Gene Page: TAF4

Summary ?
GeneID6874
SymbolTAF4
SynonymsTAF2C|TAF2C1|TAF4A|TAFII130|TAFII135
DescriptionTATA-box binding protein associated factor 4
ReferenceMIM:601796|HGNC:HGNC:11537|Ensembl:ENSG00000130699|HPRD:11797|Vega:OTTHUMG00000032893
Gene typeprotein-coding
Map location20q13.33
Pascal p-value0.214
Sherlock p-value0.023
Fetal beta1.114
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs2068673chr1260333402TAF468740.02trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section IV. Protein-protein interaction annotation

InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AHR-aryl hydrocarbon receptorAHR interacts with TAF4.BIND15641800 
ATF7ATFA | MGC57182activating transcription factor 7TAF4 interacts ATF7.BIND15735663 
CBX5HP1 | HP1Achromobox homolog 5 (HP1 alpha homolog, Drosophila)-HPRD,BioGRID11959914 
CREMICER | MGC111110 | MGC17881 | MGC41893 | hCREM-2cAMP responsive element modulator-HPRD,BioGRID10409662 
GTF2A1MGC129969 | MGC129970 | TF2A1 | TFIIAgeneral transcription factor IIA, 1, 19/37kDa-HPRD11564872 
GTF2A2HsT18745 | TF2A2 | TFIIAgeneral transcription factor IIA, 2, 12kDa-HPRD,BioGRID11564872 
HTTHD | IT15huntingtinTAFII130 interacts with htt.BIND11988536 
HTTHD | IT15huntingtin-HPRD11988536 
KAT2AGCN5 | GCN5L2 | MGC102791 | PCAF-b | hGCN5K(lysine) acetyltransferase 2AAffinity Capture-WesternBioGRID11406595 
SAP130FLJ12761Sin3A-associated protein, 130kDaAffinity Capture-WesternBioGRID11406595 
SP1-Sp1 transcription factor-HPRD,BioGRID9742090 
SUPT3HSPT3 | SPT3Lsuppressor of Ty 3 homolog (S. cerevisiae)Affinity Capture-WesternBioGRID11406595 
TAF1BA2R | CCG1 | CCGS | DYT3 | KAT4 | N-TAF1 | NSCL2 | OF | P250 | TAF2A | TAFII250TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa-HPRD,BioGRID11564872 
TAF10TAF2A | TAF2H | TAFII30TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDaAffinity Capture-WesternBioGRID11406595 
TAF12TAF2J | TAFII20TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDaFar WesternBioGRID11564872 
TAF4FLJ41943 | TAF2C | TAF2C1 | TAF4A | TAFII130 | TAFII135TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDaFar WesternBioGRID11564872 
TAF5TAF2D | TAFII100TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDaAffinity Capture-WesternBioGRID11406595 
TAF843 | FLJ32821 | II | TAF | TAFII43 | TBNTAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDaFar WesternBioGRID11564872 
TBPGTF2D | GTF2D1 | MGC117320 | MGC126054 | MGC126055 | SCA17 | TFIIDTATA box binding proteinAffinity Capture-Western
Co-purification		BioGRID9153318 |12665565 


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG BASAL TRANSCRIPTION FACTORS 3624All SZGR 2.0 genes in this pathway
KEGG HUNTINGTONS DISEASE 185109All SZGR 2.0 genes in this pathway
REACTOME RNA POL II TRANSCRIPTION 10554All SZGR 2.0 genes in this pathway
REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING 4121All SZGR 2.0 genes in this pathway
REACTOME TRANSCRIPTION 210127All SZGR 2.0 genes in this pathway
REACTOME RNA POL II PRE TRANSCRIPTION EVENTS 6132All SZGR 2.0 genes in this pathway
REACTOME HIV INFECTION 207122All SZGR 2.0 genes in this pathway
REACTOME HIV LIFE CYCLE 12569All SZGR 2.0 genes in this pathway
REACTOME LATE PHASE OF HIV LIFE CYCLE 10461All SZGR 2.0 genes in this pathway
NAGY TFTC COMPONENTS HUMAN 1911All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 DN 855609All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 COMMON DN 483336All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC NETWORK 16521023All SZGR 2.0 genes in this pathway
PUJANA BRCA2 PCC NETWORK 423265All SZGR 2.0 genes in this pathway
PUJANA CHEK2 PCC NETWORK 779480All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 20Q12 Q13 AMPLICON 14976All SZGR 2.0 genes in this pathway
THEILGAARD NEUTROPHIL AT SKIN WOUND DN 225163All SZGR 2.0 genes in this pathway
KAYO AGING MUSCLE DN 12376All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 10HR UP 10169All SZGR 2.0 genes in this pathway
KRASNOSELSKAYA ILF3 TARGETS DN 4638All SZGR 2.0 genes in this pathway
BILD E2F3 ONCOGENIC SIGNATURE 246153All SZGR 2.0 genes in this pathway
AGUIRRE PANCREATIC CANCER COPY NUMBER UP 298174All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 19721213All SZGR 2.0 genes in this pathway
PURBEY TARGETS OF CTBP1 NOT SATB1 UP 344215All SZGR 2.0 genes in this pathway
GOBERT OLIGODENDROCYTE DIFFERENTIATION UP 570339All SZGR 2.0 genes in this pathway