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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: RELA

Summary

GeneID

5970

Symbol

RELA

Synonyms

MGC131774|NFKB3|p65

Description

v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Locus tag

Gene type

protein-coding

Map location

11q13

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0873

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

MEN1

0.90

0.91

EDC4

0.89

0.92

SETD1A

0.89

0.90

BAT2

0.89

0.91

RAI1

0.89

0.90

ZNF777

0.89

0.91

STRN4

0.89

0.90

CNOT3

0.88

0.89

PHRF1

0.88

0.90

AKAP8

0.88

0.89

Top 10 negatively co-expressed genes

AF347015.31

-0.79

-0.83

MT-CO2

-0.79

-0.83

AF347015.27

-0.77

-0.82

AF347015.33

-0.77

-0.80

MT-CYB

-0.76

-0.81

AF347015.8

-0.76

-0.82

AF347015.21

-0.75

-0.87

S100B

-0.74

-0.80

AF347015.15

-0.73

-0.79

COPZ2

-0.71

-0.76

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003700

transcription factor activity

IEA

GO:0003705

RNA polymerase II transcription factor activity, enhancer binding

IDA

3091258

GO:0042301

phosphate binding

IDA

10521409

GO:0051059

NF-kappaB binding

IPI

8441377

GO:0042802

identical protein binding

IDA

9437432

GO:0019901

protein kinase binding

IPI

10521409 |15465828

GO:0047485

protein N-terminus binding

IPI

7739562

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0010033

response to organic substance

IDA

10747850

GO:0006968

cellular defense response

NAS

8717528

GO:0010224

response to UV-B

IDA

15616591

GO:0006954

inflammatory response

IDA

12924514

GO:0006916

anti-apoptosis

IDA

10747850

GO:0051092

positive regulation of NF-kappaB transcription factor activity

IDA

15790681

GO:0051607

defense response to virus

NAS

8717528

GO:0019221

cytokine-mediated signaling pathway

IDA

15876188

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

IEP

12761501

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005829

cytosol

EXP

10723127

GO:0005634

nucleus

IDA

3140380

GO:0005634

nucleus

IEA

GO:0005654

nucleoplasm

EXP

10723127

GO:0005667

transcription factor complex

IDA

12048232

GO:0005737

cytoplasm

IDA

3140380

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AES	AES-1 \| AES-2 \| ESP1 \| GRG \| GRG5 \| TLE5	amino-terminal enhancer of split	AES interacts with p65.	BIND	10660609
AES	AES-1 \| AES-2 \| ESP1 \| GRG \| GRG5 \| TLE5	amino-terminal enhancer of split	-	HPRD,BioGRID	10660609
AHR	-	aryl hydrocarbon receptor	-	HPRD,BioGRID	11114727 \|12181450
AIFM1	AIF \| MGC111425 \| PDCD8	apoptosis-inducing factor, mitochondrion-associated, 1	-	HPRD	14743216
AKAP8L	DKFZp434L0650 \| HA95 \| HAP95 \| NAKAP \| NAKAP95	A kinase (PRKA) anchor protein 8-like	-	HPRD,BioGRID	14743216
APBA2	D15S1518E \| HsT16821 \| LIN-10 \| MGC99508 \| MGC:14091 \| MINT2 \| X11L	amyloid beta (A4) precursor protein-binding, family A, member 2	-	HPRD,BioGRID	10777610
