Summary ?
GeneID6975
SymbolTECTB
Synonyms-
Descriptiontectorin beta
ReferenceMIM:602653|HGNC:HGNC:11721|Ensembl:ENSG00000119913|HPRD:16005|Vega:OTTHUMG00000019056
Gene typeprotein-coding
Map location10q25-q26
Pascal p-value0.027
Fetal beta-0.617
DMG1 (# studies)
eGeneCaudate basal ganglia
Cortex
Putamen basal ganglia

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Wockner_2014Genome-wide DNA methylation analysisThis dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 3

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg0035722110114043412TECTB6.5E-5-0.4310.024DMG:Wockner_2014
cg1034331410114043305TECTB3.605E-4-0.3910.042DMG:Wockner_2014
cg0992546710114043123TECTB5.739E-4-0.6010.049DMG:Wockner_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs7658643510113994235TECTBENSG00000119913.44.258E-60.03-49258gtex_brain_putamen_basal
rs1235812610113995337TECTBENSG00000119913.44.258E-60.03-48156gtex_brain_putamen_basal
rs11572979310114000610TECTBENSG00000119913.41.675E-60.03-42883gtex_brain_putamen_basal
rs11603482810114000634TECTBENSG00000119913.41.675E-60.03-42859gtex_brain_putamen_basal
rs7944636710114002449TECTBENSG00000119913.44.258E-60.03-41044gtex_brain_putamen_basal
rs1119585210114009165TECTBENSG00000119913.44.258E-60.03-34328gtex_brain_putamen_basal
rs1235656810114010837TECTBENSG00000119913.44.258E-60.03-32656gtex_brain_putamen_basal
rs20072410210114011226TECTBENSG00000119913.44.258E-60.03-32267gtex_brain_putamen_basal
rs707251410114011803TECTBENSG00000119913.44.143E-60.03-31690gtex_brain_putamen_basal
rs1235514410114012876TECTBENSG00000119913.44.258E-60.03-30617gtex_brain_putamen_basal
rs20029648410114016039TECTBENSG00000119913.41.705E-60.03-27454gtex_brain_putamen_basal
rs7761579110114017356TECTBENSG00000119913.44.258E-60.03-26137gtex_brain_putamen_basal
rs11776539110114018097TECTBENSG00000119913.42.018E-60.03-25396gtex_brain_putamen_basal
rs1181542510114022661TECTBENSG00000119913.44.258E-60.03-20832gtex_brain_putamen_basal
rs1767226810114023390TECTBENSG00000119913.44.258E-60.03-20103gtex_brain_putamen_basal
rs1235843410114025839TECTBENSG00000119913.44.258E-60.03-17654gtex_brain_putamen_basal
rs1181765410114026723TECTBENSG00000119913.44.258E-60.03-16770gtex_brain_putamen_basal
rs1235886310114026909TECTBENSG00000119913.44.258E-60.03-16584gtex_brain_putamen_basal
rs789552710114030652TECTBENSG00000119913.44.258E-60.03-12841gtex_brain_putamen_basal
rs1119586110114032654TECTBENSG00000119913.44.258E-60.03-10839gtex_brain_putamen_basal
rs1119586410114035837TECTBENSG00000119913.44.258E-60.03-7656gtex_brain_putamen_basal
rs1119586910114041244TECTBENSG00000119913.44.013E-60.03-2249gtex_brain_putamen_basal
rs1119587010114043240TECTBENSG00000119913.43.94E-60.03-253gtex_brain_putamen_basal
rs790507810114047059TECTBENSG00000119913.42.431E-60.033566gtex_brain_putamen_basal
rs19981250010114048104TECTBENSG00000119913.44.142E-60.034611gtex_brain_putamen_basal
rs1119587510114048105TECTBENSG00000119913.44.133E-60.034612gtex_brain_putamen_basal
rs7484803910114049630TECTBENSG00000119913.44.007E-60.036137gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
MCCLUNG COCAIN REWARD 4WK 7547All SZGR 2.0 genes in this pathway
NABA ECM GLYCOPROTEINS 19699All SZGR 2.0 genes in this pathway
NABA CORE MATRISOME 275148All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028559All SZGR 2.0 genes in this pathway