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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: PEX19

Summary

GeneID

5824

Symbol

PEX19

Synonyms

D1S2223E|HK33|PMP1|PMPI|PXF|PXMP1

Description

peroxisomal biogenesis factor 19

Locus tag

Gene type

protein-coding

Map location

1q23.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.0235

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.00814

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

10704444

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006625

protein targeting to peroxisome

IMP

10704444

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005737

cytoplasm

ISS

GO:0005777

peroxisome

IEA

GO:0005777

peroxisome

ISS

GO:0005778

peroxisomal membrane

IDA

9339377

GO:0016020

membrane

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ABCD1	ABC42 \| ALD \| ALDP \| AMN	ATP-binding cassette, sub-family D (ALD), member 1	ALDP interacts with both farnesylated and mutant farnesyl-deficient PEX19.	BIND	10777694
ABCD1	ABC42 \| ALD \| ALDP \| AMN	ATP-binding cassette, sub-family D (ALD), member 1	-	HPRD,BioGRID	10777694 \|11883941
ABCD2	ABC39 \| ALDL1 \| ALDR \| ALDRP \| hALDR	ATP-binding cassette, sub-family D (ALD), member 2	-	HPRD	10704444 \|10777694
			Reconstituted Complex Two-hybrid	BioGRID	10777694 \|11883941
			ALDRP interacts with both farnesylated and mutant farnesyl-deficient PEX19.	BIND	10777694
ABCD3	ABC43 \| PMP70 \| PXMP1	ATP-binding cassette, sub-family D (ALD), member 3	PMP70 interacts with both farnesylated and mutant farnesyl-deficient PEX19.	BIND	10777694
ABCD3	ABC43 \| PMP70 \| PXMP1	ATP-binding cassette, sub-family D (ALD), member 3	-	HPRD,BioGRID	10777694 \|11453642
PEX10	MGC1998 \| NALD \| RNF69	peroxisomal biogenesis factor 10	PEX10 interacts with PEX19.	BIND	12096124
PEX10	MGC1998 \| NALD \| RNF69	peroxisomal biogenesis factor 10	-	HPRD,BioGRID	10704444
PEX11A	MGC119947 \| MGC138534 \| PEX11-ALPHA	peroxisomal biogenesis factor 11 alpha	-	HPRD	10704444
PEX11B	PEX11-BETA	peroxisomal biogenesis factor 11 beta	PEX11B interacts with PEX19.	BIND	12096124
PEX11B	PEX11-BETA	peroxisomal biogenesis factor 11 beta	-	HPRD,BioGRID	10704444
PEX12	PAF-3	peroxisomal biogenesis factor 12	-	HPRD,BioGRID	10704444
PEX12	PAF-3	peroxisomal biogenesis factor 12	PEX12 interacts with PEX19.	BIND	12096124
PEX13	NALD \| ZWS	peroxisomal biogenesis factor 13	PEX13 interacts with PEX19.	BIND	12096124
PEX13	NALD \| ZWS	peroxisomal biogenesis factor 13	-	HPRD,BioGRID	10704444
PEX14	MGC12767 \| NAPP2 \| Pex14p \| dJ734G22.2	peroxisomal biogenesis factor 14	PEX14 interacts with PEX19.	BIND	12096124
PEX14	MGC12767 \| NAPP2 \| Pex14p \| dJ734G22.2	peroxisomal biogenesis factor 14	-	HPRD,BioGRID	10704444
PEX16	-	peroxisomal biogenesis factor 16	PEX16 interacts with PEX19.	BIND	12096124
PEX16	-	peroxisomal biogenesis factor 16	-	HPRD,BioGRID	10704444 \|11390669
PEX3	DKFZp686N14184 \| FLJ13531 \| TRG18	peroxisomal biogenesis factor 3	-	HPRD,BioGRID	10704444
PEX3	DKFZp686N14184 \| FLJ13531 \| TRG18	peroxisomal biogenesis factor 3	PEX3 interacts with PEX19.	BIND	12096124
PMP22	CMT1A \| CMT1E \| DSS \| GAS-3 \| HMSNIA \| HNPP \| MGC20769 \| Sp110	peripheral myelin protein 22	-	HPRD	10704444
PXMP4	PMP24	peroxisomal membrane protein 4, 24kDa	-	HPRD	10704444
SLC25A17	PMP34	solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17	-	HPRD,BioGRID	10704444

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_PEROXISOME	78	47	All SZGR genes in this pathway
REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	18	11	All SZGR genes in this pathway
REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	34	21	All SZGR genes in this pathway
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES	413	270	All SZGR genes in this pathway
IGARASHI_ATF4_TARGETS_DN	90	65	All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP	579	346	All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN	712	443	All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN	584	395	All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN	848	527	All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN	1024	594	All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP	424	268	All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN	546	351	All SZGR genes in this pathway
AFFAR_YY1_TARGETS_UP	214	133	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN	1237	837	All SZGR genes in this pathway
KAYO_CALORIE_RESTRICTION_MUSCLE_DN	87	59	All SZGR genes in this pathway
BURTON_ADIPOGENESIS_6	189	112	All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED	728	415	All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP	973	570	All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP	863	514	All SZGR genes in this pathway
CHNG_MULTIPLE_MYELOMA_HYPERPLOID_DN	28	19	All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_DN	210	128	All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_ESR1_UP	167	99	All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_DN	253	192	All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP	548	370	All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_NEURAL	129	85	All SZGR genes in this pathway
CHANGOLKAR_H2AFY_TARGETS_DN	40	26	All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN	784	464	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-183	135	142	1A,m8	hsa-miR-183	UAUGGCACUGGUAGAAUUCACUG
miR-205	259	265	1A	hsa-miR-205	UCCUUCAUUCCACCGGAGUCUG
miR-543	310	316	1A	hsa-miR-543	AAACAUUCGCGGUGCACUUCU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.