AR	AIS \| DHTR \| HUMARA \| KD \| NR3C4 \| SBMA \| SMAX1 \| TFM	androgen receptor	-	HPRD	8798655
ASCC1	ASC1p50 \| CGI-18 \| RP11-150D20.4	activating signal cointegrator 1 complex subunit 1	Reconstituted Complex Two-hybrid	BioGRID	12077347
ASCC2	ASC1p100	activating signal cointegrator 1 complex subunit 2	Reconstituted Complex Two-hybrid	BioGRID	12077347
ASCC3	ASC1p200 \| DJ467N11.1 \| HELIC1 \| MGC26074 \| RNAH \| dJ121G13.4	activating signal cointegrator 1 complex subunit 3	Reconstituted Complex Two-hybrid	BioGRID	12077347
ATP5A1	ATP5A \| ATP5AL2 \| ATPM \| MOM2 \| OMR \| ORM \| hATP1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	-	HPRD	14743216
BARD1	-	BRCA1 associated RING domain 1	Affinity Capture-Western	BioGRID	12700228
BIRC3	AIP1 \| API2 \| CIAP2 \| HAIP1 \| HIAP1 \| MALT2 \| MIHC \| RNF49	baculoviral IAP repeat-containing 3	The cIAP-2 promoter interacts with p65.	BIND	15494311
BRCA1	BRCAI \| BRCC1 \| IRIS \| PSCP \| RNF53	breast cancer 1, early onset	-	HPRD,BioGRID	12700228
BTRC	BETA-TRCP \| FBW1A \| FBXW1 \| FBXW1A \| FWD1 \| MGC4643 \| bTrCP \| bTrCP1 \| betaTrCP	beta-transducin repeat containing	-	HPRD,BioGRID	9990853
CARM1	PRMT4	coactivator-associated arginine methyltransferase 1	CARM1 interacts with p65.	BIND	15616592
CCND1	BCL1 \| D11S287E \| PRAD1 \| U21B31	cyclin D1	RELA (NF-kappaB p65 subunit) interacts with the CCND1 (Cyclin D1) promoter.	BIND	15652748
CCT8	C21orf112 \| Cctq \| D21S246 \| KIAA0002 \| PRED71	chaperonin containing TCP1, subunit 8 (theta)	-	HPRD	14743216
CDK9	C-2k \| CDC2L4 \| CTK1 \| PITALRE \| TAK	cyclin-dependent kinase 9	-	HPRD,BioGRID	12173051
CEBPB	C/EBP-beta \| CRP2 \| IL6DBP \| LAP \| MGC32080 \| NF-IL6 \| TCF5	CCAAT/enhancer binding protein (C/EBP), beta	-	HPRD,BioGRID	9570146 \|12707271
CEBPD	C/EBP-delta \| CELF \| CRP3 \| NF-IL6-beta	CCAAT/enhancer binding protein (C/EBP), delta	-	HPRD,BioGRID	9570146
CHEK1	CHK1	CHK1 checkpoint homolog (S. pombe)	RELA interacts with CHEK1. This interaction was modeled on a demonstrated interaction between human RELA, and CHEK1 from an unspecified species.	BIND	15775976
CHUK	IKBKA \| IKK-alpha \| IKK1 \| IKKA \| NFKBIKA \| TCF16	conserved helix-loop-helix ubiquitous kinase	RELA (p65) interacts with CHUK (I-kappa-B-alpha).	BIND	15845455
CHUK	IKBKA \| IKK-alpha \| IKK1 \| IKKA \| NFKBIKA \| TCF16	conserved helix-loop-helix ubiquitous kinase	I-kappa-B-alpha interacts with RelA.	BIND	15994554
CREBBP	CBP \| KAT3A \| RSTS	CREB binding protein	-	HPRD,BioGRID	9548485
			CBP interacts with p65.	BIND	9096323
			RELA (NF-kappaB p65) interacts with CREBBP (CBP).	BIND	16007092
CSNK2A1	CK2A1 \| CKII	casein kinase 2, alpha 1 polypeptide	-	HPRD,BioGRID	10938077
CSNK2A2	CK2A2 \| CSNK2A1 \| FLJ43934	casein kinase 2, alpha prime polypeptide	Affinity Capture-Western Biochemical Activity	BioGRID	10938077
