Summary ?
GeneID6007
SymbolRHD
SynonymsCD240D|DIIIc|RH|RH30|RHCED|RHDVA(TT)|RHDel|RHPII|RHXIII|Rh4|RhDCw|RhII|RhK562-II|RhPI
DescriptionRh blood group D antigen
ReferenceMIM:111680|HGNC:HGNC:10009|Ensembl:ENSG00000187010|HPRD:00199|Vega:OTTHUMG00000003476
Gene typeprotein-coding
Map location1p36.11
Pascal p-value0.782
Fetal beta0.516
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9
Hippocampus
Hypothalamus
Nucleus accumbens basal ganglia
Putamen basal ganglia

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs55794721125561667RHDENSG00000187010.148.219E-90-37217gtex_brain_ba24
rs72660908125583610RHDENSG00000187010.141.053E-90-15274gtex_brain_ba24
rs9645452125668326RHDENSG00000187010.143.824E-6069442gtex_brain_ba24
rs3093584125668714RHDENSG00000187010.143.852E-6069830gtex_brain_ba24
rs3093614125677844RHDENSG00000187010.144.276E-6078960gtex_brain_ba24
rs630337125724005RHDENSG00000187010.142.416E-70125121gtex_brain_ba24
rs111941366125736369RHDENSG00000187010.142.725E-60137485gtex_brain_ba24
rs909832125754025RHDENSG00000187010.146E-70155141gtex_brain_ba24
rs71808843125816658RHDENSG00000187010.149.934E-70217774gtex_brain_ba24
rs72660960125816847RHDENSG00000187010.141.089E-60217963gtex_brain_ba24
rs72660961125818452RHDENSG00000187010.141.089E-60219568gtex_brain_ba24
rs55794721125561667RHDENSG00000187010.141.877E-100-37217gtex_brain_putamen_basal
rs72660908125583610RHDENSG00000187010.143.2E-100-15274gtex_brain_putamen_basal
rs71652365125610579RHDENSG00000187010.142.395E-6011695gtex_brain_putamen_basal
rs3093578125667911RHDENSG00000187010.143.226E-6069027gtex_brain_putamen_basal
rs9645452125668326RHDENSG00000187010.141.74E-6069442gtex_brain_putamen_basal
rs3093583125668366RHDENSG00000187010.142.651E-6069482gtex_brain_putamen_basal
rs3093584125668714RHDENSG00000187010.141.736E-6069830gtex_brain_putamen_basal
rs3091242125674785RHDENSG00000187010.143.269E-6075901gtex_brain_putamen_basal
rs3091241125674913RHDENSG00000187010.142.381E-6076029gtex_brain_putamen_basal
rs3091240125676935RHDENSG00000187010.143.231E-6078051gtex_brain_putamen_basal
rs3093614125677844RHDENSG00000187010.141.747E-6078960gtex_brain_putamen_basal
rs3093632125684012RHDENSG00000187010.142.903E-6085128gtex_brain_putamen_basal
rs3093638125685484RHDENSG00000187010.141.662E-6086600gtex_brain_putamen_basal
rs1053438125687901RHDENSG00000187010.141.522E-6089017gtex_brain_putamen_basal
rs599691125698354RHDENSG00000187010.141.6E-6099470gtex_brain_putamen_basal
rs614997125703776RHDENSG00000187010.149.701E-70104892gtex_brain_putamen_basal
rs646867125709258RHDENSG00000187010.141.703E-60110374gtex_brain_putamen_basal
rs607116125717841RHDENSG00000187010.149.332E-70118957gtex_brain_putamen_basal
rs665372125719235RHDENSG00000187010.141.763E-60120351gtex_brain_putamen_basal
rs686631125719599RHDENSG00000187010.141.761E-60120715gtex_brain_putamen_basal
rs679879125720204RHDENSG00000187010.142.857E-60121320gtex_brain_putamen_basal
rs630337125724005RHDENSG00000187010.141.359E-60125121gtex_brain_putamen_basal
rs631133125724146RHDENSG00000187010.146.391E-70125262gtex_brain_putamen_basal
rs660129125727438RHDENSG00000187010.141.073E-60128554gtex_brain_putamen_basal
rs706845125730713RHDENSG00000187010.141.657E-60131829gtex_brain_putamen_basal
rs111941366125736369RHDENSG00000187010.142.591E-90137485gtex_brain_putamen_basal
rs12048617125739064RHDENSG00000187010.141.273E-60140180gtex_brain_putamen_basal
rs28633797125741629RHDENSG00000187010.148.089E-70142745gtex_brain_putamen_basal
rs2982360125745645RHDENSG00000187010.141.079E-60146761gtex_brain_putamen_basal
rs2375313125748235RHDENSG00000187010.141.353E-60149351gtex_brain_putamen_basal
rs4649082125748357RHDENSG00000187010.141.056E-60149473gtex_brain_putamen_basal
rs4649084125752617RHDENSG00000187010.141.025E-60153733gtex_brain_putamen_basal
rs909832125754025RHDENSG00000187010.142.773E-100155141gtex_brain_putamen_basal
rs11249249125758134RHDENSG00000187010.143.071E-60159250gtex_brain_putamen_basal
rs35497030125783066RHDENSG00000187010.142.807E-60184182gtex_brain_putamen_basal
rs61775174125787313RHDENSG00000187010.142.817E-60188429gtex_brain_putamen_basal
rs34054126125792915RHDENSG00000187010.142.817E-60194031gtex_brain_putamen_basal
rs61775180125793663RHDENSG00000187010.141.773E-60194779gtex_brain_putamen_basal
rs35850196125794892RHDENSG00000187010.142.817E-60196008gtex_brain_putamen_basal
rs67595476125799681RHDENSG00000187010.142.728E-60200797gtex_brain_putamen_basal
rs61775184125801409RHDENSG00000187010.142.819E-60202525gtex_brain_putamen_basal
rs66844552125802056RHDENSG00000187010.143.254E-60203172gtex_brain_putamen_basal
rs71808843125816658RHDENSG00000187010.142.876E-100217774gtex_brain_putamen_basal
rs72660960125816847RHDENSG00000187010.142.843E-100217963gtex_brain_putamen_basal
rs72660961125818452RHDENSG00000187010.142.843E-100219568gtex_brain_putamen_basal
rs35495923125851977RHDENSG00000187010.147.69E-80253093gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
C1QA0.870.84
C1QB0.860.84
C1QC0.830.81
TBXAS10.820.82
ADORA30.810.79
C3AR10.800.76
SLC2A50.790.71
TYROBP0.790.82
GPR340.790.79
FCER1G0.780.81
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
SAFB2-0.43-0.46
UPF3A-0.42-0.53
TNKS1BP1-0.42-0.43
PABPN1-0.40-0.51
ZNF418-0.40-0.42
TAF15-0.40-0.44
AXIN1-0.39-0.40
ANO8-0.39-0.45
VAV2-0.39-0.41
RBM6-0.39-0.45

Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003674molecular_functionND1438298 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008150biological_processND-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0016021integral to membraneNAS1438298 
GO:0005887integral to plasma membraneTAS1438298 

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
JAATINEN HEMATOPOIETIC STEM CELL DN 226132All SZGR 2.0 genes in this pathway
MORI SMALL PRE BII LYMPHOCYTE DN 7652All SZGR 2.0 genes in this pathway
ALCALAY AML BY NPM1 LOCALIZATION DN 184132All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS MATURE CELL 293160All SZGR 2.0 genes in this pathway
CAMPS COLON CANCER COPY NUMBER DN 7434All SZGR 2.0 genes in this pathway
GOLDRATH ANTIGEN RESPONSE 346192All SZGR 2.0 genes in this pathway
YOSHIMURA MAPK8 TARGETS UP 1305895All SZGR 2.0 genes in this pathway
VALK AML CLUSTER 7 2816All SZGR 2.0 genes in this pathway
VALK AML CLUSTER 8 2617All SZGR 2.0 genes in this pathway
CHYLA CBFA2T3 TARGETS DN 242146All SZGR 2.0 genes in this pathway
ACOSTA PROLIFERATION INDEPENDENT MYC TARGETS DN 11674All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP D 280158All SZGR 2.0 genes in this pathway
DELACROIX RAR BOUND ES 462273All SZGR 2.0 genes in this pathway