Gene Page: PRDM11
Summary ?
| GeneID | 56981 |
| Symbol | PRDM11 |
| Synonyms | PFM8 |
| Description | PR domain 11 |
| Reference | MIM:616347|HGNC:HGNC:13996|Ensembl:ENSG00000019485|HPRD:11456|Vega:OTTHUMG00000166478 |
| Gene type | protein-coding |
| Map location | 11p11 |
| Pascal p-value | 0.001 |
| Fetal beta | -0.238 |
| DMG | 2 (# studies) |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| DMG:Montano_2016 | Genome-wide DNA methylation analysis | This dataset includes 172 replicated associations between CpGs with schizophrenia. | 2 |
| DMG:Wockner_2014 | Genome-wide DNA methylation analysis | This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). | 2 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
| Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| cg00417304 | 11 | 45124456 | PRDM11 | 5.39E-6 | -0.009 | 0.03 | DMG:Montano_2016 |
| cg13300710 | 11 | 45167419 | PRDM11 | 6.39E-5 | -0.341 | 0.023 | DMG:Wockner_2014 |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.