CXCL10	C7 \| IFI10 \| INP10 \| IP-10 \| SCYB10 \| crg-2 \| gIP-10 \| mob-1	chemokine (C-X-C motif) ligand 10	p65 interacts with promoter IP-10.	BIND	15315758
DHX9	DDX9 \| LKP \| NDHII \| RHA	DEAH (Asp-Glu-Ala-His) box polypeptide 9	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	15355351
DHX9	DDX9 \| LKP \| NDHII \| RHA	DEAH (Asp-Glu-Ala-His) box polypeptide 9	-	HPRD	14743216
EGR1	AT225 \| G0S30 \| KROX-24 \| NGFI-A \| TIS8 \| ZIF-268 \| ZNF225	early growth response 1	-	HPRD,BioGRID	10671503
EGR1	AT225 \| G0S30 \| KROX-24 \| NGFI-A \| TIS8 \| ZIF-268 \| ZNF225	early growth response 1	RelA interacts with Egr-1 promoter.	BIND	15616591
EP300	KAT3B \| p300	E1A binding protein p300	p300 interacts with p65.	BIND	9096323
			p300 interacts with p65.	BIND	15616592
			-	HPRD,BioGRID	9096323
ETHE1	HSCO \| YF13H12	ethylmalonic encephalopathy 1	-	HPRD,BioGRID	12398897
FOS	AP-1 \| C-FOS	v-fos FBJ murine osteosarcoma viral oncogene homolog	NF-kappa-B interacts with c-Fos.	BIND	10488148
FOS	AP-1 \| C-FOS	v-fos FBJ murine osteosarcoma viral oncogene homolog	Phenotypic Enhancement Two-hybrid	BioGRID	10488148
FUS	CHOP \| FUS-CHOP \| FUS1 \| TLS \| TLS/CHOP \| hnRNP-P2	fusion (involved in t(12;16) in malignant liposarcoma)	-	HPRD,BioGRID	11278855
GCN1L1	GCN1 \| GCN1L \| KIAA0219	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	-	HPRD	14743216
GTF2B	TF2B \| TFIIB	general transcription factor IIB	Reconstituted Complex	BioGRID	7706261
HAX1	FLJ17042 \| FLJ18492 \| FLJ93803 \| HCLSBP1 \| HS1BP1 \| SCN3	HCLS1 associated protein X-1	-	HPRD	14743216
HDAC1	DKFZp686H12203 \| GON-10 \| HD1 \| RPD3 \| RPD3L1	histone deacetylase 1	-	HPRD,BioGRID	11564889
HDAC2	RPD3 \| YAF1	histone deacetylase 2	-	HPRD,BioGRID	12138131 \|12419806
HDAC3	HD3 \| RPD3 \| RPD3-2	histone deacetylase 3	Affinity Capture-Western	BioGRID	11533489
HEXIM1	CLP1 \| EDG1 \| FLJ13562 \| HIS1 \| MAQ1	hexamethylene bis-acetamide inducible 1	-	HPRD,BioGRID	12581153
HMGA2	BABL \| HMGI-C \| HMGIC \| LIPO \| STQTL9	high mobility group AT-hook 2	Reconstituted Complex	BioGRID	12693954
HMGB1	DKFZp686A04236 \| HMG1 \| HMG3 \| SBP-1	high-mobility group box 1	-	HPRD,BioGRID	12665595
HSPA8	HSC54 \| HSC70 \| HSC71 \| HSP71 \| HSP73 \| HSPA10 \| LAP1 \| MGC131511 \| MGC29929 \| NIP71	heat shock 70kDa protein 8	-	HPRD	14743216
IL8	CXCL8 \| GCP-1 \| GCP1 \| LECT \| LUCT \| LYNAP \| MDNCF \| MONAP \| NAF \| NAP-1 \| NAP1	interleukin 8	The IL-8 promoter interacts with p65.	BIND	15494311
ING4	MGC12557 \| my036 \| p29ING4	inhibitor of growth family, member 4	-	HPRD,BioGRID	15029197
ING4	MGC12557 \| my036 \| p29ING4	inhibitor of growth family, member 4	ING4 interacts with p65.	BIND	15029197
IQGAP2	-	IQ motif containing GTPase activating protein 2	Affinity Capture-MS	BioGRID	14743216
IRAK1BP1	AIP70 \| MGC138458 \| MGC138460 \| SIMPL	interleukin-1 receptor-associated kinase 1 binding protein 1	-	HPRD	15485901
