Gene Page: EXOC4
Summary ?
| GeneID | 60412 |
| Symbol | EXOC4 |
| Synonyms | SEC8|SEC8L1|Sec8p |
| Description | exocyst complex component 4 |
| Reference | MIM:608185|HGNC:HGNC:30389|Ensembl:ENSG00000131558|HPRD:12185|Vega:OTTHUMG00000155259 |
| Gene type | protein-coding |
| Map location | 7q31 |
| Pascal p-value | 0.04 |
| Sherlock p-value | 0.499 |
| Fetal beta | 0.927 |
| eGene | Anterior cingulate cortex BA24 Cerebellar Hemisphere Cerebellum |
| Support | EXOCYTOSIS G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS G2Cdb.humanPSD G2Cdb.humanPSP CompositeSet Potential synaptic genes |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
| Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 2.2747 |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs113786846 | 7 | 133130566 | EXOC4 | ENSG00000131558.10 | 1.21E-6 | 0 | 192737 | gtex_brain_ba24 |
| rs75486675 | 7 | 133275161 | EXOC4 | ENSG00000131558.10 | 1.838E-6 | 0 | 337332 | gtex_brain_ba24 |
| rs143627085 | 7 | 133298906 | EXOC4 | ENSG00000131558.10 | 1.809E-6 | 0 | 361077 | gtex_brain_ba24 |
| rs17167181 | 7 | 133320251 | EXOC4 | ENSG00000131558.10 | 1.776E-6 | 0 | 382422 | gtex_brain_ba24 |
| rs57155904 | 7 | 133339938 | EXOC4 | ENSG00000131558.10 | 6.39E-7 | 0 | 402109 | gtex_brain_ba24 |
| rs10234061 | 7 | 133340194 | EXOC4 | ENSG00000131558.10 | 9.751E-7 | 0 | 402365 | gtex_brain_ba24 |
| rs10263870 | 7 | 133340248 | EXOC4 | ENSG00000131558.10 | 9.668E-7 | 0 | 402419 | gtex_brain_ba24 |
| rs73726943 | 7 | 133341144 | EXOC4 | ENSG00000131558.10 | 9.366E-7 | 0 | 403315 | gtex_brain_ba24 |
| rs73150859 | 7 | 133341262 | EXOC4 | ENSG00000131558.10 | 2.324E-6 | 0 | 403433 | gtex_brain_ba24 |
| rs10274470 | 7 | 133344573 | EXOC4 | ENSG00000131558.10 | 1.049E-6 | 0 | 406744 | gtex_brain_ba24 |
| rs10271234 | 7 | 133347354 | EXOC4 | ENSG00000131558.10 | 9.483E-7 | 0 | 409525 | gtex_brain_ba24 |
| rs12113650 | 7 | 133352719 | EXOC4 | ENSG00000131558.10 | 2.277E-6 | 0 | 414890 | gtex_brain_ba24 |
| rs373201432 | 7 | 133355999 | EXOC4 | ENSG00000131558.10 | 2.309E-6 | 0 | 418170 | gtex_brain_ba24 |
| rs113495600 | 7 | 133356091 | EXOC4 | ENSG00000131558.10 | 2.309E-6 | 0 | 418262 | gtex_brain_ba24 |
| rs59821244 | 7 | 133360731 | EXOC4 | ENSG00000131558.10 | 2.312E-6 | 0 | 422902 | gtex_brain_ba24 |
| rs10263225 | 7 | 133360867 | EXOC4 | ENSG00000131558.10 | 9.65E-7 | 0 | 423038 | gtex_brain_ba24 |
| rs12113622 | 7 | 133362796 | EXOC4 | ENSG00000131558.10 | 2.308E-6 | 0 | 424967 | gtex_brain_ba24 |
| rs57597668 | 7 | 133363580 | EXOC4 | ENSG00000131558.10 | 9.65E-7 | 0 | 425751 | gtex_brain_ba24 |
| rs73150882 | 7 | 133372355 | EXOC4 | ENSG00000131558.10 | 2.308E-6 | 0 | 434526 | gtex_brain_ba24 |
| rs73724712 | 7 | 133380896 | EXOC4 | ENSG00000131558.10 | 2.308E-6 | 0 | 443067 | gtex_brain_ba24 |
| rs55696747 | 7 | 133381888 | EXOC4 | ENSG00000131558.10 | 2.308E-6 | 0 | 444059 | gtex_brain_ba24 |
| rs60147418 | 7 | 133381965 | EXOC4 | ENSG00000131558.10 | 2.308E-6 | 0 | 444136 | gtex_brain_ba24 |
| rs59834203 | 7 | 133390669 | EXOC4 | ENSG00000131558.10 | 9.583E-7 | 0 | 452840 | gtex_brain_ba24 |
| rs73150889 | 7 | 133396822 | EXOC4 | ENSG00000131558.10 | 2.274E-6 | 0 | 458993 | gtex_brain_ba24 |
| rs10274328 | 7 | 133409403 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 471574 | gtex_brain_ba24 |
| rs1362736 | 7 | 133409869 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 472040 | gtex_brain_ba24 |
| rs1362737 | 7 | 133409952 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 472123 | gtex_brain_ba24 |
| rs12113384 | 7 | 133411133 | EXOC4 | ENSG00000131558.10 | 1.432E-6 | 0 | 473304 | gtex_brain_ba24 |
| rs11761911 | 7 | 133414793 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 476964 | gtex_brain_ba24 |
