Gene Page: SCAF1
Summary ?
| GeneID | 58506 |
| Symbol | SCAF1 |
| Synonyms | SRA1 |
| Description | SR-related CTD associated factor 1 |
| Reference | HGNC:HGNC:30403|Ensembl:ENSG00000126461|HPRD:11604|Vega:OTTHUMG00000183238 |
| Gene type | protein-coding |
| Map location | 19q13.3-q13.4 |
| Pascal p-value | 4.712E-7 |
| Sherlock p-value | 0.552 |
| Fetal beta | -0.491 |
| Support | CompositeSet Darnell FMRP targets Ascano FMRP targets |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| KIF15 | 0.91 | 0.52 |
| MCM10 | 0.91 | 0.44 |
| PRC1 | 0.91 | 0.57 |
| KIF23 | 0.90 | 0.51 |
| TOP2A | 0.90 | 0.44 |
| KIF4A | 0.90 | 0.48 |
| CDK2 | 0.90 | 0.43 |
| NCAPH | 0.90 | 0.53 |
| BRIP1 | 0.90 | 0.51 |
| CEP55 | 0.90 | 0.46 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.31 | -0.34 | -0.44 |
| AF347015.27 | -0.34 | -0.44 |
| MT-CO2 | -0.33 | -0.44 |
| MT-CYB | -0.33 | -0.42 |
| PTH1R | -0.32 | -0.33 |
| AF347015.33 | -0.32 | -0.40 |
| SLC9A3R2 | -0.32 | -0.24 |
| AIFM3 | -0.32 | -0.35 |
| C5orf53 | -0.32 | -0.32 |
| AF347015.15 | -0.32 | -0.42 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| GINESTIER BREAST CANCER ZNF217 AMPLIFIED DN | 335 | 193 | All SZGR 2.0 genes in this pathway |
| BENPORATH NANOG TARGETS | 988 | 594 | All SZGR 2.0 genes in this pathway |
| BENPORATH SOX2 TARGETS | 734 | 436 | All SZGR 2.0 genes in this pathway |
| WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 8D | 882 | 506 | All SZGR 2.0 genes in this pathway |
| WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND WITH H4K20ME1 MARK | 145 | 82 | All SZGR 2.0 genes in this pathway |
| DELACROIX RARG BOUND MEF | 367 | 231 | All SZGR 2.0 genes in this pathway |