Summary ?
GeneID57610
SymbolRANBP10
Synonyms-
DescriptionRAN binding protein 10
ReferenceMIM:614031|HGNC:HGNC:29285|Ensembl:ENSG00000141084|HPRD:15207|Vega:OTTHUMG00000184044
Gene typeprotein-coding
Map location16q22.1
Pascal p-value0.004
Sherlock p-value0.947
Fetal beta0.318
DMG1 (# studies)
eGeneCerebellum
Cortex
Myers' cis & trans
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Jaffe_2016Genome-wide DNA methylation analysisThis dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05. 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg013324031667840704RANBP106.58E-8-0.011.62E-5DMG:Jaffe_2016

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs12405921chr1206695730RANBP10576100.11trans
rs17572651chr1218943612RANBP10576100.09trans
rs16829545chr2151977407RANBP10576102.615E-11trans
rs16841750chr2158288461RANBP10576100.06trans
rs3845734chr2171125572RANBP10576101.594E-5trans
rs7584986chr2184111432RANBP10576102.37E-7trans
rs336544chr3161060557RANBP10576100.13trans
rs2183142chr4159232695RANBP10576100.15trans
rs170776chr4173276735RANBP10576100.13trans
rs1396222chr4173279496RANBP10576100.08trans
rs335980chr4173329784RANBP10576100.04trans
rs335982chr4173330945RANBP10576100.05trans
rs337984chr4173411662RANBP10576100.11trans
rs17762315chr576807576RANBP10576103.516E-4trans
rs3118341chr925185518RANBP10576100.02trans
rs2393316chr1059333070RANBP10576100.02trans
rs16955618chr1529937543RANBP10576105.532E-17trans
rs1041786chr2122617710RANBP10576102.176E-4trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
PID MET PATHWAY 8060All SZGR 2.0 genes in this pathway
LIU SOX4 TARGETS UP 13794All SZGR 2.0 genes in this pathway
BENPORATH NANOG TARGETS 988594All SZGR 2.0 genes in this pathway
BENPORATH SOX2 TARGETS 734436All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 STIMULATED 1022619All SZGR 2.0 genes in this pathway
FONTAINE FOLLICULAR THYROID ADENOMA UP 7543All SZGR 2.0 genes in this pathway
FONTAINE PAPILLARY THYROID CARCINOMA DN 8053All SZGR 2.0 genes in this pathway
LOPEZ TRANSLATION VIA FN1 SIGNALING 3521All SZGR 2.0 genes in this pathway