IRF2	DKFZp686F0244 \| IRF-2	interferon regulatory factor 2	-	HPRD,BioGRID	8550813
ITGB3BP	CENP-R \| CENPR \| HSU37139 \| NRIF3 \| TAP20	integrin beta 3 binding protein (beta3-endonexin)	-	HPRD,BioGRID	12244126
JUN	AP-1 \| AP1 \| c-Jun	jun oncogene	NF-kappa-B interacts with c-Jun.	BIND	10488148
JUN	AP-1 \| AP1 \| c-Jun	jun oncogene	-	HPRD,BioGRID	9468519 \|10488148
KPNA2	IPOA1 \| QIP2 \| RCH1 \| SRP1alpha	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	-	HPRD,BioGRID	12504098
MAP3K8	COT \| EST \| ESTF \| FLJ10486 \| TPL2 \| Tpl-2 \| c-COT	mitogen-activated protein kinase kinase kinase 8	Affinity Capture-MS	BioGRID	14743216
MEN1	MEAI \| SCG2	multiple endocrine neoplasia I	-	HPRD,BioGRID	11526476
MTPN	FLJ31098 \| FLJ99857 \| GCDP \| V-1	myotrophin	Affinity Capture-Western Reconstituted Complex	BioGRID	11971907
MYC	bHLHe39 \| c-Myc	v-myc myelocytomatosis viral oncogene homolog (avian)	-	HPRD,BioGRID	12027803
NCF1	FLJ79451 \| NCF1A \| NOXO2 \| SH3PXD1A \| p47phox	neutrophil cytosolic factor 1	Affinity Capture-Western Reconstituted Complex	BioGRID	12618429
NCOA3	ACTR \| AIB-1 \| AIB1 \| CAGH16 \| CTG26 \| KAT13B \| MGC141848 \| RAC3 \| SRC3 \| TNRC14 \| TNRC16 \| TRAM-1 \| pCIP	nuclear receptor coactivator 3	SRC-3 interacts with NF-kappa-B.	BIND	15383283
NCOA6	AIB3 \| ANTP \| ASC2 \| HOX1.1 \| HOXA7 \| KIAA0181 \| NRC \| PRIP \| RAP250 \| TRBP	nuclear receptor coactivator 6	Reconstituted Complex	BioGRID	10847592
NCOR2	CTG26 \| SMRT \| SMRTE \| SMRTE-tau \| TNRC14 \| TRAC-1 \| TRAC1	nuclear receptor co-repressor 2	-	HPRD,BioGRID	12589049
NFKB1	DKFZp686C01211 \| EBP-1 \| KBF1 \| MGC54151 \| NF-kappa-B \| NFKB-p105 \| NFKB-p50 \| p105	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	Affinity Capture-MS Reconstituted Complex	BioGRID	8798655 \|14743216
			NFKB1 (p50) interacts with RELA (p65).	BIND	15735750
			p50 interacts with p65. This interaction was modeled on a demonstrated interaction between mouse p50 and mouse p65.	BIND	9738011
			-	HPRD	8649779
NFKB2	LYT-10 \| LYT10	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	-	HPRD,BioGRID	8413211
NFKBIA	IKBA \| MAD-3 \| NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	Affinity Capture-Western Reconstituted Complex	BioGRID	8139561 \|9738011 \|9751059 \|9990853 \|11313474 \|11533489 \|12419806
			I-kappa-B-alpha interacts with NF-kappa-B-p65.	BIND	15125834
			RelA, the p65 subunit of the NF-kappaB complex, interacts with I-kappaB-alpha	BIND	14685242
NFKBIB	IKBB \| TRIP9	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	-	HPRD,BioGRID	8816457 \|12672800
			RelA, the p65 subunit of the NF-kappaB complex, interacts with I-kappaB-beta	BIND	14685242
			I-kappa-B-beta interacts with p65. This interaction was modeled on a demonstrated interaction between mouse I-kappa-B-beta and mouse p65.	BIND	8816457
NFKBIE	IKBE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	9315679
