Gene Page: SLCO2A1

Summary ?
GeneID6578
SymbolSLCO2A1
SynonymsMATR1|OATP2A1|PGT|PHOAR2|SLC21A2
Descriptionsolute carrier organic anion transporter family member 2A1
ReferenceMIM:601460|HGNC:HGNC:10955|Ensembl:ENSG00000174640|HPRD:03269|Vega:OTTHUMG00000159745
Gene typeprotein-coding
Map location3q21
Pascal p-value0.004
Sherlock p-value0.792
eGeneCortex
Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs1440176chr1112643779SLCO2A165780.03trans
rs13395192chr212776302SLCO2A165780.07trans
rs6756986chr297881266SLCO2A165780.01trans
rs4630919chr32082448SLCO2A165780.13trans
rs2625966chr3129267056SLCO2A165780.01trans
rs2640017chr3141335120SLCO2A165780.04trans
rs9917710chr3176280218SLCO2A165780.08trans
rs12516216chr561092624SLCO2A165780.01trans
rs17081113chr6151637449SLCO2A165780.19trans
rs17124783chr817395794SLCO2A165780.12trans
rs16904143chr8130702810SLCO2A165780.08trans
rs11186481chr1082419692SLCO2A165780.19trans
rs11607762chr1169051044SLCO2A165780.1trans
rs4514621chr1552583152SLCO2A165780.01trans
rs16961083chr1613170784SLCO2A165780.16trans
rs281608chr1634326380SLCO2A165780.15trans
snp_a-42238540SLCO2A165780.01trans
rs4891482chr1870366897SLCO2A165780.01trans
rs17086279chr1870410202SLCO2A165780.03trans
rs11796450chrX3983128SLCO2A165782.558E-6trans
rs16978802chrX3998040SLCO2A165782.558E-6trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
MON1A0.870.87
IMP30.870.86
RNF1260.860.88
GPS10.850.84
C11orf680.850.85
GNB1L0.850.87
TMEM1800.850.84
IRF2BP10.840.86
MRPS20.840.83
C1orf700.840.87
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AF347015.8-0.68-0.68
MT-CO2-0.66-0.66
AF347015.27-0.66-0.69
AF347015.31-0.66-0.65
AF347015.33-0.66-0.67
MT-CYB-0.66-0.67
AF347015.15-0.64-0.66
AF347015.26-0.64-0.66
AF347015.21-0.64-0.66
AF347015.2-0.64-0.65

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES 413270All SZGR 2.0 genes in this pathway
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 241157All SZGR 2.0 genes in this pathway
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 3116All SZGR 2.0 genes in this pathway
REACTOME TRANSPORT OF ORGANIC ANIONS 116All SZGR 2.0 genes in this pathway
ROY WOUND BLOOD VESSEL UP 5030All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 4 5WK UP 271175All SZGR 2.0 genes in this pathway
ZIRN TRETINOIN RESPONSE UP 2113All SZGR 2.0 genes in this pathway
SAENZ DETOX PATHWAY AND CARCINOGENESIS DN 1311All SZGR 2.0 genes in this pathway
MOHANKUMAR TLX1 TARGETS DN 193112All SZGR 2.0 genes in this pathway
FURUKAWA DUSP6 TARGETS PCI35 DN 7440All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR UP 487286All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS 1038678All SZGR 2.0 genes in this pathway
BENPORATH EED TARGETS 1062725All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3 1118744All SZGR 2.0 genes in this pathway
BENPORATH PRC2 TARGETS 652441All SZGR 2.0 genes in this pathway
ROZANOV MMP14 CORRELATED 119All SZGR 2.0 genes in this pathway
ROZANOV MMP14 TARGETS UP 266171All SZGR 2.0 genes in this pathway
POMEROY MEDULLOBLASTOMA PROGNOSIS UP 4730All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 DN 830547All SZGR 2.0 genes in this pathway
BAELDE DIABETIC NEPHROPATHY UP 8648All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 48HR DN 504323All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 3 720440All SZGR 2.0 genes in this pathway
RIGGINS TAMOXIFEN RESISTANCE UP 6644All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE BY GAMMA RADIATION 8159All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE UP 226164All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER UP 973570All SZGR 2.0 genes in this pathway
ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP 863514All SZGR 2.0 genes in this pathway
WEST ADRENOCORTICAL TUMOR DN 546362All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK 1210725All SZGR 2.0 genes in this pathway
MEISSNER NPC HCP WITH H3 UNMETHYLATED 536296All SZGR 2.0 genes in this pathway
MEISSNER BRAIN HCP WITH H3K4ME3 AND H3K27ME3 1069729All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA CHEMOTAXIS DN 457302All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA HAPTOTAXIS DN 668419All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER SUBCLASS S3 266180All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 1HR DN 222147All SZGR 2.0 genes in this pathway
HIRSCH CELLULAR TRANSFORMATION SIGNATURE DN 10367All SZGR 2.0 genes in this pathway
DUTERTRE ESTRADIOL RESPONSE 24HR DN 505328All SZGR 2.0 genes in this pathway
FEVR CTNNB1 TARGETS UP 682433All SZGR 2.0 genes in this pathway
KATSANOU ELAVL1 TARGETS DN 14888All SZGR 2.0 genes in this pathway
SERVITJA LIVER HNF1A TARGETS DN 157105All SZGR 2.0 genes in this pathway
WANG MLL TARGETS 289188All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY 1725838All SZGR 2.0 genes in this pathway