Gene Page: TAF10
Summary ?
| GeneID | 6881 |
| Symbol | TAF10 |
| Synonyms | TAF2A|TAF2H|TAFII30 |
| Description | TATA-box binding protein associated factor 10 |
| Reference | MIM:600475|HGNC:HGNC:11543|HPRD:15972| |
| Gene type | protein-coding |
| Map location | 11p15.3 |
| Pascal p-value | 0.011 |
| Sherlock p-value | 0.608 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| PARK7 | 0.86 | 0.87 |
| UQCRH | 0.83 | 0.85 |
| SKP1 | 0.82 | 0.81 |
| SSBP1 | 0.81 | 0.82 |
| ATP5F1 | 0.81 | 0.84 |
| MYL12B | 0.81 | 0.83 |
| VPS29 | 0.81 | 0.80 |
| ATP5C1 | 0.80 | 0.83 |
| PSMA6 | 0.80 | 0.84 |
| GTF3A | 0.80 | 0.79 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.26 | -0.54 | -0.43 |
| AF347015.18 | -0.54 | -0.39 |
| PPP1R13L | -0.52 | -0.46 |
| TENC1 | -0.51 | -0.52 |
| FAM38A | -0.51 | -0.51 |
| AF347015.2 | -0.50 | -0.39 |
| DOCK6 | -0.50 | -0.48 |
| GATA2 | -0.49 | -0.48 |
| TBX2 | -0.49 | -0.46 |
| CASKIN2 | -0.48 | -0.46 |
Section IV. Protein-protein interaction annotation
| Interactors | Aliases B | Official full name B | Experimental | Source | PubMed ID |
|---|---|---|---|---|---|
| CECR2 | KIAA1740 | cat eye syndrome chromosome region, candidate 2 | Two-hybrid | BioGRID | 12762840 |
| ESR1 | DKFZp686N23123 | ER | ESR | ESRA | Era | NR3A1 | estrogen receptor 1 | - | HPRD | 7923369 |
| FANCA | FA | FA-H | FA1 | FAA | FACA | FAH | FANCH | MGC75158 | Fanconi anemia, complementation group A | Two-hybrid | BioGRID | 14499622 |
| FTL | MGC71996 | ferritin, light polypeptide | Two-hybrid | BioGRID | 16169070 |
| MYC | bHLHe39 | c-Myc | v-myc myelocytomatosis viral oncogene homolog (avian) | Co-purification | BioGRID | 12660246 |
| POLR2A | MGC75453 | POLR2 | POLRA | RPB1 | RPBh1 | RPO2 | RPOL2 | RpIILS | hRPB220 | hsRPB1 | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | - | HPRD | 15099517 |
| SUPT3H | SPT3 | SPT3L | suppressor of Ty 3 homolog (S. cerevisiae) | Affinity Capture-Western | BioGRID | 11406595 |
| TAF1 | BA2R | CCG1 | CCGS | DYT3 | KAT4 | N-TAF1 | NSCL2 | OF | P250 | TAF2A | TAFII250 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | - | HPRD | 7923369 |
| TAF12 | TAF2J | TAFII20 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa | - | HPRD | 7729427 |
| TAF13 | MGC22425 | TAF2K | TAFII18 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa | - | HPRD,BioGRID | 7729427 |
| TAF4 | FLJ41943 | TAF2C | TAF2C1 | TAF4A | TAFII130 | TAFII135 | TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa | Affinity Capture-Western | BioGRID | 11406595 |
| TAF8 | 43 | FLJ32821 | II | TAF | TAFII43 | TBN | TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa | - | HPRD | 14580349 |
| TBP | GTF2D | GTF2D1 | MGC117320 | MGC126054 | MGC126055 | SCA17 | TFIID | TATA box binding protein | - | HPRD | 7923369 |
| TBP | GTF2D | GTF2D1 | MGC117320 | MGC126054 | MGC126055 | SCA17 | TFIID | TATA box binding protein | Co-purification | BioGRID | 7680771 |9153318 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG BASAL TRANSCRIPTION FACTORS | 36 | 24 | All SZGR 2.0 genes in this pathway |
| PID MYC ACTIV PATHWAY | 79 | 62 | All SZGR 2.0 genes in this pathway |
| PID MYC PATHWAY | 25 | 22 | All SZGR 2.0 genes in this pathway |
| REACTOME RNA POL II TRANSCRIPTION | 105 | 54 | All SZGR 2.0 genes in this pathway |
| REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | 41 | 21 | All SZGR 2.0 genes in this pathway |
| REACTOME TRANSCRIPTION | 210 | 127 | All SZGR 2.0 genes in this pathway |
| REACTOME RNA POL II PRE TRANSCRIPTION EVENTS | 61 | 32 | All SZGR 2.0 genes in this pathway |
| REACTOME HIV INFECTION | 207 | 122 | All SZGR 2.0 genes in this pathway |
| REACTOME HIV LIFE CYCLE | 125 | 69 | All SZGR 2.0 genes in this pathway |
| REACTOME LATE PHASE OF HIV LIFE CYCLE | 104 | 61 | All SZGR 2.0 genes in this pathway |
| LIU SOX4 TARGETS DN | 309 | 191 | All SZGR 2.0 genes in this pathway |
| GARY CD5 TARGETS UP | 473 | 314 | All SZGR 2.0 genes in this pathway |
| HORIUCHI WTAP TARGETS DN | 310 | 188 | All SZGR 2.0 genes in this pathway |
| NAGY TFTC COMPONENTS HUMAN | 19 | 11 | All SZGR 2.0 genes in this pathway |
| NAGY STAGA COMPONENTS HUMAN | 15 | 8 | All SZGR 2.0 genes in this pathway |
| NAGY PCAF COMPONENTS HUMAN | 9 | 7 | All SZGR 2.0 genes in this pathway |
| DIRMEIER LMP1 RESPONSE LATE DN | 32 | 22 | All SZGR 2.0 genes in this pathway |
| SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN UP | 479 | 299 | All SZGR 2.0 genes in this pathway |
| PENG RAPAMYCIN RESPONSE UP | 203 | 130 | All SZGR 2.0 genes in this pathway |
| TAKAO RESPONSE TO UVB RADIATION UP | 86 | 55 | All SZGR 2.0 genes in this pathway |
| SESTO RESPONSE TO UV C7 | 68 | 44 | All SZGR 2.0 genes in this pathway |
| JIANG AGING HYPOTHALAMUS UP | 47 | 31 | All SZGR 2.0 genes in this pathway |
| DOUGLAS BMI1 TARGETS DN | 314 | 188 | All SZGR 2.0 genes in this pathway |
| KYNG ENVIRONMENTAL STRESS RESPONSE NOT BY 4NQO IN OLD | 13 | 10 | All SZGR 2.0 genes in this pathway |
| KYNG ENVIRONMENTAL STRESS RESPONSE NOT BY 4NQO IN WS | 40 | 26 | All SZGR 2.0 genes in this pathway |
| KYNG ENVIRONMENTAL STRESS RESPONSE NOT BY GAMMA IN OLD | 31 | 19 | All SZGR 2.0 genes in this pathway |
| KYNG ENVIRONMENTAL STRESS RESPONSE NOT BY UV IN OLD | 25 | 18 | All SZGR 2.0 genes in this pathway |
| KYNG DNA DAMAGE DN | 195 | 135 | All SZGR 2.0 genes in this pathway |
| KYNG ENVIRONMENTAL STRESS RESPONSE UP | 56 | 41 | All SZGR 2.0 genes in this pathway |
| RIZKI TUMOR INVASIVENESS 2D UP | 69 | 46 | All SZGR 2.0 genes in this pathway |
| MALONEY RESPONSE TO 17AAG UP | 41 | 26 | All SZGR 2.0 genes in this pathway |
| TOOKER GEMCITABINE RESISTANCE UP | 79 | 40 | All SZGR 2.0 genes in this pathway |
| CHAUHAN RESPONSE TO METHOXYESTRADIOL DN | 102 | 65 | All SZGR 2.0 genes in this pathway |
| KYNG NORMAL AGING UP | 19 | 11 | All SZGR 2.0 genes in this pathway |
| KYNG WERNER SYNDROM DN | 29 | 14 | All SZGR 2.0 genes in this pathway |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 17 | 181 | 101 | All SZGR 2.0 genes in this pathway |
| KYNG RESPONSE TO H2O2 VIA ERCC6 UP | 40 | 30 | All SZGR 2.0 genes in this pathway |
| KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR UP | 756 | 494 | All SZGR 2.0 genes in this pathway |
| KIM BIPOLAR DISORDER OLIGODENDROCYTE DENSITY CORR UP | 682 | 440 | All SZGR 2.0 genes in this pathway |
| PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 2 UP | 140 | 94 | All SZGR 2.0 genes in this pathway |
| LIM MAMMARY STEM CELL DN | 428 | 246 | All SZGR 2.0 genes in this pathway |
| ZWANG EGF INTERVAL DN | 214 | 124 | All SZGR 2.0 genes in this pathway |