Gene Page: SEMA3G
Summary ?
| GeneID | 56920 |
| Symbol | SEMA3G |
| Synonyms | sem2 |
| Description | semaphorin 3G |
| Reference | HGNC:HGNC:30400|Ensembl:ENSG00000010319|HPRD:14251|Vega:OTTHUMG00000158570 |
| Gene type | protein-coding |
| Map location | 3p21.1 |
| Pascal p-value | 0.048 |
| Fetal beta | -0.967 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| LK:YES | Genome-wide Association Study | This data set included 99 genes mapped to the 22 regions. The 24 leading SNPs were also included in CV:Ripke_2013 |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs6687849 | chr1 | 175904808 | SEMA3G | 56920 | 0.01 | trans | ||
| rs2481653 | chr1 | 176044120 | SEMA3G | 56920 | 0.01 | trans | ||
| rs2502827 | chr1 | 176044216 | SEMA3G | 56920 | 0 | trans | ||
| rs12405921 | chr1 | 206695730 | SEMA3G | 56920 | 0.12 | trans | ||
| rs16829545 | chr2 | 151977407 | SEMA3G | 56920 | 9.543E-12 | trans | ||
| rs3845734 | chr2 | 171125572 | SEMA3G | 56920 | 6.508E-4 | trans | ||
| rs7584986 | chr2 | 184111432 | SEMA3G | 56920 | 4.73E-8 | trans | ||
| rs2183142 | chr4 | 159232695 | SEMA3G | 56920 | 0.13 | trans | ||
| rs3111196 | chr5 | 54402889 | SEMA3G | 56920 | 0.16 | trans | ||
| rs17762315 | chr5 | 76807576 | SEMA3G | 56920 | 0.04 | trans | ||
| rs6887062 | chr5 | 123850762 | SEMA3G | 56920 | 0.07 | trans | ||
| rs1368303 | chr5 | 147672388 | SEMA3G | 56920 | 0.17 | trans | ||
| rs11166603 | chr8 | 136578102 | SEMA3G | 56920 | 0.2 | trans | ||
| rs4075663 | chr11 | 18793398 | SEMA3G | 56920 | 0.14 | trans | ||
| rs4265582 | chr11 | 18797649 | SEMA3G | 56920 | 0.13 | trans | ||
| rs16955618 | chr15 | 29937543 | SEMA3G | 56920 | 9.348E-19 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG AXON GUIDANCE | 129 | 103 | All SZGR 2.0 genes in this pathway |
| DAIRKEE TERT TARGETS UP | 380 | 213 | All SZGR 2.0 genes in this pathway |
| SCHAEFFER PROSTATE DEVELOPMENT 6HR UP | 176 | 115 | All SZGR 2.0 genes in this pathway |
| CUI TCF21 TARGETS 2 DN | 830 | 547 | All SZGR 2.0 genes in this pathway |
| SMID BREAST CANCER BASAL DN | 701 | 446 | All SZGR 2.0 genes in this pathway |
| BOQUEST STEM CELL CULTURED VS FRESH UP | 425 | 298 | All SZGR 2.0 genes in this pathway |
| CHEN METABOLIC SYNDROM NETWORK | 1210 | 725 | All SZGR 2.0 genes in this pathway |
| NAKAYAMA SOFT TISSUE TUMORS PCA2 DN | 80 | 51 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |
| NABA ECM AFFILIATED | 171 | 89 | All SZGR 2.0 genes in this pathway |
| NABA MATRISOME ASSOCIATED | 753 | 411 | All SZGR 2.0 genes in this pathway |
| NABA MATRISOME | 1028 | 559 | All SZGR 2.0 genes in this pathway |