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| GeneID |
6693
|
| Symbol |
SPN
|
| Synonyms |
CD43|GPL115|LSN
|
| Description |
sialophorin |
| See related |
HGNC:11249|MIM:182160|Ensembl:ENSG00000197471|HPRD:06770| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
16p11.2 |
|
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|
| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_IIE | genome scan meta-analysis (European-ancestry samples) | Psr: 0.01775 | | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| DNM1L | 0.94 | 0.93 | | |
| NKRF | 0.93 | 0.93 | | |
| PJA2 | 0.93 | 0.96 | | |
| SLC30A9 | 0.93 | 0.92 | | |
| UCHL5 | 0.93 | 0.92 | | |
| ACTR2 | 0.93 | 0.92 | | |
| SERINC1 | 0.92 | 0.91 | | |
| PAFAH1B1 | 0.92 | 0.93 | | |
| CLTC | 0.92 | 0.93 | | |
| UBQLN1 | 0.92 | 0.90 | | |
Top 10 negatively co-expressed genes | | FXYD1 | -0.73 | -0.66 | | |
| HIGD1B | -0.70 | -0.65 | | |
| MT-CO2 | -0.69 | -0.62 | | |
| GSDMD | -0.69 | -0.67 | | |
| AP002478.3 | -0.68 | -0.67 | | |
| AF347015.21 | -0.68 | -0.59 | | |
| AF347015.31 | -0.67 | -0.61 | | |
| ACSF2 | -0.67 | -0.65 | | |
| EIF4EBP3 | -0.66 | -0.68 | | |
| RAB34 | -0.66 | -0.72 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004888 | transmembrane receptor activity | TAS | | 1683685 |
| GO:0008367 | bacterial binding | IDA | | 10899905 |
| GO:0005515 | protein binding | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0001562 | response to protozoan | IEA | | - |
| GO:0001808 | negative regulation of type IV hypersensitivity | IEA | | - |
| GO:0007162 | negative regulation of cell adhesion | TAS | | 10753822 |
| GO:0006968 | cellular defense response | TAS | | 1683685 |
| GO:0007166 | cell surface receptor linked signal transduction | IEA | | - |
| GO:0007163 | establishment or maintenance of cell polarity | TAS | | 10753822 |
| GO:0006935 | chemotaxis | TAS | | 10753822 |
| GO:0008624 | induction of apoptosis by extracellular signals | IEA | | - |
| GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process | IDA | | 10899905 |
| GO:0042130 | negative regulation of T cell proliferation | IEA | | - |
| GO:0042102 | positive regulation of T cell proliferation | IEA | | - |
| GO:0042742 | defense response to bacterium | IDA | | 10899905 |
| GO:0031295 | T cell costimulation | IEA | | - |
| GO:0050688 | regulation of defense response to virus | IEA | | - |
| GO:0050776 | regulation of immune response | IEA | | - |
| GO:0045060 | negative thymic T cell selection | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0001931 | uropod | IEA | Synap (GO term level: 5) | - |
| GO:0005604 | basement membrane | IEA | | - |
| GO:0005615 | extracellular space | IDA | | 10899905 |
| GO:0016020 | membrane | IEA | | - |
| GO:0009897 | external side of plasma membrane | IEA | | - |
| GO:0005887 | integral to plasma membrane | TAS | | 2023632 |
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