| rs55842945 | 7 | 133416304 | EXOC4 | ENSG00000131558.10 | 1.617E-6 | 0 | 478475 | gtex_brain_ba24 |
| rs6947583 | 7 | 133417287 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 479458 | gtex_brain_ba24 |
| rs10273626 | 7 | 133418005 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 480176 | gtex_brain_ba24 |
| rs56734859 | 7 | 133421638 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 483809 | gtex_brain_ba24 |
| rs10267901 | 7 | 133421879 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 484050 | gtex_brain_ba24 |
| rs73150897 | 7 | 133422687 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 484858 | gtex_brain_ba24 |
| rs7784822 | 7 | 133422963 | EXOC4 | ENSG00000131558.10 | 3.805E-7 | 0 | 485134 | gtex_brain_ba24 |
| rs2111522 | 7 | 133424377 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 486548 | gtex_brain_ba24 |
| rs73150902 | 7 | 133425220 | EXOC4 | ENSG00000131558.10 | 1.432E-6 | 0 | 487391 | gtex_brain_ba24 |
| rs73724727 | 7 | 133428481 | EXOC4 | ENSG00000131558.10 | 1.577E-6 | 0 | 490652 | gtex_brain_ba24 |
| rs73152912 | 7 | 133433486 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 495657 | gtex_brain_ba24 |
| rs9649047 | 7 | 133433514 | EXOC4 | ENSG00000131558.10 | 4.628E-7 | 0 | 495685 | gtex_brain_ba24 |
| rs10257034 | 7 | 133435149 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 497320 | gtex_brain_ba24 |
| rs73152913 | 7 | 133435296 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 497467 | gtex_brain_ba24 |
| rs10274627 | 7 | 133435750 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 497921 | gtex_brain_ba24 |
| rs10246101 | 7 | 133436485 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 498656 | gtex_brain_ba24 |
| rs73152915 | 7 | 133440385 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 502556 | gtex_brain_ba24 |
| rs985101 | 7 | 133441165 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 503336 | gtex_brain_ba24 |
| rs7797067 | 7 | 133441408 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 503579 | gtex_brain_ba24 |
| rs766294 | 7 | 133443181 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 505352 | gtex_brain_ba24 |
| rs140420843 | 7 | 133443452 | EXOC4 | ENSG00000131558.10 | 1.432E-6 | 0 | 505623 | gtex_brain_ba24 |
| rs73152917 | 7 | 133444857 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 507028 | gtex_brain_ba24 |
| rs6467504 | 7 | 133446879 | EXOC4 | ENSG00000131558.10 | 5.683E-7 | 0 | 509050 | gtex_brain_ba24 |
| rs60848374 | 7 | 133448812 | EXOC4 | ENSG00000131558.10 | 5.683E-7 | 0 | 510983 | gtex_brain_ba24 |
| rs7810078 | 7 | 133448958 | EXOC4 | ENSG00000131558.10 | 5.683E-7 | 0 | 511129 | gtex_brain_ba24 |
| rs10954432 | 7 | 133449916 | EXOC4 | ENSG00000131558.10 | 5.683E-7 | 0 | 512087 | gtex_brain_ba24 |
| rs56922033 | 7 | 133450134 | EXOC4 | ENSG00000131558.10 | 5.683E-7 | 0 | 512305 | gtex_brain_ba24 |
| rs1895024 | 7 | 133454333 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 516504 | gtex_brain_ba24 |
| rs73152978 | 7 | 133455493 | EXOC4 | ENSG00000131558.10 | 5.663E-7 | 0 | 517664 | gtex_brain_ba24 |
| rs58642167 | 7 | 133456632 | EXOC4 | ENSG00000131558.10 | 6.399E-7 | 0 | 518803 | gtex_brain_ba24 |
| rs16874343 | 7 | 133457820 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 519991 | gtex_brain_ba24 |
| rs7810739 | 7 | 133458524 | EXOC4 | ENSG00000131558.10 | 3.779E-7 | 0 | 520695 | gtex_brain_ba24 |
| rs7778582 | 7 | 133458754 | EXOC4 | ENSG00000131558.10 | 4.817E-7 | 0 | 520925 | gtex_brain_ba24 |
| rs1420969 | 7 | 133459301 | EXOC4 | ENSG00000131558.10 | 4.814E-7 | 0 | 521472 | gtex_brain_ba24 |
| rs4731981 | 7 | 133459465 | EXOC4 | ENSG00000131558.10 | 4.814E-7 | 0 | 521636 | gtex_brain_ba24 |
