Gene Page: ZNF462

Summary ?
GeneID58499
SymbolZNF462
SynonymsZfp462
Descriptionzinc finger protein 462
ReferenceHGNC:HGNC:21684|Ensembl:ENSG00000148143|HPRD:10333|Vega:OTTHUMG00000020438
Gene typeprotein-coding
Map location9q31.2
Pascal p-value0.019
Sherlock p-value0.37
eGeneCaudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Putamen basal ganglia
Myers' cis & trans
SupportDarnell FMRP targets
Ascano FMRP targets

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs10184200chr2134561640ZNF462584990.08trans
rs16829545chr2151977407ZNF462584990.04trans
rs16955618chr1529937543ZNF462584997.642E-4trans
rs573327199109720491ZNF462ENSG00000148143.85.233E-70.0195113gtex_brain_putamen_basal
rs120020219109721041ZNF462ENSG00000148143.85.233E-70.0195663gtex_brain_putamen_basal
rs119999639109721364ZNF462ENSG00000148143.85.233E-70.0195986gtex_brain_putamen_basal
rs117904399109724367ZNF462ENSG00000148143.85.233E-70.0198989gtex_brain_putamen_basal
rs105123519109725918ZNF462ENSG00000148143.85.233E-70.01100540gtex_brain_putamen_basal
rs1419721699109727889ZNF462ENSG00000148143.85.233E-70.01102511gtex_brain_putamen_basal
rs117934939109731124ZNF462ENSG00000148143.85.233E-70.01105746gtex_brain_putamen_basal
rs117939589109731533ZNF462ENSG00000148143.85.233E-70.01106155gtex_brain_putamen_basal
rs169260189109731844ZNF462ENSG00000148143.85.233E-70.01106466gtex_brain_putamen_basal
rs101238499109731936ZNF462ENSG00000148143.85.233E-70.01106558gtex_brain_putamen_basal
rs1408268609109733116ZNF462ENSG00000148143.86.197E-70.01107738gtex_brain_putamen_basal
rs1139859349109733120ZNF462ENSG00000148143.85.233E-70.01107742gtex_brain_putamen_basal
rs15102859109733743ZNF462ENSG00000148143.85.233E-70.01108365gtex_brain_putamen_basal
rs557109289109735229ZNF462ENSG00000148143.85.232E-70.01109851gtex_brain_putamen_basal
rs123443179109738406ZNF462ENSG00000148143.85.233E-70.01113028gtex_brain_putamen_basal
rs109786899109740520ZNF462ENSG00000148143.88.168E-70.01115142gtex_brain_putamen_basal
rs109786919109741309ZNF462ENSG00000148143.85.233E-70.01115931gtex_brain_putamen_basal
rs673602449109741801ZNF462ENSG00000148143.85.389E-70.01116423gtex_brain_putamen_basal
rs58997249109741967ZNF462ENSG00000148143.85.149E-70.01116589gtex_brain_putamen_basal
rs9050709109743287ZNF462ENSG00000148143.84.999E-70.01117909gtex_brain_putamen_basal
rs9050719109743427ZNF462ENSG00000148143.84.977E-70.01118049gtex_brain_putamen_basal
rs70491139109745208ZNF462ENSG00000148143.84.774E-70.01119830gtex_brain_putamen_basal
rs680377039109746947ZNF462ENSG00000148143.84.618E-70.01121569gtex_brain_putamen_basal
rs125530319109752583ZNF462ENSG00000148143.84.47E-70.01127205gtex_brain_putamen_basal
rs673930079109755104ZNF462ENSG00000148143.84.423E-70.01129726gtex_brain_putamen_basal
rs727437129109755320ZNF462ENSG00000148143.84.404E-70.01129942gtex_brain_putamen_basal
rs70431079109755972ZNF462ENSG00000148143.84.357E-70.01130594gtex_brain_putamen_basal
rs109786979109763587ZNF462ENSG00000148143.81.225E-60.01138209gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
CDK90.830.81
THOC50.820.81
INTS30.810.81
WDR590.800.81
DDX270.800.80
SUPT7L0.800.79
C1orf1740.800.82
COG70.800.79
MSTO10.800.81
IQCC0.800.80
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AF347015.31-0.70-0.66
MT-CO2-0.70-0.65
AF347015.21-0.69-0.68
AF347015.8-0.68-0.65
MT-CYB-0.68-0.63
AF347015.27-0.67-0.64
AF347015.2-0.66-0.62
AF347015.33-0.65-0.61
AF347015.15-0.64-0.63
HIGD1B-0.62-0.62

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
TURASHVILI BREAST DUCTAL CARCINOMA VS DUCTAL NORMAL DN 198110All SZGR 2.0 genes in this pathway
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE DN 6135All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 1 UP 12171All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 6HR DN 514330All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT AND CANCER BOX4 DN 3222All SZGR 2.0 genes in this pathway
MOLENAAR TARGETS OF CCND1 AND CDK4 UP 6748All SZGR 2.0 genes in this pathway
ACEVEDO METHYLATED IN LIVER CANCER DN 940425All SZGR 2.0 genes in this pathway
KOINUMA TARGETS OF SMAD2 OR SMAD3 824528All SZGR 2.0 genes in this pathway
ZHOU CELL CYCLE GENES IN IR RESPONSE 2HR 85All SZGR 2.0 genes in this pathway