Gene Page: GIGYF1
Summary ?
| GeneID | 64599 |
| Symbol | GIGYF1 |
| Synonyms | GYF1|PERQ1 |
| Description | GRB10 interacting GYF protein 1 |
| Reference | MIM:612064|HGNC:HGNC:9126|Ensembl:ENSG00000146830|HPRD:10145|Vega:OTTHUMG00000157036 |
| Gene type | protein-coding |
| Map location | 7q22 |
| Pascal p-value | 1.965E-4 |
| Sherlock p-value | 0.869 |
| eGene | Putamen basal ganglia Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs6576747 | chr1 | 85530213 | GIGYF1 | 64599 | 0.18 | trans | ||
| rs16829545 | chr2 | 151977407 | GIGYF1 | 64599 | 4.086E-5 | trans | ||
| rs7630486 | chr3 | 189801990 | GIGYF1 | 64599 | 0.17 | trans | ||
| rs16955618 | chr15 | 29937543 | GIGYF1 | 64599 | 2.878E-4 | trans | ||
| rs1761450 | chr19 | 54818034 | GIGYF1 | 64599 | 0.12 | trans | ||
| rs16996420 | chr20 | 9780867 | GIGYF1 | 64599 | 0.13 | trans | ||
| rs221789 | 7 | 100271521 | GIGYF1 | ENSG00000146830.9 | 9.962E-7 | 0 | 15550 | gtex_brain_putamen_basal |
| rs221792 | 7 | 100278657 | GIGYF1 | ENSG00000146830.9 | 2.406E-7 | 0 | 8414 | gtex_brain_putamen_basal |
| rs221794 | 7 | 100281768 | GIGYF1 | ENSG00000146830.9 | 2.238E-7 | 0 | 5303 | gtex_brain_putamen_basal |
| rs221798 | 7 | 100287495 | GIGYF1 | ENSG00000146830.9 | 4.012E-7 | 0 | -424 | gtex_brain_putamen_basal |
| rs221784 | 7 | 100292830 | GIGYF1 | ENSG00000146830.9 | 2.184E-7 | 0 | -5759 | gtex_brain_putamen_basal |
| rs221781 | 7 | 100295908 | GIGYF1 | ENSG00000146830.9 | 1.123E-6 | 0 | -8837 | gtex_brain_putamen_basal |
| rs221780 | 7 | 100297035 | GIGYF1 | ENSG00000146830.9 | 2.184E-7 | 0 | -9964 | gtex_brain_putamen_basal |
| rs221778 | 7 | 100298024 | GIGYF1 | ENSG00000146830.9 | 2.302E-7 | 0 | -10953 | gtex_brain_putamen_basal |
| rs221774 | 7 | 100298984 | GIGYF1 | ENSG00000146830.9 | 4.012E-7 | 0 | -11913 | gtex_brain_putamen_basal |
| rs2432929 | 7 | 100299028 | GIGYF1 | ENSG00000146830.9 | 1.076E-7 | 0 | -11957 | gtex_brain_putamen_basal |
| rs221770 | 7 | 100302094 | GIGYF1 | ENSG00000146830.9 | 1.076E-7 | 0 | -15023 | gtex_brain_putamen_basal |
| rs534043 | 7 | 100312724 | GIGYF1 | ENSG00000146830.9 | 2.533E-6 | 0 | -25653 | gtex_brain_putamen_basal |
| rs492430 | 7 | 100313099 | GIGYF1 | ENSG00000146830.9 | 2.691E-6 | 0 | -26028 | gtex_brain_putamen_basal |
| rs506597 | 7 | 100313420 | GIGYF1 | ENSG00000146830.9 | 4.012E-7 | 0 | -26349 | gtex_brain_putamen_basal |
| rs1734907 | 7 | 100315517 | GIGYF1 | ENSG00000146830.9 | 2.691E-6 | 0 | -28446 | gtex_brain_putamen_basal |
| rs564449 | 7 | 100321138 | GIGYF1 | ENSG00000146830.9 | 1.8E-6 | 0 | -34067 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| GINESTIER BREAST CANCER ZNF217 AMPLIFIED DN | 335 | 193 | All SZGR 2.0 genes in this pathway |
| GRADE COLON CANCER UP | 871 | 505 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN IPS HCP WITH H3 UNMETHYLATED | 80 | 50 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN ES HCP WITH H3 UNMETHYLATED | 63 | 31 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN MEF HCP WITH H3 UNMETHYLATED | 228 | 119 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |
| ZWANG EGF INTERVAL DN | 214 | 124 | All SZGR 2.0 genes in this pathway |