| rs10582253 | 7 | 133460981 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 523152 | gtex_brain_ba24 |
| rs10276313 | 7 | 133461226 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 523397 | gtex_brain_ba24 |
| rs10262452 | 7 | 133461259 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 523430 | gtex_brain_ba24 |
| rs10266990 | 7 | 133461890 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 524061 | gtex_brain_ba24 |
| rs2542255 | 7 | 133462958 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 525129 | gtex_brain_ba24 |
| rs2542256 | 7 | 133463114 | EXOC4 | ENSG00000131558.10 | 2.461E-7 | 0 | 525285 | gtex_brain_ba24 |
| rs17167259 | 7 | 133464907 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 527078 | gtex_brain_ba24 |
| rs73152980 | 7 | 133464988 | EXOC4 | ENSG00000131558.10 | 4.352E-7 | 0 | 527159 | gtex_brain_ba24 |
| rs16874347 | 7 | 133465147 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 527318 | gtex_brain_ba24 |
| rs1073158 | 7 | 133466008 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 528179 | gtex_brain_ba24 |
| rs10488173 | 7 | 133466163 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 528334 | gtex_brain_ba24 |
| rs2160744 | 7 | 133466224 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 528395 | gtex_brain_ba24 |
| rs73152983 | 7 | 133466446 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 528617 | gtex_brain_ba24 |
| rs17167263 | 7 | 133466649 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 528820 | gtex_brain_ba24 |
| rs888309 | 7 | 133466750 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 528921 | gtex_brain_ba24 |
| rs7809238 | 7 | 133468327 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 530498 | gtex_brain_ba24 |
| rs12112614 | 7 | 133473105 | EXOC4 | ENSG00000131558.10 | 5.865E-8 | 0 | 535276 | gtex_brain_ba24 |
| rs34899279 | 7 | 133474622 | EXOC4 | ENSG00000131558.10 | 1.339E-6 | 0 | 536793 | gtex_brain_ba24 |
| rs1476118 | 7 | 133474772 | EXOC4 | ENSG00000131558.10 | 1.319E-6 | 0 | 536943 | gtex_brain_ba24 |
| rs1005342 | 7 | 133476680 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 538851 | gtex_brain_ba24 |
| rs117911788 | 7 | 133477230 | EXOC4 | ENSG00000131558.10 | 1.319E-6 | 0 | 539401 | gtex_brain_ba24 |
| rs2551019 | 7 | 133480783 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 542954 | gtex_brain_ba24 |
| rs73152990 | 7 | 133481070 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 543241 | gtex_brain_ba24 |
| rs56303058 | 7 | 133483845 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 546016 | gtex_brain_ba24 |
| rs2542266 | 7 | 133485193 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 547364 | gtex_brain_ba24 |
| rs2542268 | 7 | 133485802 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 547973 | gtex_brain_ba24 |
| rs2542269 | 7 | 133486184 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 548355 | gtex_brain_ba24 |
| rs10488174 | 7 | 133486837 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 549008 | gtex_brain_ba24 |
| rs1012328 | 7 | 133488775 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 550946 | gtex_brain_ba24 |
| rs12113810 | 7 | 133489115 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 551286 | gtex_brain_ba24 |
| rs17167278 | 7 | 133489358 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 551529 | gtex_brain_ba24 |
| rs17167280 | 7 | 133489419 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 551590 | gtex_brain_ba24 |
| rs1125227 | 7 | 133489490 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 551661 | gtex_brain_ba24 |
| rs2542272 | 7 | 133489612 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 551783 | gtex_brain_ba24 |