NKRF	ITBA4 \| NRF	NFKB repressing factor	Reconstituted Complex	BioGRID	10562553
NKX2-1	BCH \| BHC \| NK-2 \| NKX2.1 \| NKX2A \| TEBP \| TITF1 \| TTF-1 \| TTF1	NK2 homeobox 1	Affinity Capture-Western	BioGRID	12040027
NOTCH1	TAN1 \| hN1	Notch homolog 1, translocation-associated (Drosophila)	-	HPRD,BioGRID	8642313
NPM1	B23 \| MGC104254 \| NPM	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	-	HPRD	14743216
NR3C1	GCCR \| GCR \| GR \| GRL	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	Affinity Capture-Western in vitro in vivo	BioGRID	7659084 \|8290595 \|10995388
NR3C1	GCCR \| GCR \| GR \| GRL		-	HPRD	7659084 \|10995388
PAPOLA	MGC5378 \| PAP	poly(A) polymerase alpha	-	HPRD	14743216
PARP1	ADPRT \| ADPRT1 \| PARP \| PARP-1 \| PPOL \| pADPRT-1	poly (ADP-ribose) polymerase 1	-	HPRD,BioGRID	11590148
PGR	NR3C3 \| PR	progesterone receptor	-	HPRD,BioGRID	8626413
PHB2	BAP \| BCAP37 \| Bap37 \| MGC117268 \| PNAS-141 \| REA \| p22	prohibitin 2	-	HPRD	14743216
PIAS1	DDXBP1 \| GBP \| GU/RH-II \| MGC141878 \| MGC141879 \| ZMIZ3	protein inhibitor of activated STAT, 1	-	HPRD	15657437
PIAS3	FLJ14651 \| ZMIZ5	protein inhibitor of activated STAT, 3	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	15140884
PML	MYL \| PP8675 \| RNF71 \| TRIM19	promyelocytic leukemia	-	HPRD,BioGRID	12540841
POU2F1	OCT1 \| OTF1	POU class 2 homeobox 1	-	HPRD,BioGRID	12019209
PPARA	MGC2237 \| MGC2452 \| NR1C1 \| PPAR \| hPPAR	peroxisome proliferator-activated receptor alpha	-	HPRD,BioGRID	10542237
PPP1R13L	IASPP \| NKIP1 \| RAI	protein phosphatase 1, regulatory (inhibitor) subunit 13 like	-	HPRD,BioGRID	10336463
PPP2CA	PP2Ac \| PP2CA \| RP-C	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	Reconstituted Complex	BioGRID	11591705
PPP2CB	PP2CB	protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform	Reconstituted Complex	BioGRID	11591705
PPP4C	PP4 \| PPH3 \| PPX	protein phosphatase 4 (formerly X), catalytic subunit	-	HPRD,BioGRID	9837938
PRKCZ	PKC-ZETA \| PKC2	protein kinase C, zeta	-	HPRD,BioGRID	11684013
REL	C-Rel	v-rel reticuloendotheliosis viral oncogene homolog (avian)	-	HPRD	7886940 \|11967310
REL	C-Rel	v-rel reticuloendotheliosis viral oncogene homolog (avian)	Affinity Capture-MS Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	8139561 \|11967310 \|14743216
RELA	MGC131774 \| NFKB3 \| p65	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Two-hybrid	BioGRID	10336463
RELB	I-REL \| IREL	v-rel reticuloendotheliosis viral oncogene homolog B	Affinity Capture-MS	BioGRID	14743216
RFC1	A1 \| MGC51786 \| MHCBFB \| PO-GA \| RECC1 \| RFC \| RFC140	replication factor C (activator 1) 1, 145kDa	-	HPRD,BioGRID	12509469
RNF25	AO7 \| FLJ13906	ring finger protein 25	-	HPRD,BioGRID	12748188
RPL18	-	ribosomal protein L18	-	HPRD	14743216
RPS3	FLJ26283 \| FLJ27450 \| MGC87870	ribosomal protein S3	-	HPRD	14743216
RUVBL2	CGI-46 \| ECP51 \| INO80J \| REPTIN \| RVB2 \| TIH2 \| TIP48 \| TIP49B	RuvB-like 2 (E. coli)	-	HPRD	14743216
