| LMOD1 | 0.77 | 0.81 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ZNF821 | -0.52 | -0.66 |
| MPP3 | -0.51 | -0.65 |
| ZNF311 | -0.51 | -0.63 |
| ZNF671 | -0.51 | -0.66 |
| C18orf22 | -0.51 | -0.65 |
| KIAA1949 | -0.51 | -0.59 |
| ZSCAN21 | -0.51 | -0.64 |
| TUBB2B | -0.51 | -0.61 |
| SETDB1 | -0.51 | -0.63 |
| ZNF836 | -0.51 | -0.65 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| DEURIG T CELL PROLYMPHOCYTIC LEUKEMIA UP | 368 | 234 | All SZGR 2.0 genes in this pathway |
| WANG CLIM2 TARGETS UP | 269 | 146 | All SZGR 2.0 genes in this pathway |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
| XU HGF TARGETS REPRESSED BY AKT1 DN | 95 | 58 | All SZGR 2.0 genes in this pathway |
| GRUETZMANN PANCREATIC CANCER DN | 203 | 134 | All SZGR 2.0 genes in this pathway |
| TARTE PLASMA CELL VS PLASMABLAST UP | 398 | 262 | All SZGR 2.0 genes in this pathway |
| MOREAUX MULTIPLE MYELOMA BY TACI UP | 412 | 249 | All SZGR 2.0 genes in this pathway |
| SU TESTIS | 76 | 53 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR | 681 | 420 | All SZGR 2.0 genes in this pathway |
| SHEDDEN LUNG CANCER GOOD SURVIVAL A12 | 317 | 177 | All SZGR 2.0 genes in this pathway |
| ACOSTA PROLIFERATION INDEPENDENT MYC TARGETS DN | 116 | 74 | All SZGR 2.0 genes in this pathway |
| ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL DN | 308 | 187 | All SZGR 2.0 genes in this pathway |