| rs55759652 | 7 | 133489616 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 551787 | gtex_brain_ba24 |
| rs17167284 | 7 | 133489691 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 551862 | gtex_brain_ba24 |
| rs56225759 | 7 | 133489760 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 551931 | gtex_brain_ba24 |
| rs2542273 | 7 | 133490084 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 552255 | gtex_brain_ba24 |
| rs2551010 | 7 | 133490571 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 552742 | gtex_brain_ba24 |
| rs723689 | 7 | 133490821 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 552992 | gtex_brain_ba24 |
| rs2551009 | 7 | 133491109 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 553280 | gtex_brain_ba24 |
| rs2551007 | 7 | 133492409 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 554580 | gtex_brain_ba24 |
| rs7783396 | 7 | 133492994 | EXOC4 | ENSG00000131558.10 | 1.319E-6 | 0 | 555165 | gtex_brain_ba24 |
| rs17167290 | 7 | 133493051 | EXOC4 | ENSG00000131558.10 | 1.319E-6 | 0 | 555222 | gtex_brain_ba24 |
| rs10488175 | 7 | 133494257 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 556428 | gtex_brain_ba24 |
| rs2542276 | 7 | 133494751 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 556922 | gtex_brain_ba24 |
| rs2551003 | 7 | 133495625 | EXOC4 | ENSG00000131558.10 | 3.912E-7 | 0 | 557796 | gtex_brain_ba24 |
| rs17167292 | 7 | 133495693 | EXOC4 | ENSG00000131558.10 | 1.319E-6 | 0 | 557864 | gtex_brain_ba24 |
| rs2550999 | 7 | 133496049 | EXOC4 | ENSG00000131558.10 | 4.886E-7 | 0 | 558220 | gtex_brain_ba24 |
| rs2550998 | 7 | 133496633 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 558804 | gtex_brain_ba24 |
| rs72496418 | 7 | 133497349 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 559520 | gtex_brain_ba24 |
| rs2550995 | 7 | 133497610 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 559781 | gtex_brain_ba24 |
| rs73155104 | 7 | 133497842 | EXOC4 | ENSG00000131558.10 | 1.319E-6 | 0 | 560013 | gtex_brain_ba24 |
| rs2550994 | 7 | 133497959 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 560130 | gtex_brain_ba24 |
| rs73155106 | 7 | 133498003 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 560174 | gtex_brain_ba24 |
| rs61427426 | 7 | 133498736 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 560907 | gtex_brain_ba24 |
| rs2550991 | 7 | 133499095 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 561266 | gtex_brain_ba24 |
| rs2550990 | 7 | 133499279 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 561450 | gtex_brain_ba24 |
| rs2550988 | 7 | 133500691 | EXOC4 | ENSG00000131558.10 | 4.242E-7 | 0 | 562862 | gtex_brain_ba24 |
| rs12111749 | 7 | 133501720 | EXOC4 | ENSG00000131558.10 | 3.487E-7 | 0 | 563891 | gtex_brain_ba24 |
| rs1834117 | 7 | 133502828 | EXOC4 | ENSG00000131558.10 | 3.487E-7 | 0 | 564999 | gtex_brain_ba24 |
| rs73155111 | 7 | 133511501 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 573672 | gtex_brain_ba24 |
| rs11489674 | 7 | 133511635 | EXOC4 | ENSG00000131558.10 | 1.319E-6 | 0 | 573806 | gtex_brain_ba24 |
| rs11489675 | 7 | 133511888 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 574059 | gtex_brain_ba24 |
| rs11487150 | 7 | 133512265 | EXOC4 | ENSG00000131558.10 | 4.852E-7 | 0 | 574436 | gtex_brain_ba24 |
| rs55794894 | 7 | 133516821 | EXOC4 | ENSG00000131558.10 | 2.697E-6 | 0 | 578992 | gtex_brain_ba24 |
| rs73155113 | 7 | 133518680 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 580851 | gtex_brain_ba24 |
| rs73155114 | 7 | 133518781 | EXOC4 | ENSG00000131558.10 | 1.319E-6 | 0 | 580952 | gtex_brain_ba24 |
| rs17167304 | 7 | 133525615 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 587786 | gtex_brain_ba24 |