RXRA	FLJ00280 \| FLJ00318 \| FLJ16020 \| FLJ16733 \| MGC102720 \| NR2B1	retinoid X receptor, alpha	Reconstituted Complex	BioGRID	10075655
SLC1A2	EAAT2 \| GLT-1	solute carrier family 1 (glial high affinity glutamate transporter), member 2	p65 interacts with the EAAT2 promoter.	BIND	15660126
SP1	-	Sp1 transcription factor	-	HPRD	7933095\|12055073
SP1	-	Sp1 transcription factor	Affinity Capture-Western Reconstituted Complex	BioGRID	7933095 \|12055073
SRF	MCM1	serum response factor (c-fos serum response element-binding transcription factor)	Reconstituted Complex	BioGRID	8670842
STAT3	APRF \| FLJ20882 \| HIES \| MGC16063	signal transducer and activator of transcription 3 (acute-phase response factor)	-	HPRD,BioGRID	12057007
TAF1	BA2R \| CCG1 \| CCGS \| DYT3 \| KAT4 \| N-TAF1 \| NSCL2 \| OF \| P250 \| TAF2A \| TAFII250	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	-	HPRD,BioGRID	9584164
TAF11	MGC:15243 \| PRO2134 \| TAF2I \| TAFII28	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa	-	HPRD,BioGRID	9584164
TAF4B	TAF2C2 \| TAFII105	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa	Reconstituted Complex	BioGRID	9724652
TAF6	DKFZp781E21155 \| MGC:8964 \| TAF2E \| TAFII70 \| TAFII80 \| TAFII85	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa	-	HPRD,BioGRID	9584164
TBK1	FLJ11330 \| NAK \| T2K	TANK-binding kinase 1	Affinity Capture-MS	BioGRID	14743216
TBP	GTF2D \| GTF2D1 \| MGC117320 \| MGC126054 \| MGC126055 \| SCA17 \| TFIID	TATA box binding protein	-	HPRD,BioGRID	7706261 \|9584164
TERT	EST2 \| TCS1 \| TP2 \| TRT \| hEST2	telomerase reverse transcriptase	An unspecified isoform of TERT (hTERT) interacts with RELA (p65).	BIND	12917431
TERT	EST2 \| TCS1 \| TP2 \| TRT \| hEST2	telomerase reverse transcriptase	-	HPRD,BioGRID	12517770
TLE1	ESG \| ESG1 \| GRG1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	TLE1 interacts with p65.	BIND	10660609
TLE1	ESG \| ESG1 \| GRG1		Affinity Capture-Western	BioGRID	10660609
TNIP2	ABIN-2 \| ABIN2 \| FLIP1 \| KLIP \| MGC4289	TNFAIP3 interacting protein 2	-	HPRD,BioGRID	14743216
TP53BP2	53BP2 \| ASPP2 \| BBP \| PPP1R13A \| p53BP2	tumor protein p53 binding protein, 2	-	HPRD	10498867
TRIB3	C20orf97 \| NIPK \| SINK \| SKIP3 \| TRB3	tribbles homolog 3 (Drosophila)	Affinity Capture-Western	BioGRID	12736262
TRIP4	HsT17391	thyroid hormone receptor interactor 4	-	HPRD	12077347
TSC22D3	DIP \| DKFZp313A1123 \| DSIPI \| GILZ \| TSC-22R \| hDIP	TSC22 domain family, member 3	-	HPRD	12393603
TUBA3C	TUBA2 \| bA408E5.3	tubulin, alpha 3c	-	HPRD	14743216
TUBB2B	DKFZp566F223 \| FLJ98847 \| MGC8685 \| TUBB-PARALOG \| bA506K6.1	tubulin, beta 2B	-	HPRD	14743216
TWIST1	ACS3 \| BPES2 \| BPES3 \| SCS \| TWIST \| bHLHa38	twist homolog 1 (Drosophila)	-	HPRD,BioGRID	12553906
UNC5CL	MGC34763 \| ZUD	unc-5 homolog C (C. elegans)-like	-	HPRD,BioGRID	14769797

