Gene Page: RARG

Summary
GeneID  5916
Symbol  RARG
Synonyms  NR1B3|RARC
Description  retinoic acid receptor, gamma
See related  HGNC:9866|MIM:180190|Ensembl:ENSG00000172819|HPRD:01573|
Locus tag  -
Gene type  protein-coding
Map location  12q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PDE6C0.500.29
TAS2R40.500.41
CILP0.500.44
TAS2R480.500.43
NAT80.490.39
TGM10.480.41
PLA2G4B0.480.39
MST1R0.480.42
AC034236.30.470.36
SLC4A50.470.45
Top 10 negatively co-expressed genes
IFI27-0.28-0.37
RRAS-0.28-0.37
ITM2A-0.28-0.35
GNG11-0.27-0.38
ABCG2-0.27-0.36
RP11-884K10.1-0.27-0.36
TM4SF18-0.27-0.33
MT-CO2-0.26-0.34
C1orf64-0.26-0.28
S100A4-0.26-0.35
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityIEA-
GO:0003707steroid hormone receptor activityIEA-
GO:0003708retinoic acid receptor activityTAS2157970 
GO:0005515protein bindingIPI10428834 
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingIEA-
GO:0046965retinoid X receptor bindingISS-
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000122negative regulation of transcription from RNA polymerase II promoterISS-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
GO:0008285negative regulation of cell proliferationISS-
GO:0008361regulation of cell sizeTAS18438858 
GO:0048048embryonic eye morphogenesisIEA-
GO:0007275multicellular organismal developmentTAS2157970 
GO:0043065positive regulation of apoptosisIEA-
GO:0048384retinoic acid receptor signaling pathwayIDA17943189 
GO:0032526response to retinoic acidIDA17943189 
GO:0035116embryonic hindlimb morphogenesisISS-
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA-
GO:0060070Wnt receptor signaling pathway through beta-cateninTAS18484682 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005667transcription factor complexIEA-
GO:0016021integral to membraneNAS17943189 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DMPKDM | DM1 | DM1PK | DMK | MDPK | MT-PKdystrophia myotonica-protein kinaseMutant DMPK mRNA interacts with RAR-gamma.BIND14657503 
NCOR1KIAA1047 | MGC104216 | N-CoR | TRAC1 | hCIT529I10 | hN-CoRnuclear receptor co-repressor 1Reconstituted Complex
Two-hybrid		BioGRID10336495 
NR2F6EAR-2 | EAR2 | ERBAL2nuclear receptor subfamily 2, group F, member 6Two-hybridBioGRID10318855 
RXRAFLJ00280 | FLJ00318 | FLJ16020 | FLJ16733 | MGC102720 | NR2B1retinoid X receptor, alpha-HPRD10835357 
SRFMCM1serum response factor (c-fos serum response element-binding transcription factor)Reconstituted ComplexBioGRID11641790 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_RXR_VDR_PATHWAY 2624All SZGR genes in this pathway
PID_RETINOIC_ACID_PATHWAY 3023All SZGR genes in this pathway
REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 352181All SZGR genes in this pathway
REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY 4936All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_DN 3722All SZGR genes in this pathway
ZIRN_TRETINOIN_RESPONSE_UP 2113All SZGR genes in this pathway
AMUNDSON_GENOTOXIC_SIGNATURE 10568All SZGR genes in this pathway
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN 5142All SZGR genes in this pathway
KIM_MYCN_AMPLIFICATION_TARGETS_UP 9264All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 229137All SZGR genes in this pathway
SHIN_B_CELL_LYMPHOMA_CLUSTER_7 2722All SZGR genes in this pathway
HOFMANN_CELL_LYMPHOMA_DN 3929All SZGR genes in this pathway
MURAKAMI_UV_RESPONSE_6HR_DN 2113All SZGR genes in this pathway
SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_DN 1814All SZGR genes in this pathway
MURAKAMI_UV_RESPONSE_24HR 2013All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_UP 673430All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN 593372All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN 591366All SZGR genes in this pathway
MCCABE_BOUND_BY_HOXC6 469239All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING 510309All SZGR genes in this pathway
MATTHEWS_SKIN_CARCINOGENESIS_VIA_JUN 1710All SZGR genes in this pathway
PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION 3021All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN 238145All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP 395249All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN 442275All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED 536296All SZGR genes in this pathway
YAMASHITA_LIVER_CANCER_STEM_CELL_UP 4738All SZGR genes in this pathway
YAMASHITA_LIVER_CANCER_STEM_CELL_DN 7651All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_DN 8251All SZGR genes in this pathway
WANG_NFKB_TARGETS 2515All SZGR genes in this pathway
DELACROIX_RARG_BOUND_MEF 367231All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_DN 211119All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124/506657663m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-142-3p7117181A,m8hsa-miR-142-3pUGUAGUGUUUCCUACUUUAUGGA
miR-1821321391A,m8hsa-miR-182UUUGGCAAUGGUAGAACUCACA
hsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-24410416m8hsa-miR-24SZUGGCUCAGUUCAGCAGGAACAG
miR-30-5p102810351A,m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-326822828m8hsa-miR-326CCUCUGGGCCCUUCCUCCAG
miR-331884890m8hsa-miR-331brainGCCCCUGGGCCUAUCCUAGAA
miR-34/449273279m8hsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
miR-961331391Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
hsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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