| rs111996039 | 7 | 133527381 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 589552 | gtex_brain_ba24 |
| rs17167306 | 7 | 133529648 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 591819 | gtex_brain_ba24 |
| rs202052617 | 7 | 133530083 | EXOC4 | ENSG00000131558.10 | 1.123E-6 | 0 | 592254 | gtex_brain_ba24 |
| rs73724787 | 7 | 133530806 | EXOC4 | ENSG00000131558.10 | 2.444E-6 | 0 | 592977 | gtex_brain_ba24 |
| rs73155115 | 7 | 133532433 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 594604 | gtex_brain_ba24 |
| rs57448800 | 7 | 133533066 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 595237 | gtex_brain_ba24 |
| rs55796860 | 7 | 133534479 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 596650 | gtex_brain_ba24 |
| rs34470225 | 7 | 133535395 | EXOC4 | ENSG00000131558.10 | 2.594E-6 | 0 | 597566 | gtex_brain_ba24 |
| rs57234431 | 7 | 133535576 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 597747 | gtex_brain_ba24 |
| rs58451591 | 7 | 133536426 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 598597 | gtex_brain_ba24 |
| rs6979346 | 7 | 133537638 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 599809 | gtex_brain_ba24 |
| rs60919451 | 7 | 133538301 | EXOC4 | ENSG00000131558.10 | 1.319E-6 | 0 | 600472 | gtex_brain_ba24 |
| rs71878688 | 7 | 133540389 | EXOC4 | ENSG00000131558.10 | 1.319E-6 | 0 | 602560 | gtex_brain_ba24 |
| rs62470396 | 7 | 133541625 | EXOC4 | ENSG00000131558.10 | 8.085E-8 | 0 | 603796 | gtex_brain_ba24 |
| rs62470397 | 7 | 133541628 | EXOC4 | ENSG00000131558.10 | 8.085E-8 | 0 | 603799 | gtex_brain_ba24 |
| rs62470398 | 7 | 133541630 | EXOC4 | ENSG00000131558.10 | 4.591E-7 | 0 | 603801 | gtex_brain_ba24 |
| rs73155122 | 7 | 133542622 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 604793 | gtex_brain_ba24 |
| rs371088234 | 7 | 133545620 | EXOC4 | ENSG00000131558.10 | 1.319E-6 | 0 | 607791 | gtex_brain_ba24 |
| rs17167308 | 7 | 133551324 | EXOC4 | ENSG00000131558.10 | 1.401E-6 | 0 | 613495 | gtex_brain_ba24 |
| rs73155128 | 7 | 133551529 | EXOC4 | ENSG00000131558.10 | 1.401E-6 | 0 | 613700 | gtex_brain_ba24 |
| rs73155129 | 7 | 133551835 | EXOC4 | ENSG00000131558.10 | 5.139E-7 | 0 | 614006 | gtex_brain_ba24 |
| rs73155130 | 7 | 133551909 | EXOC4 | ENSG00000131558.10 | 5.139E-7 | 0 | 614080 | gtex_brain_ba24 |
| rs73155132 | 7 | 133551924 | EXOC4 | ENSG00000131558.10 | 1.401E-6 | 0 | 614095 | gtex_brain_ba24 |
| rs6954472 | 7 | 133553977 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 616148 | gtex_brain_ba24 |
| rs6955227 | 7 | 133554448 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 616619 | gtex_brain_ba24 |
| rs6955511 | 7 | 133554498 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 616669 | gtex_brain_ba24 |
| rs6979717 | 7 | 133554746 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 616917 | gtex_brain_ba24 |
| rs17167309 | 7 | 133555720 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 617891 | gtex_brain_ba24 |
| rs73155194 | 7 | 133555901 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 618072 | gtex_brain_ba24 |
| rs17167313 | 7 | 133557070 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 619241 | gtex_brain_ba24 |
| rs56084002 | 7 | 133557173 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 619344 | gtex_brain_ba24 |
| rs56375275 | 7 | 133557827 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 619998 | gtex_brain_ba24 |
| rs17167314 | 7 | 133558030 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 620201 | gtex_brain_ba24 |
| rs73155198 | 7 | 133559431 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 621602 | gtex_brain_ba24 |
| rs17167315 | 7 | 133559973 | EXOC4 | ENSG00000131558.10 | 4.76E-7 | 0 | 622144 | gtex_brain_ba24 |