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_MAPK_SIGNALING_PATHWAY	267	205	All SZGR genes in this pathway
KEGG_CHEMOKINE_SIGNALING_PATHWAY	190	128	All SZGR genes in this pathway
KEGG_APOPTOSIS	88	62	All SZGR genes in this pathway
KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	102	88	All SZGR genes in this pathway
KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY	62	47	All SZGR genes in this pathway
KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY	71	51	All SZGR genes in this pathway
KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY	56	44	All SZGR genes in this pathway
KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY	108	89	All SZGR genes in this pathway
KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY	75	56	All SZGR genes in this pathway
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY	126	103	All SZGR genes in this pathway
KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY	67	57	All SZGR genes in this pathway
KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION	68	44	All SZGR genes in this pathway
KEGG_LEISHMANIA_INFECTION	72	56	All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER	328	259	All SZGR genes in this pathway
KEGG_PANCREATIC_CANCER	70	56	All SZGR genes in this pathway
KEGG_PROSTATE_CANCER	89	75	All SZGR genes in this pathway
KEGG_CHRONIC_MYELOID_LEUKEMIA	73	59	All SZGR genes in this pathway
KEGG_ACUTE_MYELOID_LEUKEMIA	60	47	All SZGR genes in this pathway
KEGG_SMALL_CELL_LUNG_CANCER	84	67	All SZGR genes in this pathway
BIOCARTA_RELA_PATHWAY	16	12	All SZGR genes in this pathway
BIOCARTA_AKT_PATHWAY	22	16	All SZGR genes in this pathway
BIOCARTA_ATM_PATHWAY	20	16	All SZGR genes in this pathway
BIOCARTA_RANKL_PATHWAY	14	13	All SZGR genes in this pathway
BIOCARTA_CDMAC_PATHWAY	16	15	All SZGR genes in this pathway
BIOCARTA_CD40_PATHWAY	15	13	All SZGR genes in this pathway
BIOCARTA_CERAMIDE_PATHWAY	22	16	All SZGR genes in this pathway
BIOCARTA_TID_PATHWAY	19	15	All SZGR genes in this pathway
BIOCARTA_GCR_PATHWAY	22	17	All SZGR genes in this pathway
BIOCARTA_CXCR4_PATHWAY	24	22	All SZGR genes in this pathway
BIOCARTA_RNA_PATHWAY	10	9	All SZGR genes in this pathway
BIOCARTA_EPONFKB_PATHWAY	11	11	All SZGR genes in this pathway
BIOCARTA_FMLP_PATHWAY	39	29	All SZGR genes in this pathway
BIOCARTA_FREE_PATHWAY	10	7	All SZGR genes in this pathway
BIOCARTA_HIVNEF_PATHWAY	58	43	All SZGR genes in this pathway
BIOCARTA_HCMV_PATHWAY	17	16	All SZGR genes in this pathway
BIOCARTA_GSK3_PATHWAY	27	26	All SZGR genes in this pathway
BIOCARTA_DEATH_PATHWAY	33	24	All SZGR genes in this pathway
BIOCARTA_RACCYCD_PATHWAY	26	23	All SZGR genes in this pathway
BIOCARTA_KERATINOCYTE_PATHWAY	46	38	All SZGR genes in this pathway
BIOCARTA_MAPK_PATHWAY	87	68	All SZGR genes in this pathway
BIOCARTA_PPARA_PATHWAY	58	43	All SZGR genes in this pathway
BIOCARTA_VIP_PATHWAY	29	26	All SZGR genes in this pathway
BIOCARTA_NTHI_PATHWAY	24	20	All SZGR genes in this pathway
BIOCARTA_NFKB_PATHWAY	23	19	All SZGR genes in this pathway
BIOCARTA_RAS_PATHWAY	23	20	All SZGR genes in this pathway
BIOCARTA_CARDIACEGF_PATHWAY	18	16	All SZGR genes in this pathway
BIOCARTA_IL1R_PATHWAY	33	29	All SZGR genes in this pathway
BIOCARTA_TCR_PATHWAY	49	37	All SZGR genes in this pathway
BIOCARTA_TALL1_PATHWAY	15	15	All SZGR genes in this pathway
BIOCARTA_41BB_PATHWAY	17	15	All SZGR genes in this pathway
BIOCARTA_STRESS_PATHWAY	25	18	All SZGR genes in this pathway
BIOCARTA_TNFR2_PATHWAY	18	15	All SZGR genes in this pathway
BIOCARTA_TOLL_PATHWAY	37	31	All SZGR genes in this pathway
PID_FCER1_PATHWAY	62	43	All SZGR genes in this pathway
PID_BCR_5PATHWAY	65	50	All SZGR genes in this pathway
PID_LYSOPHOSPHOLIPID_PATHWAY	66	53	All SZGR genes in this pathway
PID_P73PATHWAY	79	59	All SZGR genes in this pathway
PID_NFKAPPAB_ATYPICAL_PATHWAY	17	15	All SZGR genes in this pathway
PID_NFKAPPAB_CANONICAL_PATHWAY	23	20	All SZGR genes in this pathway
PID_CD40_PATHWAY	31	26	All SZGR genes in this pathway
PID_IL12_2PATHWAY	63	54	All SZGR genes in this pathway
PID_AVB3_OPN_PATHWAY	31	29	All SZGR genes in this pathway
PID_ANGIOPOIETIN_RECEPTOR_PATHWAY	50	41	All SZGR genes in this pathway
PID_HDAC_CLASSI_PATHWAY	66	50	All SZGR genes in this pathway
PID_IL1_PATHWAY	34	28	All SZGR genes in this pathway
PID_REG_GR_PATHWAY	82	60	All SZGR genes in this pathway
PID_TNF_PATHWAY	46	33	All SZGR genes in this pathway
PID_IL2_PI3K_PATHWAY	34	27	All SZGR genes in this pathway
PID_CERAMIDE_PATHWAY	48	37	All SZGR genes in this pathway
PID_IL23_PATHWAY	37	30	All SZGR genes in this pathway
