Gene Page: SFRP2

Summary ?
GeneID6423
SymbolSFRP2
SynonymsFRP-2|SARP1|SDF-5
Descriptionsecreted frizzled-related protein 2
ReferenceMIM:604157|HGNC:HGNC:10777|Ensembl:ENSG00000145423|HPRD:16041|Vega:OTTHUMG00000161559
Gene typeprotein-coding
Map location4q31.3
Pascal p-value0.006
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs954368chr4154771775SFRP264230.07cis
rs6820559chr4154813698SFRP264230.03cis
rs17131472chr191962966SFRP264233.305E-4trans
rs546975chr191963738SFRP264230.13trans
rs10218671chr1158362552SFRP264230.18trans
rs1835319chr216586056SFRP264230.05trans
rs6710894chr266876700SFRP264230.16trans
rs17821815chr2119018522SFRP264230.01trans
rs2115055chr2119478688SFRP264230.14trans
rs11679772chr2158292302SFRP264230.19trans
rs1691463chr384914366SFRP264230.07trans
rs2922180chr3125280472SFRP264235.172E-8trans
rs2971271chr3125450402SFRP264230.08trans
rs2976809chr3125451738SFRP264231.059E-5trans
rs16889842chr49872012SFRP264230.05trans
rs17776097chr490247162SFRP264230.19trans
rs4033102chr4111784204SFRP264230.03trans
rs509952chr4111788169SFRP264230.02trans
rs313946chr4113975904SFRP264230.01trans
rs10050805chr530805352SFRP264230.01trans
rs16894149chr561013724SFRP264230.15trans
rs17143695chr5117520843SFRP264230.14trans
rs6874540chr5149911669SFRP264230.15trans
rs2273232chr5149912526SFRP264230.15trans
rs11954814chr5155088338SFRP264230.12trans
rs17056435chr5158453782SFRP264232.686E-4trans
rs12663807chr640571873SFRP264230.02trans
rs6920042chr667907570SFRP264230.16trans
rs6455226chr667930295SFRP264230trans
rs16868852chr670980333SFRP264230.18trans
rs283058chr6118625224SFRP264230trans
rs12216440chr6118856821SFRP264230.11trans
rs2056744chr6144952933SFRP264230.12trans
rs2430483chr7104548631SFRP264230.01trans
rs10273901chr7131828566SFRP264230.13trans
rs2199402chr89201002SFRP264230.06trans
rs7841407chr89243427SFRP264230trans
rs2739708chr817992280SFRP264230.03trans
rs714131chr817992832SFRP264230.09trans
rs2739726chr817998576SFRP264230.02trans
rs2919377chr832573740SFRP264230.01trans
rs680372chr836999626SFRP264230.19trans
rs7850851chr937928770SFRP264230.12trans
rs2253777chr993467893SFRP264230.04trans
rs998410chr9117622673SFRP264230.09trans
rs9423711chr102574802SFRP264232.521E-6trans
rs2388266chr102595037SFRP264230.1trans
rs651134chr1027549960SFRP264230.09trans
rs748375chr1033440178SFRP264230.08trans
rs4514358chr1043861923SFRP264230.02trans
rs7081666chr1047673800SFRP264230.01trans
rs10488758chr11103493095SFRP264230.09trans
rs1905067chr11103493989SFRP264230.15trans
rs11225990chr11103608380SFRP264230.1trans
rs2305164chr12365649SFRP264230.03trans
rs107479720SFRP264230.18trans
rs995817chr1267557935SFRP264230.15trans
rs10879027chr1270237156SFRP264232.408E-4trans
rs11112163chr12105072508SFRP264230.16trans
rs17080889chr1320939135SFRP264230.17trans
rs9551590chr1329589464SFRP264230.04trans
rs9532792chr1341912654SFRP264230.15trans
rs9590586chr1341913130SFRP264230.17trans
rs7358853chr1341931685SFRP264230.19trans
rs8002343chr1341952090SFRP264230.17trans
rs9315839chr1341952872SFRP264230.19trans
rs7982172chr1341969697SFRP264230.16trans
rs4942043chr1341978218SFRP264230.03trans
rs4402447chr1341984741SFRP264230.16trans
rs7982922chr1343873335SFRP264230.18trans
rs9529974chr1372821935SFRP264233.814E-4trans
rs17073665chr1381541961SFRP264230trans
rs11840833chr1394378306SFRP264230.01trans
rs16975617chr13110867407SFRP264230.06trans
rs10142086chr1435135892SFRP264230.15trans
rs1956517chr1437738426SFRP264230.12trans
rs1457420chr1466958675SFRP264230.12trans
rs2093759chr1497171024SFRP264230trans
rs17244419chr1497171074SFRP264234.182E-5trans
rs7177212chr1534425413SFRP264230.19trans
rs16976022chr1555454260SFRP264230.07trans
rs16976029chr1555455268SFRP264230.03trans
rs16976036chr1555456921SFRP264230.04trans
rs8034402chr1555480932SFRP264230.1trans
rs11073814chr1589378883SFRP264230.18trans
rs7165622chr1593979910SFRP264230.1trans
rs13380712chr1625601181SFRP264230.04trans
rs17841422chr1720969134SFRP264230trans
rs16977927chr1772154232SFRP264230.05trans
rs16940550chr1813442256SFRP264230.19trans
rs7236104chr1814032818SFRP264230.14trans