| rs17167317 | 7 | 133560316 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 622487 | gtex_brain_ba24 |
| rs17167318 | 7 | 133560498 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 622669 | gtex_brain_ba24 |
| rs60017847 | 7 | 133560510 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 622681 | gtex_brain_ba24 |
| rs56011565 | 7 | 133561436 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 623607 | gtex_brain_ba24 |
| rs56361791 | 7 | 133562961 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 625132 | gtex_brain_ba24 |
| rs57390458 | 7 | 133562979 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 625150 | gtex_brain_ba24 |
| rs11487001 | 7 | 133563475 | EXOC4 | ENSG00000131558.10 | 1.346E-7 | 0 | 625646 | gtex_brain_ba24 |
| rs11487002 | 7 | 133563501 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 625672 | gtex_brain_ba24 |
| rs113546677 | 7 | 133563537 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 625708 | gtex_brain_ba24 |
| rs11487003 | 7 | 133563880 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 626051 | gtex_brain_ba24 |
| rs11489543 | 7 | 133563999 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 626170 | gtex_brain_ba24 |
| rs7791645 | 7 | 133564857 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 627028 | gtex_brain_ba24 |
| rs7792636 | 7 | 133565306 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 627477 | gtex_brain_ba24 |
| rs17167330 | 7 | 133566579 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 628750 | gtex_brain_ba24 |
| rs56358145 | 7 | 133569164 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 631335 | gtex_brain_ba24 |
| rs17167332 | 7 | 133569556 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 631727 | gtex_brain_ba24 |
| rs7800371 | 7 | 133570026 | EXOC4 | ENSG00000131558.10 | 3.956E-7 | 0 | 632197 | gtex_brain_ba24 |
| rs73156904 | 7 | 133570313 | EXOC4 | ENSG00000131558.10 | 1.332E-7 | 0 | 632484 | gtex_brain_ba24 |
| rs17167333 | 7 | 133571646 | EXOC4 | ENSG00000131558.10 | 4.031E-7 | 0 | 633817 | gtex_brain_ba24 |
| rs16874350 | 7 | 133573084 | EXOC4 | ENSG00000131558.10 | 3.978E-7 | 0 | 635255 | gtex_brain_ba24 |
| rs55886636 | 7 | 133573780 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 635951 | gtex_brain_ba24 |
| rs7810566 | 7 | 133581202 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 643373 | gtex_brain_ba24 |
| rs73156915 | 7 | 133581379 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 643550 | gtex_brain_ba24 |
| rs7810870 | 7 | 133581473 | EXOC4 | ENSG00000131558.10 | 3.927E-7 | 0 | 643644 | gtex_brain_ba24 |
| rs199587368 | 7 | 133582000 | EXOC4 | ENSG00000131558.10 | 1.902E-6 | 0 | 644171 | gtex_brain_ba24 |
| rs56067609 | 7 | 133582465 | EXOC4 | ENSG00000131558.10 | 4.026E-7 | 0 | 644636 | gtex_brain_ba24 |
| rs56170554 | 7 | 133582990 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 645161 | gtex_brain_ba24 |
| rs17167335 | 7 | 133585050 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 647221 | gtex_brain_ba24 |
| rs73156925 | 7 | 133586346 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 648517 | gtex_brain_ba24 |
| rs17167336 | 7 | 133586703 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 648874 | gtex_brain_ba24 |
| rs5887649 | 7 | 133598999 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 661170 | gtex_brain_ba24 |
| rs10488180 | 7 | 133600277 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 662448 | gtex_brain_ba24 |
| rs73156933 | 7 | 133602116 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 664287 | gtex_brain_ba24 |
| rs73156934 | 7 | 133602538 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 664709 | gtex_brain_ba24 |
