Summary ?
GeneID6883
SymbolTAF12
SynonymsTAF2J|TAFII20
DescriptionTATA-box binding protein associated factor 12
ReferenceMIM:600773|HGNC:HGNC:11545|Ensembl:ENSG00000120656|HPRD:15981|Vega:OTTHUMG00000003655
Gene typeprotein-coding
Map location1p35.3
Pascal p-value0.002
Sherlock p-value0.071

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
NDUFA110.930.90
PHPT10.920.90
SSR40.910.90
AP000350.60.910.88
TRAPPC50.900.82
ROMO10.900.83
AC009171.10.890.87
ANAPC110.880.91
CHCHD50.880.83
KRTCAP20.880.82
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
Z83840.4-0.50-0.65
MYH9-0.48-0.49
COBLL1-0.47-0.55
CCDC55-0.47-0.51
ZNHIT6-0.47-0.47
FLT1-0.47-0.58
DST-0.46-0.51
TRIM44-0.45-0.53
SWAP70-0.45-0.48
UTRN-0.45-0.50

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG BASAL TRANSCRIPTION FACTORS 3624All SZGR 2.0 genes in this pathway
PID MYC ACTIV PATHWAY 7962All SZGR 2.0 genes in this pathway
PID MYC PATHWAY 2522All SZGR 2.0 genes in this pathway
REACTOME RNA POL II TRANSCRIPTION 10554All SZGR 2.0 genes in this pathway
REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING 4121All SZGR 2.0 genes in this pathway
REACTOME TRANSCRIPTION 210127All SZGR 2.0 genes in this pathway
REACTOME RNA POL II PRE TRANSCRIPTION EVENTS 6132All SZGR 2.0 genes in this pathway
REACTOME HIV INFECTION 207122All SZGR 2.0 genes in this pathway
REACTOME HIV LIFE CYCLE 12569All SZGR 2.0 genes in this pathway
REACTOME LATE PHASE OF HIV LIFE CYCLE 10461All SZGR 2.0 genes in this pathway
GAZDA DIAMOND BLACKFAN ANEMIA ERYTHROID DN 493298All SZGR 2.0 genes in this pathway
BORCZUK MALIGNANT MESOTHELIOMA UP 305185All SZGR 2.0 genes in this pathway
LASTOWSKA NEUROBLASTOMA COPY NUMBER DN 800473All SZGR 2.0 genes in this pathway
NAGY TFTC COMPONENTS HUMAN 1911All SZGR 2.0 genes in this pathway
NAGY STAGA COMPONENTS HUMAN 158All SZGR 2.0 genes in this pathway
NAGY PCAF COMPONENTS HUMAN 97All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC NETWORK 16521023All SZGR 2.0 genes in this pathway
BENPORATH NANOG TARGETS 988594All SZGR 2.0 genes in this pathway
BENPORATH OCT4 TARGETS 290172All SZGR 2.0 genes in this pathway
BENPORATH SOX2 TARGETS 734436All SZGR 2.0 genes in this pathway
BENPORATH NOS TARGETS 179105All SZGR 2.0 genes in this pathway
GOTTWEIN TARGETS OF KSHV MIR K12 11 6345All SZGR 2.0 genes in this pathway
ROZANOV MMP14 TARGETS UP 266171All SZGR 2.0 genes in this pathway
WELCSH BRCA1 TARGETS UP 198132All SZGR 2.0 genes in this pathway
RIZKI TUMOR INVASIVENESS 2D UP 6946All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER UP 973570All SZGR 2.0 genes in this pathway
ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP 863514All SZGR 2.0 genes in this pathway
AGUIRRE PANCREATIC CANCER COPY NUMBER DN 238145All SZGR 2.0 genes in this pathway
KESHELAVA MULTIPLE DRUG RESISTANCE 8856All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA CLASSES UP 605377All SZGR 2.0 genes in this pathway
WANG RESPONSE TO GSK3 INHIBITOR SB216763 UP 397206All SZGR 2.0 genes in this pathway