rs9949772chr1831042632SFRP264230.1trans
rs7236407chr1847827597SFRP264230.1trans
rs4987765chr1860905021SFRP264230.06trans
rs11873703chr1861448702SFRP264236.602E-6trans
rs6095741chr2048666589SFRP264231.186E-10trans
rs6004906chr2226434554SFRP264230.04trans
rs6000401chr2237149335SFRP264230.13trans
rs5991662chrX43335796SFRP264235.443E-5trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG WNT SIGNALING PATHWAY 151112All SZGR 2.0 genes in this pathway
SENGUPTA NASOPHARYNGEAL CARCINOMA WITH LMP1 UP 408247All SZGR 2.0 genes in this pathway
TURASHVILI BREAST DUCTAL CARCINOMA VS DUCTAL NORMAL UP 4425All SZGR 2.0 genes in this pathway
TURASHVILI BREAST LOBULAR CARCINOMA VS DUCTAL NORMAL UP 6938All SZGR 2.0 genes in this pathway
TURASHVILI BREAST LOBULAR CARCINOMA VS LOBULAR NORMAL DN 7442All SZGR 2.0 genes in this pathway
NOJIMA SFRP2 TARGETS UP 3123All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER ADVANCED VS EARLY UP 175120All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION UP 1278748All SZGR 2.0 genes in this pathway
MARKEY RB1 CHRONIC LOF UP 11578All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS E UP 9760All SZGR 2.0 genes in this pathway
BERENJENO TRANSFORMED BY RHOA DN 394258All SZGR 2.0 genes in this pathway
HATADA METHYLATED IN LUNG CANCER UP 390236All SZGR 2.0 genes in this pathway
LIEN BREAST CARCINOMA METAPLASTIC 3525All SZGR 2.0 genes in this pathway
SCHLESINGER METHYLATED IN COLON CANCER 107All SZGR 2.0 genes in this pathway
OHM METHYLATED IN ADULT CANCERS 2723All SZGR 2.0 genes in this pathway
OHM EMBRYONIC CARCINOMA UP 65All SZGR 2.0 genes in this pathway
INGRAM SHH TARGETS DN 6441All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 12HR UP 11679All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR UP 487286All SZGR 2.0 genes in this pathway
BENPORATH ES 1 379235All SZGR 2.0 genes in this pathway
BENPORATH NANOG TARGETS 988594All SZGR 2.0 genes in this pathway
BENPORATH OCT4 TARGETS 290172All SZGR 2.0 genes in this pathway
BENPORATH SOX2 TARGETS 734436All SZGR 2.0 genes in this pathway
BENPORATH NOS TARGETS 179105All SZGR 2.0 genes in this pathway
UEDA CENTRAL CLOCK 8862All SZGR 2.0 genes in this pathway
BHATTACHARYA EMBRYONIC STEM CELL 8960All SZGR 2.0 genes in this pathway
GUO HEX TARGETS UP 8154All SZGR 2.0 genes in this pathway
MATSUDA NATURAL KILLER DIFFERENTIATION 475313All SZGR 2.0 genes in this pathway
ZHAN MULTIPLE MYELOMA MF UP 4727All SZGR 2.0 genes in this pathway
WANG SMARCE1 TARGETS DN 371218All SZGR 2.0 genes in this pathway
PAL PRMT5 TARGETS UP 203135All SZGR 2.0 genes in this pathway
TSENG IRS1 TARGETS DN 13588All SZGR 2.0 genes in this pathway
KEEN RESPONSE TO ROSIGLITAZONE DN 10668All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS PEAK AT 0HR 6348All SZGR 2.0 genes in this pathway
TSENG ADIPOGENIC POTENTIAL DN 4628All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS 9 9259All SZGR 2.0 genes in this pathway
MARTINEZ RB1 TARGETS DN 543317All SZGR 2.0 genes in this pathway
MARTINEZ TP53 TARGETS DN 593372All SZGR 2.0 genes in this pathway
MARTINEZ RB1 AND TP53 TARGETS DN 591366All SZGR 2.0 genes in this pathway
IZADPANAH STEM CELL ADIPOSE VS BONE DN 10868All SZGR 2.0 genes in this pathway
MISHRA CARCINOMA ASSOCIATED FIBROBLAST DN 2413All SZGR 2.0 genes in this pathway
VART KSHV INFECTION ANGIOGENIC MARKERS UP 165118All SZGR 2.0 genes in this pathway
MCMURRAY TP53 HRAS COOPERATION RESPONSE DN 6746All SZGR 2.0 genes in this pathway
MEISSNER BRAIN HCP WITH H3K4ME3 AND H3K27ME3 1069729All SZGR 2.0 genes in this pathway
KARLSSON TGFB1 TARGETS DN 207139All SZGR 2.0 genes in this pathway
PURBEY TARGETS OF CTBP1 NOT SATB1 UP 344215All SZGR 2.0 genes in this pathway
KATSANOU ELAVL1 TARGETS DN 14888All SZGR 2.0 genes in this pathway
WANG MLL TARGETS 289188All SZGR 2.0 genes in this pathway
DURAND STROMA S UP 297194All SZGR 2.0 genes in this pathway
NABA SECRETED FACTORS 344197All SZGR 2.0 genes in this pathway
NABA MATRISOME ASSOCIATED 753411All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028559All SZGR 2.0 genes in this pathway