PID_HIV_NEF_PATHWAY	35	26	All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF	217	167	All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY	396	292	All SZGR genes in this pathway
REACTOME_TRIF_MEDIATED_TLR3_SIGNALING	74	54	All SZGR genes in this pathway
REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI	18	15	All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR	97	66	All SZGR genes in this pathway
REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS	64	43	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR	126	90	All SZGR genes in this pathway
REACTOME_TCR_SIGNALING	54	46	All SZGR genes in this pathway
REACTOME_DOWNSTREAM_TCR_SIGNALING	37	32	All SZGR genes in this pathway
REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR	10	9	All SZGR genes in this pathway
REACTOME_P75NTR_SIGNALS_VIA_NFKB	14	10	All SZGR genes in this pathway
REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL	11	8	All SZGR genes in this pathway
REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	81	61	All SZGR genes in this pathway
REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX	23	17	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ILS	107	86	All SZGR genes in this pathway
REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION	21	17	All SZGR genes in this pathway
REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION	77	57	All SZGR genes in this pathway
REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE	72	53	All SZGR genes in this pathway
REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS	73	57	All SZGR genes in this pathway
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION	72	53	All SZGR genes in this pathway
REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE	83	63	All SZGR genes in this pathway
REACTOME_INNATE_IMMUNE_SYSTEM	279	178	All SZGR genes in this pathway
REACTOME_ACTIVATED_TLR4_SIGNALLING	93	69	All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM	933	616	All SZGR genes in this pathway
REACTOME_TOLL_RECEPTOR_CASCADES	118	84	All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM	539	350	All SZGR genes in this pathway
REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM	270	204	All SZGR genes in this pathway
ODONNELL_TFRC_TARGETS_UP	456	228	All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP	544	308	All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LPS_UP	431	237	All SZGR genes in this pathway
MARKS_ACETYLATED_NON_HISTONE_PROTEINS	15	9	All SZGR genes in this pathway
GILMORE_CORE_NFKB_PATHWAY	14	10	All SZGR genes in this pathway
SCHEIDEREIT_IKK_TARGETS	18	15	All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_2	127	92	All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_UP	134	93	All SZGR genes in this pathway
SCHEIDEREIT_IKK_INTERACTING_PROTEINS	58	45	All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_UP	309	199	All SZGR genes in this pathway
TSAI_RESPONSE_TO_IONIZING_RADIATION	149	101	All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN	584	395	All SZGR genes in this pathway
PUJANA_BREAST_CANCER_LIT_INT_NETWORK	101	73	All SZGR genes in this pathway
SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN	31	23	All SZGR genes in this pathway
AMIT_EGF_RESPONSE_480_HELA	164	118	All SZGR genes in this pathway
FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP	87	67	All SZGR genes in this pathway
ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_DN	19	14	All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_20HR_UP	240	152	All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP	244	165	All SZGR genes in this pathway
ZHANG_PROLIFERATING_VS_QUIESCENT	51	41	All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C0	107	72	All SZGR genes in this pathway
JACKSON_DNMT1_TARGETS_UP	77	57	All SZGR genes in this pathway
LEE_CALORIE_RESTRICTION_NEOCORTEX_DN	88	58	All SZGR genes in this pathway
WELCSH_BRCA1_TARGETS_DN	141	92	All SZGR genes in this pathway
KYNG_RESPONSE_TO_H2O2	71	42	All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP	77	47	All SZGR genes in this pathway
LABBE_TARGETS_OF_TGFB1_AND_WNT3A_DN	108	68	All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_UP	245	159	All SZGR genes in this pathway
WINTER_HYPOXIA_METAGENE	242	168	All SZGR genes in this pathway
HINATA_NFKB_TARGETS_KERATINOCYTE_UP	91	63	All SZGR genes in this pathway
HINATA_NFKB_TARGETS_FIBROBLAST_UP	84	60	All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP	430	288	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B	549	316	All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_AND_SATB1_DN	180	116	All SZGR genes in this pathway