Summary ?
GeneID6553
SymbolSLC9A5
SynonymsNHE5
Descriptionsolute carrier family 9 member A5
ReferenceMIM:600477|HGNC:HGNC:11078|Ensembl:ENSG00000135740|HPRD:02723|Vega:OTTHUMG00000172935
Gene typeprotein-coding
Map location16q22.1
Pascal p-value0.021
Sherlock p-value0.722
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs17572651chr1218943612SLC9A565530.17trans
rs16829545chr2151977407SLC9A565531.148E-6trans
rs3845734chr2171125572SLC9A565530.11trans
rs7584986chr2184111432SLC9A565530trans
rs17762315chr576807576SLC9A565539.123E-4trans
rs7729096chr576835927SLC9A565530.15trans
rs1368303chr5147672388SLC9A565530.12trans
rs7020639chr971907868SLC9A565530trans
rs16955618chr1529937543SLC9A565531.155E-11trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
NUP930.770.84
DISP10.750.78
CXXC40.750.76
HCN30.750.84
PCDHB180.740.83
ZCCHC80.740.83
C1orf1870.740.84
EDARADD0.740.77
VAV20.730.84
PALMD0.730.67
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
HLA-F-0.58-0.73
AIFM3-0.57-0.70
TSC22D4-0.56-0.72
FBXO2-0.56-0.64
S100B-0.55-0.76
ALDOC-0.55-0.64
C5orf53-0.55-0.70
CLU-0.55-0.65
HEPN1-0.55-0.68
AF347015.27-0.54-0.78

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES 413270All SZGR 2.0 genes in this pathway
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 241157All SZGR 2.0 genes in this pathway
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 9465All SZGR 2.0 genes in this pathway
GAL LEUKEMIC STEM CELL UP 13378All SZGR 2.0 genes in this pathway
GOZGIT ESR1 TARGETS DN 781465All SZGR 2.0 genes in this pathway
GEORGES TARGETS OF MIR192 AND MIR215 893528All SZGR 2.0 genes in this pathway
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1 419273All SZGR 2.0 genes in this pathway
MARSON BOUND BY E2F4 UNSTIMULATED 728415All SZGR 2.0 genes in this pathway
WONG MITOCHONDRIA GENE MODULE 217122All SZGR 2.0 genes in this pathway
GRADE COLON CANCER UP 871505All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA HAPTOTAXIS DN 668419All SZGR 2.0 genes in this pathway
GOBERT OLIGODENDROCYTE DIFFERENTIATION UP 570339All SZGR 2.0 genes in this pathway