Summary ?
GeneID5763
SymbolPTMS
SynonymsParaT
Descriptionparathymosin
ReferenceMIM:168440|HGNC:HGNC:9629|Ensembl:ENSG00000159335|HPRD:01344|Vega:OTTHUMG00000169196
Gene typeprotein-coding
Map location12p13
Pascal p-value0.041
Sherlock p-value0.182
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs16854451chr3108039512PTMS57630.16trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
TGOLN20.920.94
PHLPP20.910.92
TTPAL0.900.91
SYT110.900.91
USP320.900.93
ATP2A20.890.91
ENTPD40.890.92
KCND30.880.93
GABBR20.880.84
TLN20.880.90
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AF347015.21-0.50-0.50
C1orf61-0.48-0.58
C1orf54-0.47-0.56
GNG11-0.46-0.50
HIGD1B-0.44-0.47
VAMP5-0.44-0.44
AP002478.3-0.44-0.47
DBI-0.44-0.52
SYCP3-0.43-0.51
PLA2G5-0.43-0.42

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KORKOLA TERATOMA UP 1611All SZGR 2.0 genes in this pathway
KORKOLA YOLK SAC TUMOR UP 2014All SZGR 2.0 genes in this pathway
GAL LEUKEMIC STEM CELL UP 13378All SZGR 2.0 genes in this pathway
RODRIGUES DCC TARGETS DN 12184All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 2 UP 418263All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN DN 17811082All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER HIGH RECURRENCE 4931All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 6HR DN 514330All SZGR 2.0 genes in this pathway
BENPORATH CYCLING GENES 648385All SZGR 2.0 genes in this pathway
KAUFFMANN DNA REPLICATION GENES 14787All SZGR 2.0 genes in this pathway
ZHOU TNF SIGNALING 30MIN 5436All SZGR 2.0 genes in this pathway
AMUNDSON POOR SURVIVAL AFTER GAMMA RADIATION 2G 17196All SZGR 2.0 genes in this pathway
ACEVEDO NORMAL TISSUE ADJACENT TO LIVER TUMOR DN 354216All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER DN 540340All SZGR 2.0 genes in this pathway
WHITFIELD CELL CYCLE M G1 14895All SZGR 2.0 genes in this pathway
LI INDUCED T TO NATURAL KILLER UP 307182All SZGR 2.0 genes in this pathway
HIRSCH CELLULAR TRANSFORMATION SIGNATURE DN 10367All SZGR 2.0 genes in this pathway
BILANGES SERUM AND RAPAMYCIN SENSITIVE GENES 6835All SZGR 2.0 genes in this pathway
BILANGES SERUM RESPONSE TRANSLATION 3720All SZGR 2.0 genes in this pathway
RAO BOUND BY SALL4 ISOFORM B 517302All SZGR 2.0 genes in this pathway
ZWANG CLASS 1 TRANSIENTLY INDUCED BY EGF 516308All SZGR 2.0 genes in this pathway