Gene Page: CSMD1

Summary ?
GeneID64478
SymbolCSMD1
SynonymsPPP1R24
DescriptionCUB and Sushi multiple domains 1
ReferenceMIM:608397|HGNC:HGNC:14026|Ensembl:ENSG00000183117|HPRD:10523|Vega:OTTHUMG00000163605
Gene typeprotein-coding
Map location8p23.2
Sherlock p-value0.929
Fetal beta-0.184
eGeneMyers' cis & trans
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWAScatGenome-wide Association StudiesThis data set includes 560 SNPs associated with schizophrenia. A total of 486 genes were mapped to these SNPs within 50kb.
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGC128Genome-wide Association StudyA multi-stage schizophrenia GWAS of up to 36,989 cases and 113,075 controls. Reported by the Schizophrenia Working Group of PGC. 128 independent associations spanning 108 loci
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@CV:PGC128

SNP IDChromosomePositionAllelePFunctionGeneUp/Down Distance
rs10503253chr84180844AC2.694E-8intronicCSMD1

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs17029291chr332402138CSMD1644780trans
rs7078127chr1074847633CSMD1644780.08trans
rs12569493chr1074886042CSMD1644780.06trans
rs16930362chr1074890320CSMD1644780trans
rs7092445chr1074921991CSMD1644780.02trans
rs12256576chr1074934313CSMD1644780.1trans
rs1867565chr1074977780CSMD1644780.02trans
rs11000557chr1074987393CSMD1644780.03trans
rs12569470chr1074995826CSMD1644780.1trans
rs16915029chr1075001994CSMD1644780.03trans
rs14488chr1075007274CSMD1644780.06trans
rs16930466chr1075007587CSMD1644780.04trans
rs11000579chr1075027961CSMD1644780.01trans
rs11000594chr1075064566CSMD1644780.14trans
rs11000607chr1075089777CSMD1644780trans
rs6480700chr1075101689CSMD1644780.07trans
rs16930573chr1075167645CSMD1644780.14trans
rs12571454chr1075208954CSMD1644780.03trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
HATADA METHYLATED IN LUNG CANCER UP 390236All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS 1038678All SZGR 2.0 genes in this pathway
BENPORATH EED TARGETS 1062725All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3 1118744All SZGR 2.0 genes in this pathway
BENPORATH PRC2 TARGETS 652441All SZGR 2.0 genes in this pathway
MEISSNER NPC HCP WITH H3K4ME3 AND H3K27ME3 142103All SZGR 2.0 genes in this pathway
MIKKELSEN NPC HCP WITH H3K4ME3 AND H3K27ME3 210148All SZGR 2.0 genes in this pathway
MIKKELSEN MEF HCP WITH H3K27ME3 590403All SZGR 2.0 genes in this pathway
PEDRIOLI MIR31 TARGETS UP 221120All SZGR 2.0 genes in this pathway