| rs56225573 | 7 | 133606451 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 668622 | gtex_brain_ba24 |
| rs10251286 | 7 | 133607914 | EXOC4 | ENSG00000131558.10 | 1.38E-6 | 0 | 670085 | gtex_brain_ba24 |
| rs73156938 | 7 | 133608265 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 670436 | gtex_brain_ba24 |
| rs73156939 | 7 | 133608447 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 670618 | gtex_brain_ba24 |
| rs73156940 | 7 | 133610266 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 672437 | gtex_brain_ba24 |
| rs10428917 | 7 | 133615010 | EXOC4 | ENSG00000131558.10 | 3.971E-7 | 0 | 677181 | gtex_brain_ba24 |
| rs55655901 | 7 | 133620194 | EXOC4 | ENSG00000131558.10 | 3.966E-7 | 0 | 682365 | gtex_brain_ba24 |
| rs73156959 | 7 | 133639832 | EXOC4 | ENSG00000131558.10 | 2.697E-6 | 0 | 702003 | gtex_brain_ba24 |
| rs139402430 | 7 | 133728363 | EXOC4 | ENSG00000131558.10 | 1.101E-6 | 0 | 790534 | gtex_brain_ba24 |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | - | |
| GO:0005515 | protein binding | IPI | 18329369 | |
| GO:0005524 | ATP binding | IEA | - | |
| GO:0030165 | PDZ domain binding | IEA | - | |
| GO:0008026 | ATP-dependent helicase activity | IEA | - | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0006904 | vesicle docking during exocytosis | IEA | - | |
| GO:0015031 | protein transport | IEA | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0000145 | exocyst | IEA | - | |
| GO:0005737 | cytoplasm | IDA | 11256614 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG TIGHT JUNCTION | 134 | 86 | All SZGR 2.0 genes in this pathway |
| PID INSULIN PATHWAY | 45 | 32 | All SZGR 2.0 genes in this pathway |
| PID ARF6 TRAFFICKING PATHWAY | 49 | 34 | All SZGR 2.0 genes in this pathway |
| PID ECADHERIN STABILIZATION PATHWAY | 42 | 34 | All SZGR 2.0 genes in this pathway |
| REACTOME DIABETES PATHWAYS | 133 | 91 | All SZGR 2.0 genes in this pathway |
| REACTOME INSULIN SYNTHESIS AND PROCESSING | 21 | 15 | All SZGR 2.0 genes in this pathway |
| CHEMNITZ RESPONSE TO PROSTAGLANDIN E2 DN | 391 | 222 | All SZGR 2.0 genes in this pathway |
| WANG LMO4 TARGETS DN | 352 | 225 | All SZGR 2.0 genes in this pathway |
| CASTELLANO NRAS TARGETS UP | 68 | 41 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN UP | 1142 | 669 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN RESPONSE TO MC AND DOXORUBICIN UP | 612 | 367 | All SZGR 2.0 genes in this pathway |
| MARTORIATI MDM4 TARGETS NEUROEPITHELIUM UP | 176 | 111 | All SZGR 2.0 genes in this pathway |
| MARTORIATI MDM4 TARGETS FETAL LIVER UP | 227 | 137 | All SZGR 2.0 genes in this pathway |
| KOYAMA SEMA3B TARGETS DN | 411 | 249 | All SZGR 2.0 genes in this pathway |
| BENPORATH NANOG TARGETS | 988 | 594 | All SZGR 2.0 genes in this pathway |
| AFFAR YY1 TARGETS UP | 214 | 133 | All SZGR 2.0 genes in this pathway |
| BURTON ADIPOGENESIS 9 | 92 | 59 | All SZGR 2.0 genes in this pathway |
| ZHANG TLX TARGETS 36HR UP | 221 | 150 | All SZGR 2.0 genes in this pathway |
| ZHANG TLX TARGETS 60HR UP | 293 | 203 | All SZGR 2.0 genes in this pathway |
| ZHANG TLX TARGETS UP | 108 | 78 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN ES ICP WITH H3K4ME3 | 718 | 401 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN NPC ICP WITH H3K4ME3 | 445 | 257 | All SZGR 2.0 genes in this pathway |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 12 | 79 | 54 | All SZGR 2.0 genes in this pathway |
Section VI. microRNA annotation
| miRNA family | Target position | miRNA ID | miRNA seq | ||
|---|---|---|---|---|---|
| UTR start | UTR end | Match method | |||
| miR-182 | 498 | 505 | 1A,m8 | hsa-miR-182 | UUUGGCAAUGGUAGAACUCACA |
- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.